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Murcko scaffold

Ring system with 4 rings and 24 atoms

54 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
54
With full pages
3
Scaffold SMILES

O=C(NC1CCCNC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCCNC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 54 chemicals

9H-Fluoren-9-ylmethyl N-[(3R)-piperidin-3-yl]carbamate chemical structure, C20H22N2O2, CAS 1263046-53-2
9H-Fluoren-9-ylmethyl N-[(3R)-piperidin-3-yl]carbamate
CAS 1263046-53-2C20H22N2O2
1-((tert-Butoxy)carbonyl)-3-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)piperidine-3-carboxylic acid chemical structure, C26H30N2O6, CAS 368866-21-1
1-((tert-Butoxy)carbonyl)-3-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)piperidine-3-carboxylic acid
CAS 368866-21-1C26H30N2O6
(9H-Fluoren-9-yl)methyl piperidin-3-ylcarbamate--hydrogen chloride (1/1) chemical structure, C20H23ClN2O2, CAS 672310-13-3
(9H-Fluoren-9-yl)methyl piperidin-3-ylcarbamate--hydrogen chloride (1/1)
CAS 672310-13-3C20H23ClN2O2
(3R)-1-tert-Butoxycarbonyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)piperidine-3-carboxylic acid chemical structure, C26H30N2O6, CAS 862372-85-8
(3R)-1-tert-Butoxycarbonyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)piperidine-3-carboxylic acid
CAS 862372-85-8C26H30N2O6
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid chemical structure, C26H30N2O6, CAS 862372-91-6
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid
CAS 862372-91-6C26H30N2O6
tert-Butyl 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-aminopiperidine-1-carboxylate chemical structure, C25H31N3O4, CAS 1822457-27-1
tert-Butyl 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-aminopiperidine-1-carboxylate
CAS 1822457-27-1C25H31N3O4
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-piperidine-3-carboxylic acid hydrochloride chemical structure, C21H23ClN2O4, CAS 1134603-34-1
3-(9H-Fluoren-9-ylmethoxycarbonylamino)-piperidine-3-carboxylic acid hydrochloride
CAS 1134603-34-1C21H23ClN2O4
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)piperidine-3-carboxylic acid chemical structure, C21H22N2O4, CAS 368866-20-0
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)piperidine-3-carboxylic acid
CAS 368866-20-0C21H22N2O4
(R)-3-(Fmoc-amino)piperidine HCl chemical structure, C20H23ClN2O2, CAS 1272755-51-7
(R)-3-(Fmoc-amino)piperidine HCl
CAS 1272755-51-7C20H23ClN2O2
(9H-Fluoren-9-yl)methyl N-[1-(2-hydroxyethyl)piperidin-3-yl]carbamate chemical structure, C22H26N2O3, CAS 1856884-50-8
(9H-Fluoren-9-yl)methyl N-[1-(2-hydroxyethyl)piperidin-3-yl]carbamate
CAS 1856884-50-8C22H26N2O3
2-({1-[(tert-Butoxy)carbonyl]piperidin-3-yl}({[(9H-fluoren-9-yl)methoxy]carbonyl})amino)acetic acid chemical structure, C27H32N2O6, CAS 2138514-92-6
2-({1-[(tert-Butoxy)carbonyl]piperidin-3-yl}({[(9H-fluoren-9-yl)methoxy]carbonyl})amino)acetic acid
CAS 2138514-92-6C27H32N2O6
5-(9H-Fluoren-9-ylmethoxycarbonylamino)-1-methylpiperidine-2-carboxylic acid, hydrochloride chemical structure, C22H25ClN2O4, CAS 2416235-49-7
5-(9H-Fluoren-9-ylmethoxycarbonylamino)-1-methylpiperidine-2-carboxylic acid, hydrochloride
CAS 2416235-49-7C22H25ClN2O4
5-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-1-methylpiperidine-2-carboxylic acid chemical structure, C22H24N2O4, CAS 2416235-08-8
