Murcko scaffold
Ring system with 7 rings and 39 atoms
7 chemicals on CompoundList share this ring system.
- Rings
- 7
- Scaffold atoms
- 39
- Chemicals
- 7
- With full pages
- 1
Scaffold SMILES
O=c1[nH]cnc2c1ncn2C1CC2O[PH](=O)OCC3OC(n4cnc5cncnc54)CC3O[PH](=O)OCC2O1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]cnc2c1ncn2C1CC2O[PH](=O)OCC3OC(n4cnc5cncnc54)CC3O[PH](=O)OCC2O1](/scaffold/DPZSDPKQFMLLSB-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 7 of 7 chemicals
c-GMP-AMP
CAS 849214-04-6C20H24N10O13P2
cAIMP
CAS 1507367-51-2C20H23N9O13P2
cGAMP (disodium)
CAS 2407516-83-8C20H22N10Na2O13P2
cGAMP disodium
C20H22N10Na2O13P2
Orb3173420
CAS 1951464-78-0C20H21F2N9O11P2
2-Propenoic acid, 2-methyl-, homopolymer, ester with 1,2,3-propanetriol
CAS 146126-21-8C32H53N11O13P2
cGAMP disodium
C20H24N10Na2O13P2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=[PH]1OCC2OC(n3cnc4cncnc43)CC2O[PH](=O)OCC2OC(n3cnc4cncnc43)CC2O1](/scaffold/DKYGFCPFAYPPMQ-UHFFFAOYSA-N/structure.svg)
![Scaffold O=c1[nH]cnc2c1ncn2C1CC2O[PH](=O)OCC3OC(n4cnc5c(=O)[nH]cnc54)CC3O[PH](=O)OCC2O1](/scaffold/RDQWPYNRYJEOPV-UHFFFAOYSA-N/structure.svg)