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Murcko scaffold

1,4-Bis(phenylsulfonyl)-1,4-diazepane scaffold

69 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
69
With full pages
7
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Bis(phenylsulfonyl)-1,4-diazepane page
Murcko scaffold O=S(=O)(c1ccccc1)N1CCCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 69 chemicals

1,4-Bis(phenylsulfonyl)-1,4-diazepane chemical structure, C17H20N2O4S2, CAS 5451-44-5
1,4-Bis(phenylsulfonyl)-1,4-diazepane
CAS 5451-44-5C17H20N2O4S2
1,4-Ditosyl-1,4-diazepane chemical structure, C19H24N2O4S2, CAS 5769-35-7
1,4-Ditosyl-1,4-diazepane
CAS 5769-35-7C19H24N2O4S2
1,4-Bis[(4-tert-butylphenyl)sulfonyl]-1,4-diazepane chemical structure, C25H36N2O4S2, CAS 522598-18-1
1,4-Bis[(4-tert-butylphenyl)sulfonyl]-1,4-diazepane
CAS 522598-18-1C25H36N2O4S2
1,4-Bis[(5-fluoro-2-methoxyphenyl)sulfonyl]-1,4-diazepane chemical structure, C19H22F2N2O6S2, CAS 700857-43-8
1,4-Bis[(5-fluoro-2-methoxyphenyl)sulfonyl]-1,4-diazepane
CAS 700857-43-8C19H22F2N2O6S2
1,4-Bis(4-methoxy-2,3-dimethylbenzenesulfonyl)-1,4-diazepane chemical structure, C23H32N2O6S2, CAS 695175-79-2
1,4-Bis(4-methoxy-2,3-dimethylbenzenesulfonyl)-1,4-diazepane
CAS 695175-79-2C23H32N2O6S2
1,4-Bis(2,4-dimethylbenzenesulfonyl)-1,4-diazepane chemical structure, C21H28N2O4S2, CAS 333311-19-6
1,4-Bis(2,4-dimethylbenzenesulfonyl)-1,4-diazepane
CAS 333311-19-6C21H28N2O4S2
1,4-Bis[(2,3,4,5,6-pentamethylphenyl)sulfonyl]-1,4-diazepane chemical structure, C27H40N2O4S2, CAS 438237-19-5
1,4-Bis[(2,3,4,5,6-pentamethylphenyl)sulfonyl]-1,4-diazepane
CAS 438237-19-5C27H40N2O4S2
1,4-Bis[(2,5-dimethoxyphenyl)sulfonyl]-1,4-diazepane chemical structure, C21H28N2O8S2, CAS 438227-77-1
1,4-Bis[(2,5-dimethoxyphenyl)sulfonyl]-1,4-diazepane
CAS 438227-77-1C21H28N2O8S2
1,4-Bis[(4-fluorophenyl)sulfonyl]-1,4-diazepane chemical structure, C17H18F2N2O4S2, CAS 438473-28-0
1,4-Bis[(4-fluorophenyl)sulfonyl]-1,4-diazepane
CAS 438473-28-0C17H18F2N2O4S2
1,4-Bis[(5-chloro-2-methoxyphenyl)sulfonyl]-1,4-diazepane chemical structure, C19H22Cl2N2O6S2, CAS 309741-68-2
1,4-Bis[(5-chloro-2-methoxyphenyl)sulfonyl]-1,4-diazepane
CAS 309741-68-2C19H22Cl2N2O6S2
1,4-Bis[(4-ethylphenyl)sulfonyl]-1,4-diazepane chemical structure, C21H28N2O4S2, CAS 309741-70-6
1,4-Bis[(4-ethylphenyl)sulfonyl]-1,4-diazepane
CAS 309741-70-6C21H28N2O4S2
1,4-Bis[(2,4-dichloro-5-methylphenyl)sulfonyl]-1,4-diazepane chemical structure, C19H20Cl4N2O4S2, CAS 457961-01-2
