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Murcko scaffold

Ring system with 2 rings and 17 atoms

4 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
4
With full pages
3
Scaffold SMILES

O=C1NCC=C(COC(=O)c2cccnc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NCC=C(COC(=O)c2cccnc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Ethyl 4-methyl-6-{[2-(methylsulfanyl)pyridine-3-carbonyloxy]methyl}-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C16H19N3O5S, CAS 791085-12-6
Ethyl 4-methyl-6-{[2-(methylsulfanyl)pyridine-3-carbonyloxy]methyl}-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 791085-12-6C16H19N3O5S
Ethyl 6-{[2-(methylsulfanyl)pyridine-3-carbonyloxy]methyl}-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C15H17N3O5S, CAS 949272-08-6
Ethyl 6-{[2-(methylsulfanyl)pyridine-3-carbonyloxy]methyl}-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 949272-08-6C15H17N3O5S
Ethyl 6-[(2-chloropyridine-3-carbonyloxy)methyl]-4-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C15H16ClN3O5, CAS 876684-43-4
Ethyl 6-[(2-chloropyridine-3-carbonyloxy)methyl]-4-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 876684-43-4C15H16ClN3O5
Ethyl 6-[(6-chloropyridine-3-carbonyloxy)methyl]-4-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C15H16ClN3O5, CAS 1090924-66-5
Ethyl 6-[(6-chloropyridine-3-carbonyloxy)methyl]-4-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 1090924-66-5C15H16ClN3O5