Murcko scaffold
Ring system with 3 rings and 22 atoms
5 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 22
- Chemicals
- 5
- With full pages
- 2
Scaffold SMILES
O=C(NCC1=NC(C(=O)N2CC=CC2=O)CS1)c1cscn1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 5 of 5 chemicals
4-Thiazolecarboxamide, N-(1-(4-((2,5-dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl)-4,5-dihydro-2-thiazolyl)-2-hydroxyethyl)-2-((hydroxyimino)methyl)-
C16H17N5O6S2
Althiomycin
C16H17N5O6S2
Orb1702576
CAS 12656-40-5C16H17N5O6S2
![2-[(Z)-Hydroxyiminomethyl]-N-[(1S)-2-hydroxy-1-[(4S)-4-(3-methoxy-5-oxo-2H-pyrrole-1-carbonyl)-4,5-dihydro-1,3-thiazol-2-yl]ethyl]-1,3-thiazole-4-carboxamide chemical structure, C16H17N5O6S2](/s/VQQNQKXWJMRPHT-GBXZPXMESA-N.svg)
2-[(Z)-Hydroxyiminomethyl]-N-[(1S)-2-hydroxy-1-[(4S)-4-(3-methoxy-5-oxo-2H-pyrrole-1-carbonyl)-4,5-dihydro-1,3-thiazol-2-yl]ethyl]-1,3-thiazole-4-carboxamide
C16H17N5O6S2
![2-[(E)-Hydroxyiminomethyl]-N-[(1S)-2-hydroxy-1-[(4S)-4-(3-methoxy-5-oxo-2H-pyrrole-1-carbonyl)-4,5-dihydro-1,3-thiazol-2-yl]ethyl]-1,3-thiazole-4-carboxamide chemical structure, C16H17N5O6S2](/s/VQQNQKXWJMRPHT-YNYXEJBLSA-N.svg)
2-[(E)-Hydroxyiminomethyl]-N-[(1S)-2-hydroxy-1-[(4S)-4-(3-methoxy-5-oxo-2H-pyrrole-1-carbonyl)-4,5-dihydro-1,3-thiazol-2-yl]ethyl]-1,3-thiazole-4-carboxamide
C16H17N5O6S2
Related scaffolds
Same ring framework with different atoms or bond orders
