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Murcko scaffold

Ring system with 2 rings and 9 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
10
With full pages
2
Scaffold SMILES

C1=CC2COC=CC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=CC2COC=CC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Aucubigenin chemical structure, C9H12O4, CAS 64274-28-8
Aucubigenin
CAS 64274-28-8C9H12O4
(+)-Genipin chemical structure, C11H14O5, CAS 6902-77-8
(+)-Genipin
CAS 6902-77-8C11H14O5
Methyl (4aS,7aS)-7-formyl-1-hydroxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate chemical structure, C11H12O5, CAS 224177-02-0
Methyl (4aS,7aS)-7-formyl-1-hydroxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
CAS 224177-02-0C11H12O5
(1S,4AS,7aS)-methyl 1-((tert-butyldimethylsilyl)oxy)-7-(((tert-butyldimethylsilyl)oxy)methyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate chemical structure, C23H42O5Si2, CAS 122616-17-5
(1S,4AS,7aS)-methyl 1-((tert-butyldimethylsilyl)oxy)-7-(((tert-butyldimethylsilyl)oxy)methyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
CAS 122616-17-5C23H42O5Si2
(1S,4AS,7aS)-methyl 1-((tert-butyldimethylsilyl)oxy)-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate chemical structure, C17H28O5Si, CAS 116287-88-8
(1S,4AS,7aS)-methyl 1-((tert-butyldimethylsilyl)oxy)-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
CAS 116287-88-8C17H28O5Si
(1R,4aS,7aS)-Methyl 7-(hydroxymethyl)-1-methoxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate chemical structure, C12H16O5, CAS 69977-52-2
(1R,4aS,7aS)-Methyl 7-(hydroxymethyl)-1-methoxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
CAS 69977-52-2C12H16O5
Methyl 7-formyl-1-hydroxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate chemical structure, C11H12O5, CAS 142696-45-5
Methyl 7-formyl-1-hydroxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
CAS 142696-45-5C11H12O5
(1R,4aS,7aS)-Methyl 1-ethoxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate chemical structure, C13H18O5, CAS 1629668-62-7
(1R,4aS,7aS)-Methyl 1-ethoxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
CAS 1629668-62-7C13H18O5
(1R,4aS,7aS)-Methyl 7-(chloromethyl)-1-methoxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate chemical structure, C12H15ClO4, CAS 2162177-64-0
(1R,4aS,7aS)-Methyl 7-(chloromethyl)-1-methoxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
CAS 2162177-64-0C12H15ClO4
Methyl (1R,4aS,7aS)-7-formyl-1-hydroxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate chemical structure, C11H12O5, CAS 135910-36-0
Methyl (1R,4aS,7aS)-7-formyl-1-hydroxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
CAS 135910-36-0C11H12O5