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Murcko scaffold

Imidazo[5,1-d][1,2,3,5]tetrazin-4(1H)-one scaffold

24 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 10
Chemicals: 24
With full pages: 6

Scaffold SMILES

O=c1[nH]nnc2cncn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the Imidazo[5,1-d][1,2,3,5]tetrazin-4(1H)-one page

Murcko scaffold O=c1[nH]nnc2cncn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

Temozolomide chemical structure, C6H6N6O2, CAS 85622-93-1

CAS 85622-93-1C₆H₆N₆O₂

Mitozolomide chemical structure, C7H7ClN6O2, CAS 85622-95-3

CAS 85622-95-3C₇H₇ClN₆O₂

3-(2-Chloroethyl)-4-oxo-3H-imidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxylic acid chemical structure, C7H6ClN5O3, CAS 113942-32-8

3-(2-Chloroethyl)-4-oxo-3H-imidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxylic acid

CAS 113942-32-8C₇H₆ClN₅O₃

Ethazolastone chemical structure, C7H8N6O2, CAS 97716-74-0

CAS 97716-74-0C₇H₈N₆O₂

8-(N-Methyl)mitozolomide chemical structure, C8H9ClN6O2, CAS 85622-96-4

8-(N-Methyl)mitozolomide

CAS 85622-96-4C₈H₉ClN₆O₂

8-(N,N-Dimethyl)mitozolomide chemical structure, C9H11ClN6O2, CAS 85623-00-3

8-(N,N-Dimethyl)mitozolomide

CAS 85623-00-3C₉H₁₁ClN₆O₂

Temozolomide-d3 chemical structure, C6H6N6O2, CAS 208107-14-6

Temozolomide-d3

CAS 208107-14-6C₆H₆N₆O₂

Ethyl 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate chemical structure, C8H9N5O3, CAS 196806-14-1

Ethyl 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate

CAS 196806-14-1C₈H₉N₅O₃

3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carbonitrile chemical structure, C6H4N6O, CAS 114601-31-9

3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carbonitrile

CAS 114601-31-9C₆H₄N₆O

Propyl 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate chemical structure, C9H11N5O3, CAS 849939-96-4

Propyl 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate

CAS 849939-96-4C₉H₁₁N₅O₃

Methyl 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate chemical structure, C7H7N5O3, CAS 849939-95-3

Methyl 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate

CAS 849939-95-3C₇H₇N₅O₃

Temozolomide acid chemical structure, C6H5N5O3, CAS 113942-30-6

Temozolomide acid

CAS 113942-30-6C₆H₅N₅O₃

2-(8-Carbamoyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazin-3(4H)-yl)acetic acid chemical structure, C7H6N6O4, CAS 157466-98-3

2-(8-Carbamoyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazin-3(4H)-yl)acetic acid

CAS 157466-98-3C₇H₆N₆O₄

3-(2-Fluoroethyl)-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide chemical structure, C7H7FN6O2, CAS 1161826-19-2

3-(2-Fluoroethyl)-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide

CAS 1161826-19-2C₇H₇FN₆O₂

Methyl 3-(2-chloroethyl)-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate chemical structure, C8H8ClN5O3, CAS 113960-08-0

Methyl 3-(2-chloroethyl)-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate

CAS 113960-08-0C₈H₈ClN₅O₃

Ethyl 3-(2-chloroethyl)-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate chemical structure, C9H10ClN5O3, CAS 113942-48-6

Ethyl 3-(2-chloroethyl)-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate

CAS 113942-48-6C₉H₁₀ClN₅O₃

N-(2-Aminoethyl)-3-methyl-4-oxo-3H,4H-imidazo[4,3-D][1,2,3,5]tetrazine-8-carboxamide hydrochloride chemical structure, C8H12ClN7O2, CAS 1890937-80-0

N-(2-Aminoethyl)-3-methyl-4-oxo-3H,4H-imidazo[4,3-D][1,2,3,5]tetrazine-8-carboxamide hydrochloride

CAS 1890937-80-0C₈H₁₂ClN₇O₂

Imidazo[5,1-d][1,2,3,5]tetrazin-4(1H)-one chemical structure, C4H3N5O, CAS 121771-99-1

Imidazo[5,1-d][1,2,3,5]tetrazin-4(1H)-one

CAS 121771-99-1C₄H₃N₅O

4-Oxo-3H,4H-imidazo(4,3-d)(1,2,3,5)tetrazine-8-carboxamide chemical structure, C5H4N6O2, CAS 108030-65-5

4-Oxo-3H,4H-imidazo(4,3-d)(1,2,3,5)tetrazine-8-carboxamide

CAS 108030-65-5C₅H₄N₆O₂

8-Chloro-3-methylimidazo[5,1-d][1,2,3,5]tetrazin-4(3H)-one chemical structure, C5H4ClN5O, CAS 2260885-56-9

8-Chloro-3-methylimidazo[5,1-d][1,2,3,5]tetrazin-4(3H)-one

CAS 2260885-56-9C₅H₄ClN₅O

8-Bromo-3-methyl-imidazo[5,1-D][1,2,3,5]tetrazin-4-one chemical structure, C5H4BrN5O, CAS 2260886-17-5

8-Bromo-3-methyl-imidazo[5,1-D][1,2,3,5]tetrazin-4-one

CAS 2260886-17-5C₅H₄BrN₅O

Hexadecyl 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate chemical structure, C22H37N5O3, CAS 2761044-98-6

Hexadecyl 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate

CAS 2761044-98-6C₂₂H₃₇N₅O₃

3-(2-Fluoroethyl)-N-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide chemical structure, C8H9FN6O2, CAS 2920606-55-7

3-(2-Fluoroethyl)-N-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide

CAS 2920606-55-7C₈H₉FN₆O₂

4-Oxo-3-[2-(trifluoromethoxy)ethyl]imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide chemical structure, C8H7F3N6O3, CAS 3075414-82-0

4-Oxo-3-[2-(trifluoromethoxy)ethyl]imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide

CAS 3075414-82-0C₈H₇F₃N₆O₃