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Screening compounds

Mivebresib

Also known as ABBV-075, N-(4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide, Ethanesulfonamide, N-[4-(2,4-difluorophenoxy)-3-(6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]-

CAS 1445993-26-9Formula C22H19F2N3O4SMolar mass 459.47 g/mol
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Mivebresib chemical structure, C22H19F2N3O4S, CAS 1445993-26-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1445993-26-9
Formula
C22H19F2N3O4S
Molar mass
459.47 g/mol
HS code
293590
Category
Screening compounds

What is Mivebresib?

Plain description, key identifiers and synonyms

Mivebresib is an inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity. Upon administration, mivebresib binds to the acetyl-lysine binding site of BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones. This disrupts chromatin remodeling, prevents the expression of certain growth-promoting genes, and leads to an inhibition of cell growth in susceptible tumors.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]ethanesulfonamide
CAS number
1445993-26-9
Molecular formula
C22H19F2N3O4S
UNII
VR86R11J7J
MDL number
MFCD30377200
InChIKey
RDONXGFGWSSFMY-UHFFFAOYSA-N
InChI
InChI=1S/C22H19F2N3O4S/c1-3-32(29,30)26-14-5-7-19(31-20-6-4-13(23)10-18(20)24)16(11-14)17-12-27(2)22(28)21-15(17)8-9-25-21/h4-12,25-26H,3H2,1-2H3
SMILES (canonical and isomeric)
CCS(=O)(=O)NC1=CC(=C(C=C1)OC2=C(C=C(C=C2)F)F)C3=CN(C(=O)C4=C3C=CN4)C

Synonyms

  • ABBV-075
  • N-(4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide
  • Ethanesulfonamide, N-[4-(2,4-difluorophenoxy)-3-(6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]-
  • N-[4-(2,4-Difluorophenoxy)-3-(6-Methyl-7-Oxo-6,7-Dihydro-1h-Pyrrolo[2,3-C]pyridin-4-Yl)phenyl]ethanesulfonamide
  • Ethanesulfonamide, N-(4-(2,4-difluorophenoxy)-3-(6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo(2,3-C)pyridin-4-yl)phenyl)-
  • mivebresibum
  • N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo(2,3-C)pyridin-4-yl)phenyl)ethanesulfonamide
  • Mivebresib(ABBV-075
  • N-[4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]ethanesulfonamide
  • Mivebresib (ABBV-075)
  • ABBV 075
  • N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro- 1H-pyrrolo(2,3-C)pyridin-4-yl)phenyl)ethanesulfonamide
  • Mivebresib (USAN/INN)
  • Mivebresib(ABBV-075?
  • Mivebresib, ABBV-075
  • Mivebresib, 98% (HPLC)
  • N-[4-(2,4-difluoropheno
  • Example 36
  • N-[4-(2,4-difluorophenoxy)-3-{6-methyl-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-4-yl}phenyl]ethane-1-sulfonamide
  • US9296741, 36

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
459.47 g/molcalc.
Exact mass
459.1064 Dacalc.
LogP (octanol/water)
4.37calc.
Topological polar surface area
93.19 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
32calc.
Rings
4calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.14calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1[nH]cc(-c2ccccc2Oc2ccccc2)c2cc[nH]c12

O=c1[nH]cc(-c2ccccc2Oc2ccccc2)c2cc[nH]c12

4 rings, 23 atoms.

9 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Mivebresib suppliers

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All 3 suppliers

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Where suppliers are based

3 suppliers in 3 countries

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Mivebresib price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antifibrotic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mivebresib is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Mivebresib is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mivebresib, based on the data on this page

What is Mivebresib?

Mivebresib is an inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with potential antineoplastic activity. Upon administration, mivebresib binds to the acetyl-lysine binding site of BRD-containing protein(s), thereby preventing the interaction between those proteins and acetylated histones.

What is the CAS number of Mivebresib?

The CAS registry number of Mivebresib is 1445993-26-9.

What is the molecular formula and weight of Mivebresib?

The molecular formula of Mivebresib is C22H19F2N3O4S and its molar mass is 459.47 g/mol.

What is Mivebresib used for?

Known uses and roles of Mivebresib include building blocks in research and laboratory, screening compounds in research and laboratory, antifibrotic agent and pharmaceutical.

Is Mivebresib hazardous?

No GHS hazard classification for Mivebresib is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Mivebresib?

Mivebresib is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Mivebresib?

CompoundList lists 3 suppliers of Mivebresib in China, Japan and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Mivebresib?

Suppliers quote Mivebresib on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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