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Murcko scaffold

1-Phenylmethanesulfonylpiperazine scaffold

109 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 16
Chemicals: 109
With full pages: 5

Scaffold SMILES

O=S(=O)(Cc1ccccc1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-Phenylmethanesulfonylpiperazine page

Murcko scaffold O=S(=O)(Cc1ccccc1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 109 chemicals

1-Benzylsulfonyl-4-methylpiperazine chemical structure, C12H18N2O2S, CAS 331847-66-6

1-Benzylsulfonyl-4-methylpiperazine

CAS 331847-66-6C₁₂H₁₈N₂O₂S

1-Benzylsulfonyl-4-ethylpiperazine chemical structure, C13H20N2O2S, CAS 403670-03-1

1-Benzylsulfonyl-4-ethylpiperazine

CAS 403670-03-1C₁₃H₂₀N₂O₂S

2-(4-Benzylsulfonylpiperazin-1-yl)ethanol chemical structure, C13H20N2O3S, CAS 331847-67-7

2-(4-Benzylsulfonylpiperazin-1-yl)ethanol

CAS 331847-67-7C₁₃H₂₀N₂O₃S

1-Benzylsulfonyl-4-ethylsulfonylpiperazine chemical structure, C13H20N2O4S2, CAS 428851-46-1

1-Benzylsulfonyl-4-ethylsulfonylpiperazine

CAS 428851-46-1C₁₃H₂₀N₂O₄S₂

1-Benzylsulfonyl-4-propan-2-ylpiperazine chemical structure, C14H22N2O2S, CAS 792926-74-0

1-Benzylsulfonyl-4-propan-2-ylpiperazine

CAS 792926-74-0C₁₄H₂₂N₂O₂S

1-Phenylmethanesulfonylpiperazine chemical structure, C11H16N2O2S, CAS 186412-62-4

1-Phenylmethanesulfonylpiperazine

CAS 186412-62-4C₁₁H₁₆N₂O₂S

1-[(2-Chlorophenyl)methylsulfonyl]-4-ethylpiperazine chemical structure, C13H19ClN2O2S, CAS 838868-66-9

1-[(2-Chlorophenyl)methylsulfonyl]-4-ethylpiperazine

CAS 838868-66-9C₁₃H₁₉ClN₂O₂S

1-[(2-Chlorophenyl)methylsulfonyl]-4-methylpiperazine chemical structure, C12H17ClN2O2S, CAS 827621-64-7

1-[(2-Chlorophenyl)methylsulfonyl]-4-methylpiperazine

CAS 827621-64-7C₁₂H₁₇ClN₂O₂S

1-(4-Benzylsulfonylpiperazin-1-yl)-3-methylbutan-1-one chemical structure, C16H24N2O3S, CAS 519005-82-4

1-(4-Benzylsulfonylpiperazin-1-yl)-3-methylbutan-1-one

CAS 519005-82-4C₁₆H₂₄N₂O₃S

2-Chloro-1-(4-phenylmethanesulfonylpiperazin-1-yl)ethan-1-one chemical structure, C13H17ClN2O3S, CAS 221289-97-0

2-Chloro-1-(4-phenylmethanesulfonylpiperazin-1-yl)ethan-1-one

CAS 221289-97-0C₁₃H₁₇ClN₂O₃S

1-Phenylmethanesulfonyl-4-(prop-2-YN-1-yl)piperazine chemical structure, C14H18N2O2S, CAS 923693-77-0

1-Phenylmethanesulfonyl-4-(prop-2-YN-1-yl)piperazine

CAS 923693-77-0C₁₄H₁₈N₂O₂S

1-[(2,6-Dichlorobenzyl)sulfonyl]-4-ethylpiperazine chemical structure, C13H18Cl2N2O2S, CAS 948531-83-7

1-[(2,6-Dichlorobenzyl)sulfonyl]-4-ethylpiperazine

CAS 948531-83-7C₁₃H₁₈Cl₂N₂O₂S

1-[(3-Chlorobenzyl)sulfonyl]-4-ethylpiperazine chemical structure, C13H19ClN2O2S, CAS 950257-67-7