5-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-1-methylpiperidine-2-carboxylic acid
CAS 2416235-08-8C22H24N2O4
2-{1-[(tert-Butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)piperidin-3-yl}acetic acid chemical structure, C27H32N2O6, CAS 368866-22-2
2-{1-[(tert-Butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)piperidin-3-yl}acetic acid
CAS 368866-22-2C27H32N2O6
1-tert-Butyl 3-chloromethyl 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)piperidine-1,3-dicarboxylate chemical structure, C27H31ClN2O6, CAS 2137442-43-2
1-tert-Butyl 3-chloromethyl 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)piperidine-1,3-dicarboxylate
CAS 2137442-43-2C27H31ClN2O6
1-[(tert-Butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}(3,3,3-trifluoropropyl)amino)piperidine-3-carboxylic acid chemical structure, C29H33F3N2O6, CAS 2137458-18-3
1-[(tert-Butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}(3,3,3-trifluoropropyl)amino)piperidine-3-carboxylic acid
CAS 2137458-18-3C29H33F3N2O6
1-[(tert-Butoxy)carbonyl]-3-[ethyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]piperidine-3-carboxylic acid chemical structure, C28H34N2O6, CAS 2137447-50-6
1-[(tert-Butoxy)carbonyl]-3-[ethyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]piperidine-3-carboxylic acid
CAS 2137447-50-6C28H34N2O6
1-[(tert-Butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)piperidine-3-carboxylic acid chemical structure, C27H32N2O6, CAS 2137513-60-9
1-[(tert-Butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)piperidine-3-carboxylic acid
CAS 2137513-60-9C27H32N2O6
4-({1-[(tert-Butoxy)carbonyl]-6-methylpiperidin-3-yl}({[(9H-fluoren-9-yl)methoxy]carbonyl})amino)butanoic acid chemical structure, C30H38N2O6, CAS 2138043-43-1
4-({1-[(tert-Butoxy)carbonyl]-6-methylpiperidin-3-yl}({[(9H-fluoren-9-yl)methoxy]carbonyl})amino)butanoic acid
CAS 2138043-43-1C30H38N2O6
4-({1-[(tert-Butoxy)carbonyl]-5-methylpiperidin-3-yl}({[(9H-fluoren-9-yl)methoxy]carbonyl})amino)butanoic acid chemical structure, C30H38N2O6, CAS 2138117-82-3
4-({1-[(tert-Butoxy)carbonyl]-5-methylpiperidin-3-yl}({[(9H-fluoren-9-yl)methoxy]carbonyl})amino)butanoic acid
CAS 2138117-82-3C30H38N2O6
4-({1-[(tert-Butoxy)carbonyl]-2-methylpiperidin-3-yl}({[(9H-fluoren-9-yl)methoxy]carbonyl})amino)butanoic acid chemical structure, C30H38N2O6, CAS 2138537-49-0
4-({1-[(tert-Butoxy)carbonyl]-2-methylpiperidin-3-yl}({[(9H-fluoren-9-yl)methoxy]carbonyl})amino)butanoic acid
CAS 2138537-49-0C30H38N2O6
2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpiperidin-3-yl]acetic acid chemical structure, C23H26N2O4, CAS 2148620-61-3
2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpiperidin-3-yl]acetic acid
CAS 2148620-61-3C23H26N2O4
2-{1-[(tert-Butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpiperidin-3-yl}acetic acid chemical structure, C28H34N2O6, CAS 2148523-04-8
2-{1-[(tert-Butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpiperidin-3-yl}acetic acid
CAS 2148523-04-8C28H34N2O6
Methyl 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-hydroxy-1-methylpiperidine-4-carboxylate chemical structure, C23H26N2O5, CAS 2137506-10-4
Methyl 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-hydroxy-1-methylpiperidine-4-carboxylate
CAS 2137506-10-4C23H26N2O5