CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 23 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
10
With full pages
2
Scaffold SMILES

O=c1[nH]cc(-c2ccccc2Oc2ccccc2)c2cc[nH]c12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cc(-c2ccccc2Oc2ccccc2)c2cc[nH]c12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Mivebresib chemical structure, C22H19F2N3O4S, CAS 1445993-26-9
Mivebresib
CAS 1445993-26-9C22H19F2N3O4S
Ethyl 3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-phenoxybenzoate chemical structure, C23H20N2O4, CAS 1445992-74-4
Ethyl 3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-phenoxybenzoate
CAS 1445992-74-4C23H20N2O4
Orb2566767 chemical structure, C23H21N3O3, CAS 1445992-82-4
Orb2566767
CAS 1445992-82-4C23H21N3O3
1,6-Dihydro-6-methyl-4-[5-(methylsulfonyl)-2-phenoxyphenyl]-7H-pyrrolo[2,3-c]pyridin-7-one chemical structure, C21H18N2O4S, CAS 1445993-77-0
1,6-Dihydro-6-methyl-4-[5-(methylsulfonyl)-2-phenoxyphenyl]-7H-pyrrolo[2,3-c]pyridin-7-one
CAS 1445993-77-0C21H18N2O4S
PROTAC BRD4 ligand-3 chemical structure, C20H15F2N3O2, CAS 1445994-28-4
PROTAC BRD4 ligand-3
CAS 1445994-28-4C20H15F2N3O2
Ethyl 4-[2-(2,4-difluorophenoxy)-5-(methylsulfonyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxylate chemical structure, C24H20F2N2O6S, CAS 1446236-17-4
Ethyl 4-[2-(2,4-difluorophenoxy)-5-(methylsulfonyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxylate
CAS 1446236-17-4C24H20F2N2O6S
N-Ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl)-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo(2,3-c)pyridine-2-carboxamide chemical structure, C28H30FN3O4, CAS 2138861-99-9
N-Ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl)-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo(2,3-c)pyridine-2-carboxamide
CAS 2138861-99-9C28H30FN3O4
N-[3-(6-Methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-(3-prop-2-ynoxyphenoxy)phenyl]ethanesulfonamide chemical structure, C25H23N3O5S, CAS 2257497-24-6
N-[3-(6-Methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-(3-prop-2-ynoxyphenoxy)phenyl]ethanesulfonamide
CAS 2257497-24-6C25H23N3O5S
Repibresib chemical structure, C20H16N2O3, CAS 2523199-93-9
Repibresib
CAS 2523199-93-9C20H16N2O3
Methyl 4-[5-(2-hydroxypropan-2-yl)-2-phenoxyphenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxylate chemical structure, C25H24N2O5, CAS 3032781-39-5
Methyl 4-[5-(2-hydroxypropan-2-yl)-2-phenoxyphenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxylate
CAS 3032781-39-5C25H24N2O5