1,4-Bis[(2,4-dichloro-5-methylphenyl)sulfonyl]-1,4-diazepane
CAS 457961-01-2C19H20Cl4N2O4S2
1,4-Bis[(3,4-dimethylphenyl)sulfonyl]-1,4-diazepane chemical structure, C21H28N2O4S2, CAS 333311-18-5
1,4-Bis[(3,4-dimethylphenyl)sulfonyl]-1,4-diazepane
CAS 333311-18-5C21H28N2O4S2
1,4-Bis[(4-methoxyphenyl)sulfonyl]-1,4-diazepane chemical structure, C19H24N2O6S2, CAS 548471-77-8
1,4-Bis[(4-methoxyphenyl)sulfonyl]-1,4-diazepane
CAS 548471-77-8C19H24N2O6S2
1,4-Bis((4-chlorophenyl)sulfonyl)-1,4-diazepane chemical structure, C17H18Cl2N2O4S2, CAS 332389-14-7
1,4-Bis((4-chlorophenyl)sulfonyl)-1,4-diazepane
CAS 332389-14-7C17H18Cl2N2O4S2
1,4-Bis(4-bromobenzenesulfonyl)-1,4-diazepane chemical structure, C17H18Br2N2O4S2, CAS 332389-15-8
1,4-Bis(4-bromobenzenesulfonyl)-1,4-diazepane
CAS 332389-15-8C17H18Br2N2O4S2
1,4-Bis[(4-ethoxyphenyl)sulfonyl]-1,4-diazepane chemical structure, C21H28N2O6S2, CAS 433688-60-9
1,4-Bis[(4-ethoxyphenyl)sulfonyl]-1,4-diazepane
CAS 433688-60-9C21H28N2O6S2
1,4-Bis[(4-methoxy-3-methylphenyl)sulfonyl]-1,4-diazepane chemical structure, C21H28N2O6S2, CAS 433965-96-9
1,4-Bis[(4-methoxy-3-methylphenyl)sulfonyl]-1,4-diazepane
CAS 433965-96-9C21H28N2O6S2
1,4-Bis[(4-methoxy-2-methylphenyl)sulfonyl]-1,4-diazepane chemical structure, C21H28N2O6S2, CAS 433695-17-1
1,4-Bis[(4-methoxy-2-methylphenyl)sulfonyl]-1,4-diazepane
CAS 433695-17-1C21H28N2O6S2
1,4-Bis(2,3,5,6-tetramethylbenzenesulfonyl)-1,4-diazepane chemical structure, C25H36N2O4S2, CAS 691369-87-6
1,4-Bis(2,3,5,6-tetramethylbenzenesulfonyl)-1,4-diazepane
CAS 691369-87-6C25H36N2O4S2
1,4-Bis(5-bromo-2-methoxybenzenesulfonyl)-1,4-diazepane chemical structure, C19H22Br2N2O6S2, CAS 447410-66-4
1,4-Bis(5-bromo-2-methoxybenzenesulfonyl)-1,4-diazepane
CAS 447410-66-4C19H22Br2N2O6S2
1,4-Bis[(4-chloro-2,5-dimethoxyphenyl)sulfonyl]-1,4-diazepane chemical structure, C21H26Cl2N2O8S2, CAS 700851-23-6
1,4-Bis[(4-chloro-2,5-dimethoxyphenyl)sulfonyl]-1,4-diazepane
CAS 700851-23-6C21H26Cl2N2O8S2
N-[4-[[4-(4-Acetamidophenyl)sulfonyl-1,4-diazepan-1-yl]sulfonyl]phenyl]acetamide chemical structure, C21H26N4O6S2, CAS 547722-10-1
N-[4-[[4-(4-Acetamidophenyl)sulfonyl-1,4-diazepan-1-yl]sulfonyl]phenyl]acetamide
CAS 547722-10-1C21H26N4O6S2
1,4-Bis(2,3,4-trimethylbenzenesulfonyl)-1,4-diazepane chemical structure, C23H32N2O4S2, CAS 433948-21-1
1,4-Bis(2,3,4-trimethylbenzenesulfonyl)-1,4-diazepane
CAS 433948-21-1C23H32N2O4S2