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Murcko scaffold

Ring system with 3 rings and 24 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(CNc1ccccc1)Nc1ccccc1C(=O)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNc1ccccc1)Nc1ccccc1C(=O)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-(2-Methoxy-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide chemical structure, C21H25N3O5S, CAS 446050-47-1
2-(2-Methoxy-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide
CAS 446050-47-1C21H25N3O5S
2-(5-Chloro-2-methoxy-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide chemical structure, C21H24ClN3O5S, CAS 446056-79-7
2-(5-Chloro-2-methoxy-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide
CAS 446056-79-7C21H24ClN3O5S
2-(3-Methoxy-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide chemical structure, C21H25N3O5S, CAS 446039-85-6
2-(3-Methoxy-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide
CAS 446039-85-6C21H25N3O5S
2-(N-Methylsulfonyl-3-nitroanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide chemical structure, C20H22N4O6S, CAS 446047-76-3
2-(N-Methylsulfonyl-3-nitroanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide
CAS 446047-76-3C20H22N4O6S
2-(3-Fluoro-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide chemical structure, C20H22FN3O4S, CAS 694496-69-0
2-(3-Fluoro-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide
CAS 694496-69-0C20H22FN3O4S
2-(2-Fluoro-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide chemical structure, C20H22FN3O4S, CAS 462060-46-4
2-(2-Fluoro-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide
CAS 462060-46-4C20H22FN3O4S
2-(2,3-Dichloro-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide chemical structure, C20H21Cl2N3O4S, CAS 527748-63-6
2-(2,3-Dichloro-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]acetamide
CAS 527748-63-6C20H21Cl2N3O4S
2-(3,5-Dimethyl-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]propanamide chemical structure, C23H29N3O4S, CAS 1033587-80-2
2-(3,5-Dimethyl-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]propanamide
CAS 1033587-80-2C23H29N3O4S
2-(2,5-Dimethyl-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]propanamide chemical structure, C23H29N3O4S, CAS 1094101-49-1
2-(2,5-Dimethyl-N-methylsulfonylanilino)-N-[2-(pyrrolidine-1-carbonyl)phenyl]propanamide
CAS 1094101-49-1C23H29N3O4S