CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 28 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
28
Chemicals
10
With full pages
4
Scaffold SMILES

O=C(CCN1C(=O)C(=Cc2ccccc2)SC1=S)NNC(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCN1C(=O)C(=Cc2ccccc2)SC1=S)NNC(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

(Z)-2-Methoxy-N'-(3-(5-(4-methylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoyl)benzohydrazide chemical structure, C22H21N3O4S2, CAS 5551-71-3
(Z)-2-Methoxy-N'-(3-(5-(4-methylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoyl)benzohydrazide
CAS 5551-71-3C22H21N3O4S2
N'-{3-[(5Z)-5-benzylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoyl}-2-bromobenzohydrazide chemical structure, C20H16BrN3O3S2, CAS 373613-09-3
N'-{3-[(5Z)-5-benzylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoyl}-2-bromobenzohydrazide
CAS 373613-09-3C20H16BrN3O3S2
2-Chloro-N'-{3-[(5E)-5-[(3-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoyl}benzohydrazide chemical structure, C21H18ClN3O4S2, CAS 300827-16-1
2-Chloro-N'-{3-[(5E)-5-[(3-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoyl}benzohydrazide
CAS 300827-16-1C21H18ClN3O4S2
(Z)-N'-(3-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)propanoyl)-2-methoxybenzohydrazide chemical structure, C21H19N3O4S2, CAS 303055-93-8
(Z)-N'-(3-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)propanoyl)-2-methoxybenzohydrazide
CAS 303055-93-8C21H19N3O4S2
2-Hydroxy-N'-{3-[5-(2-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoyl}benzohydrazide chemical structure, C21H19N3O5S2, CAS 299952-79-7
2-Hydroxy-N'-{3-[5-(2-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoyl}benzohydrazide
CAS 299952-79-7C21H19N3O5S2
2-Hydroxy-benzoic acid N'-{3-[5-(4-methyl-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-propionyl}-hydrazide chemical structure, C21H19N3O4S2, CAS 299952-80-0
2-Hydroxy-benzoic acid N'-{3-[5-(4-methyl-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-propionyl}-hydrazide
CAS 299952-80-0C21H19N3O4S2
5-[(2-Chlorophenyl)methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid 2-(3-chlorobenzoyl)hydrazide chemical structure, C20H15Cl2N3O3S2, CAS 380590-98-7
5-[(2-Chlorophenyl)methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid 2-(3-chlorobenzoyl)hydrazide
CAS 380590-98-7C20H15Cl2N3O3S2
N'-{3-[(5Z)-5-[(3,4-Dimethoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoyl}benzohydrazide chemical structure, C22H21N3O5S2, CAS 303025-73-2
N'-{3-[(5Z)-5-[(3,4-Dimethoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoyl}benzohydrazide
CAS 303025-73-2C22H21N3O5S2
2-Methoxy-N'-{3-[(5Z)-5-(3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoyl}benzohydrazide chemical structure, C22H21N3O5S2, CAS 299952-81-1
2-Methoxy-N'-{3-[(5Z)-5-(3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]propanoyl}benzohydrazide
CAS 299952-81-1C22H21N3O5S2
2-Methoxy-benzoic acid N'-{3-[5-(2-methoxy-benzylidene)-4-oxo-2-thioxo-thiazolid chemical structure, C22H21N3O5S2, CAS 300827-14-9
2-Methoxy-benzoic acid N'-{3-[5-(2-methoxy-benzylidene)-4-oxo-2-thioxo-thiazolid
CAS 300827-14-9C22H21N3O5S2