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Murcko scaffold

5,6-Dihydrofuro[2,3-d]pyrimidine scaffold

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
17
With full pages
3
Scaffold SMILES

c1ncc2c(n1)OCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6-Dihydrofuro[2,3-d]pyrimidine page
Murcko scaffold c1ncc2c(n1)OCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

4-Methyl-5,6-dihydrofuro[2,3-d]pyrimidin-2-yl carbamimidothioate chemical structure, C8H10N4OS, CAS 5118-01-4
4-Methyl-5,6-dihydrofuro[2,3-d]pyrimidin-2-yl carbamimidothioate
CAS 5118-01-4C8H10N4OS
6-(Bromomethyl)-4-methyl-2-methylsulfanyl-5,6-dihydrofuro[2,3-d]pyrimidine chemical structure, C9H11BrN2OS, CAS 120478-12-8
6-(Bromomethyl)-4-methyl-2-methylsulfanyl-5,6-dihydrofuro[2,3-d]pyrimidine
CAS 120478-12-8C9H11BrN2OS
4-Methyl-5,6-dihydrofuro[2,3-d]pyrimidin-2-amine chemical structure, C7H9N3O, CAS 21585-10-4
4-Methyl-5,6-dihydrofuro[2,3-d]pyrimidin-2-amine
CAS 21585-10-4C7H9N3O
6-(Bromomethyl)-2,4-dimethyl-5,6-dihydrofuro[2,3-d]pyrimidine chemical structure, C9H11BrN2O, CAS 78304-56-0
6-(Bromomethyl)-2,4-dimethyl-5,6-dihydrofuro[2,3-d]pyrimidine
CAS 78304-56-0C9H11BrN2O
6-(Bromomethyl)-2,4-dimethyl-5,6-dihydrofuro[2,3-d]pyrimidine hydrobromide chemical structure, C9H12Br2N2O, CAS 78304-55-9
6-(Bromomethyl)-2,4-dimethyl-5,6-dihydrofuro[2,3-d]pyrimidine hydrobromide
CAS 78304-55-9C9H12Br2N2O
4-Methyl-5,6-dihydrofuro[2,3-d]pyrimidin-2-yl carbamimidothioate--hydrogen bromide (1/1) chemical structure, C8H11BrN4OS, CAS 78831-58-0
4-Methyl-5,6-dihydrofuro[2,3-d]pyrimidin-2-yl carbamimidothioate--hydrogen bromide (1/1)
CAS 78831-58-0C8H11BrN4OS
4-Chloro-5H,6H-furo[2,3-d]pyrimidin-2-amine chemical structure, C6H6ClN3O, CAS 76881-47-5
4-Chloro-5H,6H-furo[2,3-d]pyrimidin-2-amine
CAS 76881-47-5C6H6ClN3O
4-Methoxy-2-(methylsulfonyl)-5,6-dihydrofuro[2,3-d]pyrimidine chemical structure, C8H10N2O4S, CAS 143323-12-0
4-Methoxy-2-(methylsulfonyl)-5,6-dihydrofuro[2,3-d]pyrimidine
CAS 143323-12-0C8H10N2O4S
5,6-Dihydrofuro[2,3-d]pyrimidin-2-amine chemical structure, C6H7N3O, CAS 88513-35-3
5,6-Dihydrofuro[2,3-d]pyrimidin-2-amine
CAS 88513-35-3C6H7N3O
5,6-Dihydrofuro[2,3-d]pyrimidine chemical structure, C6H6N2O, CAS 23956-14-1
5,6-Dihydrofuro[2,3-d]pyrimidine
CAS 23956-14-1C6H6N2O
2,4-Dichloro-5H,6H-furo(2,3-d)pyrimidine chemical structure, C6H4Cl2N2O, CAS 1823731-18-5
2,4-Dichloro-5H,6H-furo(2,3-d)pyrimidine
CAS 1823731-18-5C6H4Cl2N2O
4-Chloro-5H,6H-furo[2,3-d]pyrimidine chemical structure, C6H5ClN2O, CAS 1378831-86-7
4-Chloro-5H,6H-furo[2,3-d]pyrimidine
CAS 1378831-86-7C6H5ClN2O
4-Chloro-2-methyl-5H,6H-furo[2,3-d]pyrimidine chemical structure, C7H7ClN2O, CAS 1514239-62-3
4-Chloro-2-methyl-5H,6H-furo[2,3-d]pyrimidine
CAS 1514239-62-3C7H7ClN2O
2-Methyl-5,6-dihydrofuro[2,3-d]pyrimidine chemical structure, C7H8N2O, CAS 53750-89-3
2-Methyl-5,6-dihydrofuro[2,3-d]pyrimidine
CAS 53750-89-3C7H8N2O
2-Chloro-5H,6H-furo[2,3-d]pyrimidin-4-amine chemical structure, C6H6ClN3O, CAS 2387299-41-2
2-Chloro-5H,6H-furo[2,3-d]pyrimidin-4-amine
CAS 2387299-41-2C6H6ClN3O
2,4-Bis(methylsulfanyl)-5H,6H-furo[2,3-d]pyrimidine chemical structure, C8H10N2OS2, CAS 2680534-20-5
2,4-Bis(methylsulfanyl)-5H,6H-furo[2,3-d]pyrimidine
CAS 2680534-20-5C8H10N2OS2
4-Chloro-2-(chloromethyl)-5H,6H-furo[2,3-d]pyrimidine chemical structure, C7H6Cl2N2O, CAS 3083504-86-0
4-Chloro-2-(chloromethyl)-5H,6H-furo[2,3-d]pyrimidine
CAS 3083504-86-0C7H6Cl2N2O