Murcko scaffold
Spirohexane scaffold
393 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 6
- Chemicals
- 393
- With full pages
- 87
Scaffold SMILES
C1CC2(C1)CC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 393 chemicals
Spirohexane
CAS 157-45-9C6H10
![Spiro[2.3]hexane-1,1,2,2-tetracarbonitrile chemical structure, C10H6N4, CAS 94584-69-7](/s/JPAVHVSLQZXLDG-UHFFFAOYSA-N.svg)
Spiro[2.3]hexane-1,1,2,2-tetracarbonitrile
CAS 94584-69-7C10H6N4
![Ethyl spiro[2.3]hexane-1-carboxylate chemical structure, C9H14O2, CAS 17202-57-2](/s/NMHNCGKWEZUMIX-UHFFFAOYSA-N.svg)
Ethyl spiro[2.3]hexane-1-carboxylate
CAS 17202-57-2C9H14O2
![2-Methoxycarbonylspiro[2.3]hexane chemical structure, C8H12O2, CAS 893750-85-1](/s/LQVCYEFOCQOSDM-UHFFFAOYSA-N.svg)
2-Methoxycarbonylspiro[2.3]hexane
CAS 893750-85-1C8H12O2
![1,1-Dibromospiro[2.3]hexane chemical structure, C6H8Br2, CAS 33669-81-7](/s/RBGBBKXQFGLLBJ-UHFFFAOYSA-N.svg)
1,1-Dibromospiro[2.3]hexane
CAS 33669-81-7C6H8Br2
Spiro(2.3)hexane-1-carboxylic Acid
CAS 17202-56-1C7H10O2
![(2R)-Spiro[2.3]hexane-2-carboxylic acid chemical structure, C7H10O2, CAS 2199141-25-6](/s/VVSCGNLRDCLHAN-YFKPBYRVSA-N.svg)
(2R)-Spiro[2.3]hexane-2-carboxylic acid
CAS 2199141-25-6C7H10O2
![1-(Aminomethyl)spiro[2.3]hexane-1-carboxylic acid chemical structure, C8H13NO2, CAS 724773-02-8](/s/OVDIEYUKKNZPEH-UHFFFAOYSA-N.svg)
1-(Aminomethyl)spiro[2.3]hexane-1-carboxylic acid
CAS 724773-02-8C8H13NO2
![Diethyl Spiro[2.3]hexane-5,5-dicarboxylate chemical structure, C12H18O4, CAS 173203-62-8](/s/PSZLXAJGZJJNDR-UHFFFAOYSA-N.svg)
Diethyl Spiro[2.3]hexane-5,5-dicarboxylate
CAS 173203-62-8C12H18O4
![(2S)-Spiro[2.3]hexane-2-carboxylic acid chemical structure, C7H10O2, CAS 2382454-58-0](/s/VVSCGNLRDCLHAN-RXMQYKEDSA-N.svg)
(2S)-Spiro[2.3]hexane-2-carboxylic acid
CAS 2382454-58-0C7H10O2
![Spiro[2.3]hexane-5-carbonitrile chemical structure, C7H9N, CAS 872988-59-5](/s/ALEHCHMDJFQQAJ-UHFFFAOYSA-N.svg)
Spiro[2.3]hexane-5-carbonitrile
CAS 872988-59-5C7H9N
Spiro(2.3)hexane-5-carbonyl chloride
CAS 342614-34-0C7H9ClO
![Ethyl spiro[2.3]hexane-5-carboxylate chemical structure, C9H14O2, CAS 342616-10-8](/s/YBVHLDPLWORQSF-UHFFFAOYSA-N.svg)
Ethyl spiro[2.3]hexane-5-carboxylate
CAS 342616-10-8C9H14O2
![Spiro[2.3]hexane-4-carbohydrazide chemical structure, C7H12N2O, CAS 66036-87-1](/s/KVLYWCHAIALPQW-UHFFFAOYSA-N.svg)
Spiro[2.3]hexane-4-carbohydrazide
CAS 66036-87-1C7H12N2O
![Spiro[2.3]hexane-5-carbohydrazide chemical structure, C7H12N2O, CAS 66036-89-3](/s/PGHQSIHDNYZRRX-UHFFFAOYSA-N.svg)
Spiro[2.3]hexane-5-carbohydrazide
CAS 66036-89-3C7H12N2O
![Spiro[2.3]hexan-4-ol chemical structure, C6H10O, CAS 21816-25-1](/s/RUZFXXZSPJQNDV-UHFFFAOYSA-N.svg)
Spiro[2.3]hexan-4-ol
CAS 21816-25-1C6H10O
![Spiro[2.3]hexan-5-ol chemical structure, C6H10O, CAS 20054-19-7](/s/YVTRNUCBKIZFEO-UHFFFAOYSA-N.svg)
