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Murcko scaffold

1-[1-(Benzenesulfonyl)piperidin-4-yl]azepane scaffold

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
6
With full pages
4
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCC(N2CCCCCC2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-[1-(Benzenesulfonyl)piperidin-4-yl]azepane page
Murcko scaffold O=S(=O)(c1ccccc1)N1CCC(N2CCCCCC2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

1-[1-(4-Chlorophenyl)sulfonylpiperidin-4-yl]azepane chemical structure, C17H25ClN2O2S, CAS 432002-32-9
1-[1-(4-Chlorophenyl)sulfonylpiperidin-4-yl]azepane
CAS 432002-32-9C17H25ClN2O2S
1-[1-(4-Methylphenyl)sulfonylpiperidin-4-yl]azepane chemical structure, C18H28N2O2S, CAS 432000-35-6
1-[1-(4-Methylphenyl)sulfonylpiperidin-4-yl]azepane
CAS 432000-35-6C18H28N2O2S
1-[1-(Benzenesulfonyl)piperidin-4-yl]azepane chemical structure, C17H26N2O2S, CAS 431938-83-9
1-[1-(Benzenesulfonyl)piperidin-4-yl]azepane
CAS 431938-83-9C17H26N2O2S
1-{1-[(4-Fluorophenyl)sulfonyl]-4-piperidinyl}azepane chemical structure, C17H25FN2O2S, CAS 675150-62-6
1-{1-[(4-Fluorophenyl)sulfonyl]-4-piperidinyl}azepane
CAS 675150-62-6C17H25FN2O2S
1-[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]azepane chemical structure, C18H28N2O3S, CAS 431917-57-6
1-[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]azepane
CAS 431917-57-6C18H28N2O3S
N-[4-[4-(Azepan-1-yl)piperidin-1-yl]sulfonylphenyl]acetamide chemical structure, C19H29N3O3S, CAS 792926-86-4
N-[4-[4-(Azepan-1-yl)piperidin-1-yl]sulfonylphenyl]acetamide
CAS 792926-86-4C19H29N3O3S