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Murcko scaffold

Ring system with 4 rings and 22 atoms

26 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 26
With full pages: 5

Scaffold SMILES

O=c1[nH]c(-c2ccccc2)nc2oc3ccccc3c(=O)c12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1[nH]c(-c2ccccc2)nc2oc3ccccc3c(=O)c12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

3-(2-Methoxyethyl)-2-(3,4,5-trimethoxyphenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C23H22N2O7, CAS 896075-95-9

3-(2-Methoxyethyl)-2-(3,4,5-trimethoxyphenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896075-95-9C₂₃H₂₂N₂O₇

2-(4-Chlorophenyl)-8-methoxy-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C21H17ClN2O5, CAS 896593-84-3

2-(4-Chlorophenyl)-8-methoxy-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896593-84-3C₂₁H₁₇ClN₂O₅

2-(4-Bromophenyl)-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C20H15BrN2O4, CAS 896594-39-1

2-(4-Bromophenyl)-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896594-39-1C₂₀H₁₅BrN₂O₄

2-(4-Fluorophenyl)-8-methoxy-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C22H19FN2O5, CAS 896812-49-0

2-(4-Fluorophenyl)-8-methoxy-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896812-49-0C₂₂H₁₉FN₂O₅

8-Methoxy-3-(3-methoxypropyl)-2-(3,4,5-trimethoxyphenyl)chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C25H26N2O8, CAS 883953-62-6

8-Methoxy-3-(3-methoxypropyl)-2-(3,4,5-trimethoxyphenyl)chromeno[2,3-d]pyrimidine-4,5-dione

CAS 883953-62-6C₂₅H₂₆N₂O₈

8-Methoxy-3-(2-methoxyethyl)-2-(4-methoxyphenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C22H20N2O6, CAS 883953-45-5

8-Methoxy-3-(2-methoxyethyl)-2-(4-methoxyphenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 883953-45-5C₂₂H₂₀N₂O₆

2-(4-Methoxyphenyl)-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C22H20N2O5, CAS 896813-74-4

2-(4-Methoxyphenyl)-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896813-74-4C₂₂H₂₀N₂O₅

2-(3-Bromophenyl)-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C20H15BrN2O4, CAS 896818-96-5

2-(3-Bromophenyl)-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896818-96-5C₂₀H₁₅BrN₂O₄

2-(2,4-Dichlorophenyl)-8-methoxy-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C21H16Cl2N2O5, CAS 896835-51-1

2-(2,4-Dichlorophenyl)-8-methoxy-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896835-51-1C₂₁H₁₆Cl₂N₂O₅

2-(2-Fluorophenyl)-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C21H17FN2O4, CAS 896842-39-0

2-(2-Fluorophenyl)-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896842-39-0C₂₁H₁₇FN₂O₄

2-(4-Bromophenyl)-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C21H17BrN2O4, CAS 896844-74-9

2-(4-Bromophenyl)-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896844-74-9C₂₁H₁₇BrN₂O₄

3-Butyl-7-chloro-2-(3-nitrophenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C21H16ClN3O5, CAS 879443-31-9

3-Butyl-7-chloro-2-(3-nitrophenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 879443-31-9C₂₁H₁₆ClN₃O₅

2-(4-Fluorophenyl)-8-methoxy-3-(2-methoxyethyl)chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C21H17FN2O5, CAS 896852-34-9

2-(4-Fluorophenyl)-8-methoxy-3-(2-methoxyethyl)chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896852-34-9C₂₁H₁₇FN₂O₅

3-Butyl-2-(2-chlorophenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C21H17ClN2O3, CAS 883956-48-7

3-Butyl-2-(2-chlorophenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 883956-48-7C₂₁H₁₇ClN₂O₃

2-(4-Chlorophenyl)-8-methoxy-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C22H19ClN2O5, CAS 896857-58-2

2-(4-Chlorophenyl)-8-methoxy-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896857-58-2C₂₂H₁₉ClN₂O₅

8-Methoxy-3-(2-methoxyethyl)-2-(p-tolyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C22H20N2O5, CAS 899396-41-9

8-Methoxy-3-(2-methoxyethyl)-2-(p-tolyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 899396-41-9C₂₂H₂₀N₂O₅

3-Butyl-2-(p-tolyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C22H20N2O3, CAS 883956-07-8

3-Butyl-2-(p-tolyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 883956-07-8C₂₂H₂₀N₂O₃

2-(4-(tert-Butyl)phenyl)-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C25H26N2O4, CAS 899400-05-6

2-(4-(tert-Butyl)phenyl)-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 899400-05-6C₂₅H₂₆N₂O₄

3-Butyl-2-(4-chlorophenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C21H17ClN2O3, CAS 883956-12-5

3-Butyl-2-(4-chlorophenyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 883956-12-5C₂₁H₁₇ClN₂O₃

2-(2,4-Dichlorophenyl)-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C20H14Cl2N2O4, CAS 883953-51-3

2-(2,4-Dichlorophenyl)-3-(2-methoxyethyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 883953-51-3C₂₀H₁₄Cl₂N₂O₄

3-Butyl-2-(o-tolyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C22H20N2O3, CAS 899385-52-5

3-Butyl-2-(o-tolyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 899385-52-5C₂₂H₂₀N₂O₃

2-(4-(tert-Butyl)phenyl)-8-methoxy-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C26H28N2O5, CAS 896074-82-1

2-(4-(tert-Butyl)phenyl)-8-methoxy-3-(3-methoxypropyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 896074-82-1C₂₆H₂₈N₂O₅

3-Butyl-8-methoxy-2-phenyl-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C22H20N2O4, CAS 883955-94-0

3-Butyl-8-methoxy-2-phenyl-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 883955-94-0C₂₂H₂₀N₂O₄

3-(3-Methoxypropyl)-2-(p-tolyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione chemical structure, C22H20N2O4, CAS 883952-29-2

3-(3-Methoxypropyl)-2-(p-tolyl)-3H-chromeno[2,3-d]pyrimidine-4,5-dione

CAS 883952-29-2C₂₂H₂₀N₂O₄