Murcko scaffold
Ring system with 4 rings and 21 atoms
27 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 27
- With full pages
- 5
Scaffold SMILES
O=C1CC(c2ccccc2)Oc2cc3c(cc21)C=CCO3
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 27 of 27 chemicals
Flemichin D
CAS 57096-07-8C25H26O6
Minimiflorin
CAS 98621-33-1C25H26O5
Dorsmanin I
CAS 329703-46-0C25H26O6
Lupinifolin
CAS 55890-27-2C25H26O5
Mundulinol
CAS 71385-95-0C25H26O5
![(7R,8R)-5-Hydroxy-8-(2-hydroxyphenyl)-7-methoxy-2,2-dimethyl-10-(3-methylbut-2-enyl)-7,8-dihydropyrano[3,2-g]chromen-6-one chemical structure, C26H28O6, CAS 259812-80-1](/s/ZQNJQIORXQNFHJ-RPBOFIJWSA-N.svg)
(7R,8R)-5-Hydroxy-8-(2-hydroxyphenyl)-7-methoxy-2,2-dimethyl-10-(3-methylbut-2-enyl)-7,8-dihydropyrano[3,2-g]chromen-6-one
CAS 259812-80-1C26H28O6
(2S)-4',5-Dihydroxy-8-hydroxymethyl-6'',6''-dimethylpyrano(2'',3'':7,6)flavanone
CAS 466689-44-1C21H20O6
Buceracidin A
CAS 485831-90-1C21H20O6
5-Dehydroxyparatocarpin K
CAS 124858-37-3C20H18O4
Paratocarpin K
CAS 170900-13-7C20H18O5
Amoricin
CAS 119347-01-2C31H36O6
Amoridin
CAS 119347-05-6C30H34O6
Kuwanol C
CAS 123702-94-3C25H26O6
Paratocarpin I
CAS 170662-23-4C25H26O5
3'-Methoxylupinifolin
CAS 144049-80-9C26H28O6
Mundulin
CAS 71417-50-0C25H26O4
Macaflavanone B
CAS 1075194-61-4C30H34O6
8-C-Prenyl-6'',6''-dimethylpyrano(2'',3'':7,6)flavanone
CAS 102673-83-6C25H26O3
Dereticulatin
CAS 193551-72-3C25H26O6
Exiguaflavanone H
CAS 156281-18-4C30H34O7
Khonklonginol H
CAS 1159909-79-1C26H28O6
Khonklonginol A
CAS 1159909-57-5C26H28O6
Khonklonginol B
CAS 1159909-60-0C26H28O6
Fuscaflavanone A1
CAS 1198083-60-1C25H26O6
- Buceracidin B485831-91-2C20H18O5
- 8-[2,4-Dihydroxy-5-(1-hydroxy-3-methyl-2-butenyl)phenyl]-7,8-dihydro-5-hydroxy-2,2-dimethyl-10-(3-methyl-2-butenyl)-2H,6H-benzo[1,2-B:5,4-B']dipyran-6-one57096-06-7C30H34O7
- (8S)-8-(2,4-Dihydroxyphenyl)-5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-7,8-dihydropyrano[3,2-g]chromen-6-oneC25H26O6
Related scaffolds
Same ring framework with different atoms or bond orders
O=c1c(-c2ccccc2)coc2cc3c(cc12)C=CCO312 chemicals
O=C1c2ccccc2C(=O)c2cc(-c3ccccc3)ccc2110 chemicals
O=c1c2ccccc2oc2ncn(-c3ccccc3)c(=O)c126 chemicals
O=c1cc(-c2ccccc2)oc2cc3c(cc12)C=CCO35 chemicals![Scaffold O=c1[nH]c(-c2ccccc2)nc2oc3ccccc3c(=O)c12](/scaffold/CGPLJIKMEYWEPS-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(-c2ccccc2)nc2oc3ccccc3c(=O)c125 chemicals
O=C1c2ccccc2C(=O)c2cc(C3CCCCO3)ccc215 chemicals
O=c1c2ccccc2oc2ccc(C3CCCCO3)cc124 chemicals![Scaffold O=c1[nH]c(-c2ccccc2)nc2[nH]c3ccccc3c(=O)c12](/scaffold/CCPOXISGMVQAOA-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(-c2ccccc2)nc2[nH]c3ccccc3c(=O)c123 chemicals
O=c1oc2cc3c(cc2cc1-c1ccccc1)C=CCO33 chemicals![Scaffold O=c1c2cc3c(nc2[nH]c(=S)n1-c1ccccc1)CCOC3](/scaffold/UVDVBAXATWJUAF-UHFFFAOYSA-N/structure.svg)
O=c1c2cc3c(nc2[nH]c(=S)n1-c1ccccc1)CCOC33 chemicals
c1ccc2c(c1)Nc1cc(N3CCNCC3)nnc1O22 chemicals
O=C1c2cc3c(cc2OCC1c1ccccc1)OCC=C32 chemicals