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Murcko scaffold

Ring system with 3 rings and 20 atoms

48 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
48
With full pages
5
Scaffold SMILES

O=C(Nc1cnn(Cc2ccccc2)c1)c1cc[nH]n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cnn(Cc2ccccc2)c1)c1cc[nH]n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

N-[1-[(3-Fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-4-iodo-2-methylpyrazole-3-carboxamide chemical structure, C17H17FIN5O, CAS 512812-26-9
N-[1-[(3-Fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-4-iodo-2-methylpyrazole-3-carboxamide
CAS 512812-26-9C17H17FIN5O
N-[1-(3-Fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-4-iodo-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C17H17FIN5O, CAS 512814-25-4
N-[1-(3-Fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-4-iodo-1-methyl-1H-pyrazole-3-carboxamide
CAS 512814-25-4C17H17FIN5O
4-Chloro-N-[1-(3-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-5-carboxamide chemical structure, C17H17ClFN5O, CAS 512826-31-2
4-Chloro-N-[1-(3-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-5-carboxamide
CAS 512826-31-2C17H17ClFN5O
4-Chloro-N-[3,5-dimethyl-1-(2-methylbenzyl)-1H-pyrazol-4-yl]-1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxamide chemical structure, C19H19ClF3N5O, CAS 512823-90-4
4-Chloro-N-[3,5-dimethyl-1-(2-methylbenzyl)-1H-pyrazol-4-yl]-1-methyl-5-(trifluoromethyl)-1H-pyrazole-3-carboxamide
CAS 512823-90-4C19H19ClF3N5O
N-[1-[(3-Fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2,5-dimethyl-4-nitropyrazole-3-carboxamide chemical structure, C18H19FN6O3, CAS 512823-30-2
N-[1-[(3-Fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2,5-dimethyl-4-nitropyrazole-3-carboxamide
CAS 512823-30-2C18H19FN6O3
4-Chloro-1-ethyl-N-[1-(3-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1H-pyrazole-3-carboxamide chemical structure, C18H19ClFN5O, CAS 512817-97-9
4-Chloro-1-ethyl-N-[1-(3-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1H-pyrazole-3-carboxamide
CAS 512817-97-9C18H19ClFN5O
N-[1-(3-Fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-4-iodo-1H-pyrazole-3-carboxamide chemical structure, C16H15FIN5O, CAS 512816-23-8
N-[1-(3-Fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-4-iodo-1H-pyrazole-3-carboxamide
CAS 512816-23-8C16H15FIN5O
4-Chloro-N-[1-(2,4-dichlorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C15H12Cl3N5O, CAS 514800-89-6
4-Chloro-N-[1-(2,4-dichlorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide
CAS 514800-89-6C15H12Cl3N5O
4-Chloro-N-[3,5-dimethyl-1-(4-methylbenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C18H20ClN5O, CAS 489450-87-5
4-Chloro-N-[3,5-dimethyl-1-(4-methylbenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide
CAS 489450-87-5C18H20ClN5O
4-Chloro-N-[1-(4-chlorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C17H17Cl2N5O, CAS 489450-89-7
4-Chloro-N-[1-(4-chlorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide
CAS 489450-89-7C17H17Cl2N5O
4-Chloro-N-[1-(4-fluorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C15H13ClFN5O, CAS 489450-91-1
4-Chloro-N-[1-(4-fluorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide
CAS 489450-91-1C15H13ClFN5O
4-Chloro-N-[1-(4-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C17H17ClFN5O, CAS 489451-00-5
4-Chloro-N-[1-(4-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide
CAS 489451-00-5C17H17ClFN5O
N-[1-(2-Chloro-6-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C17H17ClFN5O, CAS 515849-15-7
N-[1-(2-Chloro-6-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide
CAS 515849-15-7C17H17ClFN5O
N-[1-(3,4-Dichlorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C15H13Cl2N5O, CAS 515850-00-7
N-[1-(3,4-Dichlorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide
CAS 515850-00-7C15H13Cl2N5O
1-Ethyl-N-[1-(3-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1H-pyrazole-5-carboxamide chemical structure, C18H20FN5O, CAS 1005689-34-8
1-Ethyl-N-[1-(3-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1H-pyrazole-5-carboxamide
CAS 1005689-34-8C18H20FN5O
4-Bromo-N-[3,5-dimethyl-1-(2,3,4,5,6-pentafluorobenzyl)-1H-pyrazol-4-yl]-1,3-dimethyl-1H-pyrazole-5-carboxamide chemical structure, C18H15BrF5N5O, CAS 512816-78-3
4-Bromo-N-[3,5-dimethyl-1-(2,3,4,5,6-pentafluorobenzyl)-1H-pyrazol-4-yl]-1,3-dimethyl-1H-pyrazole-5-carboxamide
CAS 512816-78-3C18H15BrF5N5O
4-Chloro-1-methyl-N-[1-(2-methylbenzyl)-1H-pyrazol-4-yl]-1H-pyrazole-3-carboxamide chemical structure, C16H16ClN5O, CAS 489450-34-2
4-Chloro-1-methyl-N-[1-(2-methylbenzyl)-1H-pyrazol-4-yl]-1H-pyrazole-3-carboxamide
CAS 489450-34-2C16H16ClN5O
N-[1-(4-Chlorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-5-carboxamide chemical structure, C17H18ClN5O, CAS 494216-82-9
N-[1-(4-Chlorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-5-carboxamide
CAS 494216-82-9C17H18ClN5O
N-[1-(2,6-Dichlorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide chemical structure, C17H17Cl2N5O, CAS 515850-18-7
N-[1-(2,6-Dichlorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-3-carboxamide
CAS 515850-18-7C17H17Cl2N5O
N-[1-[(4-Chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-1-methylpyrazole-3-carboxamide chemical structure, C17H18ClN5O, CAS 488822-00-0
N-[1-[(4-Chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-1-methylpyrazole-3-carboxamide
CAS 488822-00-0C17H18ClN5O
4-Chloro-N-[3,5-dimethyl-1-(2,3,4,5,6-pentafluorobenzyl)-1H-pyrazol-4-yl]-1-ethyl-1H-pyrazole-3-carboxamide chemical structure, C18H15ClF5N5O, CAS 512817-62-8
4-Chloro-N-[3,5-dimethyl-1-(2,3,4,5,6-pentafluorobenzyl)-1H-pyrazol-4-yl]-1-ethyl-1H-pyrazole-3-carboxamide
CAS 512817-62-8C18H15ClF5N5O
N-[1-(4-Fluorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-5-carboxamide chemical structure, C15H14FN5O, CAS 515849-43-1
N-[1-(4-Fluorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-5-carboxamide
CAS 515849-43-1C15H14FN5O
N-[1-[(4-Fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2-methylpyrazole-3-carboxamide chemical structure, C17H18FN5O, CAS 515831-47-7
N-[1-[(4-Fluorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-2-methylpyrazole-3-carboxamide
CAS 515831-47-7C17H18FN5O
N-[1-(3,4-Dichlorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-5-carboxamide chemical structure, C15H13Cl2N5O, CAS 515848-81-4
N-[1-(3,4-Dichlorobenzyl)-1H-pyrazol-4-yl]-1-methyl-1H-pyrazole-5-carboxamide
CAS 515848-81-4C15H13Cl2N5O