Murcko scaffold
Ring system with 5 rings and 20 atoms
8 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 20
- Chemicals
- 8
- With full pages
- 2
Scaffold SMILES
C1=CC23c4cc5c(cc4COC2CNC3CC1)OCO5
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
Pretazettine
CAS 17322-84-8C18H21NO5
Pretazettine hydrochloride
CAS 17322-85-9C18H22ClNO5
Crivelline
CAS 545-16-4C18H21NO5
Tazettine
CAS 507-79-9C18H21NO5
Tazettine hydrochloride
CAS 6024-65-3C18H22ClNO5
![rel-(3R,4aR,6aR,8S,13bR)-3,4,4a,5,6,6a-Hexahydro-3-methoxy-5-methyl-8H-[1,3]dioxolo[6,7][2]benzopyrano[3,4-c]indol-8-ol chemical structure, C18H21NO5, CAS 86064-46-2](/s/KLJOYDMUWKSYBP-PRNPZUBZSA-N.svg)
rel-(3R,4aR,6aR,8S,13bR)-3,4,4a,5,6,6a-Hexahydro-3-methoxy-5-methyl-8H-[1,3]dioxolo[6,7][2]benzopyrano[3,4-c]indol-8-ol
CAS 86064-46-2C18H21NO5
Tazettine methiodide
CAS 6798-23-8C19H24INO5
(-)-Tazettine
CAS 2286399-01-5C18H21NO5
Related scaffolds
Same ring framework with different atoms or bond orders