1-[(3-Chlorobenzyl)sulfonyl]-4-ethylpiperazine

CAS 950257-67-7C₁₃H₁₉ClN₂O₂S

Ethyl 4-[(4-fluorobenzyl)sulfonyl]piperazine-1-carboxylate chemical structure, C14H19FN2O4S, CAS 950234-52-3

Ethyl 4-[(4-fluorobenzyl)sulfonyl]piperazine-1-carboxylate

CAS 950234-52-3C₁₄H₁₉FN₂O₄S

1-Ethyl-4-[(4-fluorobenzyl)sulfonyl]piperazine chemical structure, C13H19FN2O2S, CAS 950245-91-7

1-Ethyl-4-[(4-fluorobenzyl)sulfonyl]piperazine

CAS 950245-91-7C₁₃H₁₉FN₂O₂S

1-Methyl-4-[(2-methylbenzyl)sulfonyl]piperazine chemical structure, C13H20N2O2S, CAS 950252-59-2

1-Methyl-4-[(2-methylbenzyl)sulfonyl]piperazine

CAS 950252-59-2C₁₃H₂₀N₂O₂S

1-((4-Bromobenzyl)sulfonyl)-4-methylpiperazine chemical structure, C12H17BrN2O2S, CAS 950229-48-8

1-((4-Bromobenzyl)sulfonyl)-4-methylpiperazine

CAS 950229-48-8C₁₂H₁₇BrN₂O₂S

1-[(4-Bromobenzyl)sulfonyl]-4-ethylpiperazine chemical structure, C13H19BrN2O2S, CAS 950246-22-7

1-[(4-Bromobenzyl)sulfonyl]-4-ethylpiperazine

CAS 950246-22-7C₁₃H₁₉BrN₂O₂S

Ethyl 4-((2,4-dichlorobenzyl)sulfonyl)piperazine-1-carboxylate chemical structure, C14H18Cl2N2O4S, CAS 950247-06-0

Ethyl 4-((2,4-dichlorobenzyl)sulfonyl)piperazine-1-carboxylate

CAS 950247-06-0C₁₄H₁₈Cl₂N₂O₄S

1-[(2-Chloro-6-fluorobenzyl)sulfonyl]-4-methylpiperazine chemical structure, C12H16ClFN2O2S, CAS 950239-98-2

1-[(2-Chloro-6-fluorobenzyl)sulfonyl]-4-methylpiperazine

CAS 950239-98-2C₁₂H₁₆ClFN₂O₂S

Ethyl 4-[(3-methylbenzyl)sulfonyl]piperazine-1-carboxylate chemical structure, C15H22N2O4S, CAS 950244-58-3

Ethyl 4-[(3-methylbenzyl)sulfonyl]piperazine-1-carboxylate

CAS 950244-58-3C₁₅H₂₂N₂O₄S

1-Ethyl-4-[(4-methylbenzyl)sulfonyl]piperazine chemical structure, C14H22N2O2S, CAS 950245-22-4

1-Ethyl-4-[(4-methylbenzyl)sulfonyl]piperazine

CAS 950245-22-4C₁₄H₂₂N₂O₂S

1-[(4-Chlorobenzyl)sulfonyl]-4-ethylpiperazine chemical structure, C13H19ClN2O2S, CAS 880333-73-3

1-[(4-Chlorobenzyl)sulfonyl]-4-ethylpiperazine

CAS 880333-73-3C₁₃H₁₉ClN₂O₂S

1-Methyl-4-{[4-(trifluoromethyl)phenyl]methanesulfonyl}piperazine chemical structure, C13H17F3N2O2S, CAS 936083-55-5

1-Methyl-4-{[4-(trifluoromethyl)phenyl]methanesulfonyl}piperazine

CAS 936083-55-5C₁₃H₁₇F₃N₂O₂S