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Murcko scaffold

Ring system with 2 rings and 11 atoms

48 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
48
With full pages
5
Scaffold SMILES

O=S1(=O)NCCc2ccsc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S1(=O)NCCc2ccsc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

Brinzolamide chemical structure, C12H21N3O5S3, CAS 138890-62-7
Brinzolamide
CAS 138890-62-7C12H21N3O5S3
AL-4623 chemical structure, C11H19N3O5S3, CAS 138890-59-2
AL-4623
CAS 138890-59-2C11H19N3O5S3
Brinzolamide, (S)- chemical structure, C12H21N3O5S3, CAS 154127-19-2
Brinzolamide, (S)-
CAS 154127-19-2C12H21N3O5S3
(4S)-6-Chloro-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno(3,2-e)thiazin-4-ol chemical structure, C10H14ClNO4S2, CAS 160982-13-8
(4S)-6-Chloro-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno(3,2-e)thiazin-4-ol
CAS 160982-13-8C10H14ClNO4S2
N-Desethyl brinzolamide chemical structure, C10H17N3O5S3, CAS 404034-55-5
N-Desethyl brinzolamide
CAS 404034-55-5C10H17N3O5S3
2H-Thieno(3,2-E)-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-methyl-, 1,1-dioxide, hydrochloride (1:1), (4R)- chemical structure, C9H16ClN3O4S3, CAS 138890-75-2
2H-Thieno(3,2-E)-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-methyl-, 1,1-dioxide, hydrochloride (1:1), (4R)-
CAS 138890-75-2C9H16ClN3O4S3
2H-Thieno(3,2-E)-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-methyl-, 1,1-dioxide, (4R)- chemical structure, C9H15N3O4S3, CAS 138890-58-1
2H-Thieno(3,2-E)-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-methyl-, 1,1-dioxide, (4R)-
CAS 138890-58-1C9H15N3O4S3
6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-dioxide chemical structure, C6H6ClNO3S2, CAS 171274-01-4
6-Chloro-4-hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-dioxide
CAS 171274-01-4C6H6ClNO3S2
(4S)-4-Hydroxy-2-(2-methoxyethyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide chemical structure, C9H14N2O6S3, CAS 154127-33-0
(4S)-4-Hydroxy-2-(2-methoxyethyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide
CAS 154127-33-0C9H14N2O6S3
6-Chloro-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazin-4-ol 1, 1-dioxide chemical structure, C10H14ClNO4S2, CAS 174139-71-0
6-Chloro-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazin-4-ol 1, 1-dioxide
CAS 174139-71-0C10H14ClNO4S2
Brinzolamide hydrochloride chemical structure, C12H22ClN3O5S3, CAS 150937-43-2
Brinzolamide hydrochloride
CAS 150937-43-2C12H22ClN3O5S3
(4S)-6-Chloro-1,1-dioxo-3,4-dihydro-2H-thieno(3,2-e)thiazin-4-ol chemical structure, C6H6ClNO3S2, CAS 138890-89-8
(4S)-6-Chloro-1,1-dioxo-3,4-dihydro-2H-thieno(3,2-e)thiazin-4-ol
CAS 138890-89-8C6H6ClNO3S2
4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno(3,2-E)(1,2)thiazine-6-sulfonamide 1,1-dioxide, (S)- chemical structure, C10H16N2O6S3, CAS 154127-42-1
4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno(3,2-E)(1,2)thiazine-6-sulfonamide 1,1-dioxide, (S)-
CAS 154127-42-1C10H16N2O6S3
(4S)-1,1-Dioxide-3,4-dihydro-4-hydroxy-2- chemical structure, C10H16N2O6S3, CAS 154127-40-9
(4S)-1,1-Dioxide-3,4-dihydro-4-hydroxy-2-
CAS 154127-40-9C10H16N2O6S3
(4S)-6-Chloro-4-hydroxy-2-(2-methoxyethyl)-3,4-dihydro-1lambda~6~-thieno[3,2-e][1,2]thiazine-1,1(2H)-dione chemical structure, C9H12ClNO4S2, CAS 160982-12-7
(4S)-6-Chloro-4-hydroxy-2-(2-methoxyethyl)-3,4-dihydro-1lambda~6~-thieno[3,2-e][1,2]thiazine-1,1(2H)-dione
CAS 160982-12-7C9H12ClNO4S2
2H-Thieno(3,2-E)-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(2-methoxyethyl)-, 1,1-dioxide, monohydrochloride, (R)- chemical structure, C11H20ClN3O5S3, CAS 138890-81-0
2H-Thieno(3,2-E)-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(2-methoxyethyl)-, 1,1-dioxide, monohydrochloride, (R)-
CAS 138890-81-0C11H20ClN3O5S3
4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-dioxide chemical structure, C10H15NO4S2, CAS 165116-93-8
4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-dioxide
CAS 165116-93-8C10H15NO4S2
4-Hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-dioxide chemical structure, C6H7NO3S2, CAS 138890-97-8
4-Hydroxy-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine 1,1-dioxide
CAS 138890-97-8C6H7NO3S2
2H-Thieno[3,2-e]-1,2-thiazin-4-amine, N-ethyl-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)- chemical structure, C12H20N2O3S2, CAS 1029324-92-2
2H-Thieno[3,2-e]-1,2-thiazin-4-amine, N-ethyl-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-
CAS 1029324-92-2C12H20N2O3S2
(4S)-3,4-Dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazin-4-ol 1,1-Dioxide chemical structure, C10H15NO4S2, CAS 1029324-91-1
(4S)-3,4-Dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazin-4-ol 1,1-Dioxide
CAS 1029324-91-1C10H15NO4S2
2H-Thieno[3,2-e]-1,2-thiazin-4-amine, N-ethyl-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide chemical structure, C12H20N2O3S2, CAS 1072782-84-3
2H-Thieno[3,2-e]-1,2-thiazin-4-amine, N-ethyl-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide
CAS 1072782-84-3C12H20N2O3S2
(R)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-E][1,2]thiazine-6-sulfonamide 1,1-dioxide chemical structure, C10H16N2O6S3, CAS 165117-54-4
(R)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-E][1,2]thiazine-6-sulfonamide 1,1-dioxide
CAS 165117-54-4C10H16N2O6S3
Brinzolamide-d5 chemical structure, C12H21N3O5S3, CAS 1217651-02-9
Brinzolamide-d5
CAS 1217651-02-9C12H21N3O5S3
O-Desmethyl brinzolamide chemical structure, C11H19N3O5S3, CAS 186377-56-0
O-Desmethyl brinzolamide
CAS 186377-56-0C11H19N3O5S3