Murcko scaffold
Ring system with 3 rings and 20 atoms
22 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 20
- Chemicals
- 22
- With full pages
- 4
Scaffold SMILES
c1ccc(CN2CCC(N3CCCCCC3)CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 22 of 22 chemicals
![1-[1-(3-Methoxybenzyl)piperidin-4-yl]azepane chemical structure, C19H30N2O, CAS 431981-62-3](/s/BJYPEFIGQLAQDL-UHFFFAOYSA-N.svg)
1-[1-(3-Methoxybenzyl)piperidin-4-yl]azepane
CAS 431981-62-3C19H30N2O
![1-[1-(4-Methoxybenzyl)-4-piperidinyl]azepane chemical structure, C19H30N2O, CAS 432021-85-7](/s/ODTQWBZBOYELLN-UHFFFAOYSA-N.svg)
1-[1-(4-Methoxybenzyl)-4-piperidinyl]azepane
CAS 432021-85-7C19H30N2O
![1-[1-(2,3-Dimethoxybenzyl)piperidin-4-yl]azepane chemical structure, C20H32N2O2, CAS 432009-58-0](/s/IAKOXWWDAONPLP-UHFFFAOYSA-N.svg)
1-[1-(2,3-Dimethoxybenzyl)piperidin-4-yl]azepane
CAS 432009-58-0C20H32N2O2
![1-[1-(3,4-Dimethoxybenzyl)-4-piperidinyl]azepane chemical structure, C20H32N2O2, CAS 431980-55-1](/s/BSRWGPMRYOYXDM-UHFFFAOYSA-N.svg)
1-[1-(3,4-Dimethoxybenzyl)-4-piperidinyl]azepane
CAS 431980-55-1C20H32N2O2
![1-[1-(4-Ethoxybenzyl)-4-piperidinyl]azepane chemical structure, C20H32N2O, CAS 431982-68-2](/s/ZVFMPKKXRCMOCK-UHFFFAOYSA-N.svg)
1-[1-(4-Ethoxybenzyl)-4-piperidinyl]azepane
CAS 431982-68-2C20H32N2O
![1-[1-(4-Fluorobenzyl)piperidin-4-yl]azepane chemical structure, C18H27FN2, CAS 431939-58-1](/s/PKGIIVXLSMUQAR-UHFFFAOYSA-N.svg)
1-[1-(4-Fluorobenzyl)piperidin-4-yl]azepane
CAS 431939-58-1C18H27FN2
![1-{1-[4-(Methylsulfanyl)benzyl]piperidin-4-yl}azepane chemical structure, C19H30N2S, CAS 432002-45-4](/s/FGOJRDLAYKJAMQ-UHFFFAOYSA-N.svg)
1-{1-[4-(Methylsulfanyl)benzyl]piperidin-4-yl}azepane
CAS 432002-45-4C19H30N2S
![1-[1-(2,4-Dimethoxybenzyl)piperidin-4-yl]azepane chemical structure, C20H32N2O2, CAS 431934-00-8](/s/AZJUPOOOQKUGQB-UHFFFAOYSA-N.svg)
1-[1-(2,4-Dimethoxybenzyl)piperidin-4-yl]azepane
CAS 431934-00-8C20H32N2O2
![1-[1-(4-Chlorobenzyl)piperidin-4-yl]azepane chemical structure, C18H27ClN2, CAS 431933-11-8](/s/KJQAKQHALZAGLE-UHFFFAOYSA-N.svg)
1-[1-(4-Chlorobenzyl)piperidin-4-yl]azepane
CAS 431933-11-8C18H27ClN2
![1-[1-[(3-Nitrophenyl)methyl]piperidin-4-yl]azepane chemical structure, C18H27N3O2, CAS 431996-27-9](/s/MLSZMPZIQOYRLC-UHFFFAOYSA-N.svg)
1-[1-[(3-Nitrophenyl)methyl]piperidin-4-yl]azepane
CAS 431996-27-9C18H27N3O2
![1-[1-(2,5-Dimethoxybenzyl)piperidin-4-yl]azepane chemical structure, C20H32N2O2, CAS 432005-07-7](/s/CLLAAYNFTDRUEM-UHFFFAOYSA-N.svg)