Spiro[2.3]hexan-5-ol
CAS 20054-19-7C6H10O
1-Bromospiro(2.3)hexane
CAS 71153-28-1C6H9Br
1-(Methoxycarbonyl)spiro(2.3)hexane-1-carboxylic acid
CAS 445306-40-1C9H12O4
![Dimethyl spiro[2.3]hexane-1,1-dicarboxylate chemical structure, C10H14O4, CAS 445306-39-8](/s/XYCBQCBNTAARQS-UHFFFAOYSA-N.svg)
Dimethyl spiro[2.3]hexane-1,1-dicarboxylate
CAS 445306-39-8C10H14O4
![Ethyl 4-aminospiro[2.3]hexane-4-carboxylate chemical structure, C9H15NO2, CAS 445306-48-9](/s/SFCRKRRKTWYOQP-UHFFFAOYSA-N.svg)
Ethyl 4-aminospiro[2.3]hexane-4-carboxylate
CAS 445306-48-9C9H15NO2
![Methyl 1-aminospiro[2.3]hexane-1-carboxylate chemical structure, C8H13NO2, CAS 761394-75-6](/s/FVOGRNQYJSGESU-UHFFFAOYSA-N.svg)
Methyl 1-aminospiro[2.3]hexane-1-carboxylate
CAS 761394-75-6C8H13NO2
![1-Aminospiro[2.3]hexane-1-carboxylic acid chemical structure, C7H11NO2, CAS 625827-37-4](/s/YENHFGZMZBROAK-UHFFFAOYSA-N.svg)
1-Aminospiro[2.3]hexane-1-carboxylic acid
CAS 625827-37-4C7H11NO2
![Spiro[2.3]hexane-1,1-dicarboxylic acid chemical structure, C8H10O4, CAS 2382956-11-6](/s/RDHXBAOEIYKMQA-UHFFFAOYSA-N.svg)
Spiro[2.3]hexane-1,1-dicarboxylic acid
CAS 2382956-11-6C8H10O4
- 5-Aminospiro[2.3]hexane-5-carboxylic acid1314939-85-9C7H11NO2
- 1-(1,2,2-Trimethylspiro[2.3]hexan-6-yl)ethanone187987-75-3C11H18O
- Spiro[2.3]hexane-1-carboxamide17202-58-3C7H11NO
- Spiro[2.3]hexan-1-amine17202-60-7C6H11N
- Spiro[2.3]hexan-4-amine38772-80-4C6H11N
- 4-Aminospiro[2.3]hexane-4-carboxylic acid1314973-90-4C7H11NO2
- N-Methylspiro[2.3]hexane-1-carboxamide1385031-06-0C8H13NO
- Spiro[2.3]hexane-5-carboxylic acid1273567-26-2C7H10O2
- Spiro[2.3]hexan-5-amine38772-81-5C6H11N
- [5-(Aminomethyl)spiro[2.3]hexan-5-yl]methanol1485249-60-2C8H15NO
- 5-Cyanospiro[2.3]hexane-5-carboxylic acid1491982-69-4C8H9NO2
- Spiro[2.3]hexan-5-ylmethanamine1495658-59-7C7H13N
- 5-(Aminomethyl)spiro[2.3]hexane-5-carboxylic acid1481181-78-5C8H13NO2
- 5-Methanesulfonylspiro[2.3]hexane-5-carboxylic acid1481200-76-3C8H12O4S
- Methyl 5-(aminomethyl)spiro[2.3]hexane-5-carboxylate1465033-86-6C9H15NO2
- Ethyl 5-(aminomethyl)spiro[2.3]hexane-5-carboxylate1498629-39-2C10H17NO2
- 5-(Propylsulfanyl)spiro[2.3]hexane-5-carboxylic acid1480831-26-2C10H16O2S
- 5-(Ethylsulfanyl)spiro[2.3]hexane-5-carboxylic acid1466800-32-7C9H14O2S
- 5-(Methylsulfanyl)spiro[2.3]hexane-5-carboxylic acid1465256-77-2C8H12O2S
- 5-(tert-Butylsulfanyl)spiro[2.3]hexane-5-carboxylic acid1491381-87-3C11H18O2S
- 5-(Propan-2-ylsulfanyl)spiro[2.3]hexane-5-carboxylic acid1484582-84-4C10H16O2S
- 5-(Butan-2-ylsulfanyl)spiro[2.3]hexane-5-carboxylic acid1469734-99-3C11H18O2S
- 5-(Isobutylthio)spiro[2.3]hexane-5-carboxylic acid1482303-91-2C11H18O2S
- Methyl 1-aminospiro[2.3]hexane-1-carboxylate hydrochloride445306-41-2C8H14ClNO2
Related scaffolds
Same ring framework with different atoms or bond orders
