CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 27 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
13
With full pages
3
Scaffold SMILES

O=C(CCN1C(=O)C(=Cc2ccccc2)SC1=S)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCN1C(=O)C(=Cc2ccccc2)SC1=S)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

3-[(5Z)-5-(3,4-Dimethoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-(2-phenylethyl)propanamide chemical structure, C23H24N2O4S2, CAS 425661-52-5
3-[(5Z)-5-(3,4-Dimethoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-(2-phenylethyl)propanamide
CAS 425661-52-5C23H24N2O4S2
N-[2-(4-Hydroxyphenyl)ethyl]-3-[(5Z)-5-(2-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanamide chemical structure, C22H22N2O4S2, CAS 902041-51-4
N-[2-(4-Hydroxyphenyl)ethyl]-3-[(5Z)-5-(2-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanamide
CAS 902041-51-4C22H22N2O4S2
3-[(5Z)-5-(4-Chlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-[2-(4-hydroxyphenyl)ethyl]propanamide chemical structure, C21H19ClN2O3S2, CAS 902018-84-2
3-[(5Z)-5-(4-Chlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-[2-(4-hydroxyphenyl)ethyl]propanamide
CAS 902018-84-2C21H19ClN2O3S2
3-[(5Z)-5-(3-Fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-[2-(4-hydroxyphenyl)ethyl]propanamide chemical structure, C21H19FN2O3S2, CAS 902050-68-4
3-[(5Z)-5-(3-Fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-[2-(4-hydroxyphenyl)ethyl]propanamide
CAS 902050-68-4C21H19FN2O3S2
3-[(5Z)-5-(3-Chlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-[2-(4-hydroxyphenyl)ethyl]propanamide chemical structure, C21H19ClN2O3S2, CAS 902313-94-4
3-[(5Z)-5-(3-Chlorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-[2-(4-hydroxyphenyl)ethyl]propanamide
CAS 902313-94-4C21H19ClN2O3S2
N-[2-(4-Hydroxyphenyl)ethyl]-3-[(5Z)-5-(3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanamide chemical structure, C22H22N2O4S2, CAS 902324-80-5
N-[2-(4-Hydroxyphenyl)ethyl]-3-[(5Z)-5-(3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanamide
CAS 902324-80-5C22H22N2O4S2
3-[(5Z)-5-(2-Fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-[2-(4-hydroxyphenyl)ethyl]propanamide chemical structure, C21H19FN2O3S2, CAS 902315-12-2
3-[(5Z)-5-(2-Fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-N-[2-(4-hydroxyphenyl)ethyl]propanamide
CAS 902315-12-2C21H19FN2O3S2
(E)-N-(1-Hydroxy-3-phenylpropan-2-yl)-3-(5-(4-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanamide chemical structure, C23H24N2O4S2, CAS 900134-76-1
(E)-N-(1-Hydroxy-3-phenylpropan-2-yl)-3-(5-(4-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanamide
CAS 900134-76-1C23H24N2O4S2
(Z)-3-(5-(2-Chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-N-(1-hydroxy-3-phenylpropan-2-yl)propanamide chemical structure, C22H21ClN2O3S2, CAS 900135-02-6
(Z)-3-(5-(2-Chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-N-(1-hydroxy-3-phenylpropan-2-yl)propanamide
CAS 900135-02-6C22H21ClN2O3S2
(Z)-N-(3,4-Dimethoxyphenethyl)-3-(5-(4-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanamide chemical structure, C24H26N2O5S2, CAS 900135-27-5
(Z)-N-(3,4-Dimethoxyphenethyl)-3-(5-(4-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanamide
CAS 900135-27-5C24H26N2O5S2
(Z)-N-(3,4-Dimethoxyphenethyl)-3-(5-(3-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanamide chemical structure, C24H26N2O5S2, CAS 900135-29-7
(Z)-N-(3,4-Dimethoxyphenethyl)-3-(5-(3-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanamide
CAS 900135-29-7C24H26N2O5S2
N-(1-Hydroxy-3-phenylpropan-2-yl)-3-[(5Z)-5-(2-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanamide chemical structure, C23H24N2O4S2, CAS 900135-35-5
N-(1-Hydroxy-3-phenylpropan-2-yl)-3-[(5Z)-5-(2-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanamide
CAS 900135-35-5C23H24N2O4S2
3-[(5Z)-5-[(3-Chlorophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-(1-hydroxy-3-phenylpropan-2-yl)propanamide chemical structure, C22H21ClN2O3S2, CAS 900135-47-9
3-[(5Z)-5-[(3-Chlorophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-(1-hydroxy-3-phenylpropan-2-yl)propanamide
CAS 900135-47-9C22H21ClN2O3S2