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Murcko scaffold

5-[[4-[2-(2-Pyridinylamino)ethoxy]phenyl]methylene]-2,4-thiazolidinedione scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
7
With full pages
2
Scaffold SMILES

O=C1NC(=O)C(=Cc2ccc(OCCNc3ccccn3)cc2)S1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-[[4-[2-(2-Pyridinylamino)ethoxy]phenyl]methylene]-2,4-thiazolidinedione page
Murcko scaffold O=C1NC(=O)C(=Cc2ccc(OCCNc3ccccn3)cc2)S1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Didehydro rosiglitazone, (5Z)- chemical structure, C18H17N3O3S, CAS 160596-25-8
Didehydro rosiglitazone, (5Z)-
CAS 160596-25-8C18H17N3O3S
2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methylene]-, (5E)-, 2,2,2-trifluoroacetate (1:1) chemical structure, C20H18F3N3O5S, CAS 1184038-74-1
2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methylene]-, (5E)-, 2,2,2-trifluoroacetate (1:1)
CAS 1184038-74-1C20H18F3N3O5S
5-[4-[N-(2-Pyridylamino)ethoxy]benzylidene]thiazolidine-2,4-dione chemical structure, C17H15N3O3S
5-[4-[N-(2-Pyridylamino)ethoxy]benzylidene]thiazolidine-2,4-dione
C17H15N3O3S
5-[4-[2-((Methyl-d3)pyridin-2-ylamino)ethoxy]benzylidene]thiazolidine-2,4-dione chemical structure, C18H17N3O3S, CAS 1185245-57-1
5-[4-[2-((Methyl-d3)pyridin-2-ylamino)ethoxy]benzylidene]thiazolidine-2,4-dione
CAS 1185245-57-1C18H17N3O3S
5-[4-[2-[N-(Methyl)-N-(2-pyridyl)amino]ethoxy]benzylidene]thiazolidine-2,4-dione chemical structure, C18H17N3O3S, CAS 122320-74-5
5-[4-[2-[N-(Methyl)-N-(2-pyridyl)amino]ethoxy]benzylidene]thiazolidine-2,4-dione
CAS 122320-74-5C18H17N3O3S
5-[[4-[2-(2-Pyridinylamino)ethoxy]phenyl]methylene]-2,4-thiazolidinedione chemical structure, C17H15N3O3S, CAS 643764-88-9
5-[[4-[2-(2-Pyridinylamino)ethoxy]phenyl]methylene]-2,4-thiazolidinedione
CAS 643764-88-9C17H15N3O3S
(5E)-5-[[4-[2-(Pyridin-2-ylamino)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione chemical structure, C17H15N3O3S
(5E)-5-[[4-[2-(Pyridin-2-ylamino)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione
C17H15N3O3S