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Murcko scaffold

Ring system with 4 rings and 22 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
8
With full pages
3
Scaffold SMILES

C=C1C=COC(C=Cc2cc3c4c(c2)CCCN4CCC3)=C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1C=COC(C=Cc2cc3c4c(c2)CCCN4CCC3)=C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-[2-[(E)-2-(1-Azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-trien-7-yl)ethenyl]-6-methylpyran-4-ylidene]propanedinitrile chemical structure, C23H21N3O, CAS 866626-85-9
2-[2-[(E)-2-(1-Azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-trien-7-yl)ethenyl]-6-methylpyran-4-ylidene]propanedinitrile
CAS 866626-85-9C23H21N3O
4-(Dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidin-4-yl-vinyl)-4H-pyran chemical structure, C30H35N3O, CAS 200052-70-6
4-(Dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidin-4-yl-vinyl)-4H-pyran
CAS 200052-70-6C30H35N3O
4-(Dicyanomethylene)-2-methyl-6-(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H-pyran chemical structure, C27H29N3O, CAS 159788-00-8
4-(Dicyanomethylene)-2-methyl-6-(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H-pyran
CAS 159788-00-8C27H29N3O
2-(2-Isopropyl-6-(2-(1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido(3,2,1-ij)quinolin-9-yl)-vinyl)-pyran-4-ylidene)-malononitrile chemical structure, C29H33N3O, CAS 870075-87-9
2-(2-Isopropyl-6-(2-(1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido(3,2,1-ij)quinolin-9-yl)-vinyl)-pyran-4-ylidene)-malononitrile
CAS 870075-87-9C29H33N3O
4-(Dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyl-julolidin-4-yl-vinyl)-4H-pyran chemical structure, C30H35N3O
4-(Dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyl-julolidin-4-yl-vinyl)-4H-pyran
C30H35N3O
2-(2-Methyl-6-(2-(2,3,6,7-tetrahydro-1H,5H-benzo(ij)quinolizin-9-yl)ethenyl)-4H-pyran-4-ylidene)propanedinitrile chemical structure, C23H21N3O, CAS 51325-95-2
2-(2-Methyl-6-(2-(2,3,6,7-tetrahydro-1H,5H-benzo(ij)quinolizin-9-yl)ethenyl)-4H-pyran-4-ylidene)propanedinitrile
CAS 51325-95-2C23H21N3O
7-[(E)-2-(6-tert-Butyl-4-propan-2-ylidenepyran-2-yl)ethenyl]-3,3,10,10-tetramethyl-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene chemical structure, C30H41NO, CAS 434938-12-2
7-[(E)-2-(6-tert-Butyl-4-propan-2-ylidenepyran-2-yl)ethenyl]-3,3,10,10-tetramethyl-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene
CAS 434938-12-2C30H41NO
7-[2-(6-tert-Butyl-4-propan-2-ylidenepyran-2-yl)ethenyl]-3,3,10,10-tetramethyl-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene chemical structure, C30H41NO
7-[2-(6-tert-Butyl-4-propan-2-ylidenepyran-2-yl)ethenyl]-3,3,10,10-tetramethyl-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene
C30H41NO