1-[1-(2,5-Dimethoxybenzyl)piperidin-4-yl]azepane
CAS 432005-07-7C20H32N2O2
![1-[1-[(2-Nitrophenyl)methyl]piperidin-4-yl]azepane chemical structure, C18H27N3O2, CAS 432009-23-9](/s/FDCAGZZEHFYTFX-UHFFFAOYSA-N.svg)
1-[1-[(2-Nitrophenyl)methyl]piperidin-4-yl]azepane
CAS 432009-23-9C18H27N3O2
![1-[1-(3-Fluorobenzyl)piperidin-4-yl]azepane chemical structure, C18H27FN2, CAS 432010-67-8](/s/FQRQOXMOFWBSPL-UHFFFAOYSA-N.svg)
1-[1-(3-Fluorobenzyl)piperidin-4-yl]azepane
CAS 432010-67-8C18H27FN2
![1-[1-(3-Chlorobenzyl)piperidin-4-yl]azepane chemical structure, C18H27ClN2, CAS 432016-82-5](/s/OKJOUUDDHLNKIV-UHFFFAOYSA-N.svg)
1-[1-(3-Chlorobenzyl)piperidin-4-yl]azepane
CAS 432016-82-5C18H27ClN2
![1-[1-(2-Chlorobenzyl)piperidin-4-yl]azepane chemical structure, C18H27ClN2, CAS 431985-49-8](/s/RWTGUBBBINUODQ-UHFFFAOYSA-N.svg)
1-[1-(2-Chlorobenzyl)piperidin-4-yl]azepane
CAS 431985-49-8C18H27ClN2
![1-{1-[2-(Trifluoromethyl)benzyl]piperidin-4-yl}azepane chemical structure, C19H27F3N2, CAS 432014-45-4](/s/YMRQKKZQDMOHPP-UHFFFAOYSA-N.svg)
1-{1-[2-(Trifluoromethyl)benzyl]piperidin-4-yl}azepane
CAS 432014-45-4C19H27F3N2
![1-[1-[(4-Nitrophenyl)methyl]piperidin-4-yl]azepane chemical structure, C18H27N3O2, CAS 432021-03-9](/s/RHMUINAFPFUUFL-UHFFFAOYSA-N.svg)
1-[1-[(4-Nitrophenyl)methyl]piperidin-4-yl]azepane
CAS 432021-03-9C18H27N3O2
![1-[1-(4-Methylbenzyl)piperidin-4-yl]azepane chemical structure, C19H30N2, CAS 432021-69-7](/s/IGHXQGWOGRFIGM-UHFFFAOYSA-N.svg)
1-[1-(4-Methylbenzyl)piperidin-4-yl]azepane
CAS 432021-69-7C19H30N2
![1-[1-(4-Ethylbenzyl)piperidin-4-yl]azepane chemical structure, C20H32N2, CAS 431939-89-8](/s/DZXVFHWLACRDDI-UHFFFAOYSA-N.svg)
1-[1-(4-Ethylbenzyl)piperidin-4-yl]azepane
CAS 431939-89-8C20H32N2
![1-[1-[(4-Bromophenyl)methyl]piperidin-4-yl]azepane chemical structure, C18H27BrN2, CAS 432003-97-9](/s/PBOBJZBOPBXFEI-UHFFFAOYSA-N.svg)
1-[1-[(4-Bromophenyl)methyl]piperidin-4-yl]azepane
CAS 432003-97-9C18H27BrN2
![1-[1-(3-Bromobenzyl)piperidin-4-yl]azepane chemical structure, C18H27BrN2, CAS 432019-17-5](/s/PLLSWSXUKRNSES-UHFFFAOYSA-N.svg)
1-[1-(3-Bromobenzyl)piperidin-4-yl]azepane
CAS 432019-17-5C18H27BrN2
![2-[[4-(Azepan-1-yl)piperidin-1-yl]methyl]-4-bromophenol chemical structure, C18H27BrN2O, CAS 431906-72-8](/s/VCWPPAHWZDBLEQ-UHFFFAOYSA-N.svg)
2-[[4-(Azepan-1-yl)piperidin-1-yl]methyl]-4-bromophenol
CAS 431906-72-8C18H27BrN2O
Related scaffolds
Same ring framework with different atoms or bond orders
