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Murcko scaffold

Thiazolo[4,5-b]pyrazine scaffold

39 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
39
With full pages
4
Scaffold SMILES

c1cnc2scnc2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Thiazolo[4,5-b]pyrazine page
Murcko scaffold c1cnc2scnc2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

5,6-Dichloro-2-(trifluoromethyl)[1,3]thiazolo[4,5-b]pyrazine chemical structure, C6Cl2F3N3S, CAS 66490-65-1
5,6-Dichloro-2-(trifluoromethyl)[1,3]thiazolo[4,5-b]pyrazine
CAS 66490-65-1C6Cl2F3N3S
Thiazolo[4,5-b]pyrazine, 2-(1,1-dimethylethyl)- chemical structure, C9H11N3S, CAS 502169-80-4
Thiazolo[4,5-b]pyrazine, 2-(1,1-dimethylethyl)-
CAS 502169-80-4C9H11N3S
2-(Methylthio)thiazolo[4,5-b]pyrazine chemical structure, C6H5N3S2, CAS 87444-23-3
2-(Methylthio)thiazolo[4,5-b]pyrazine
CAS 87444-23-3C6H5N3S2
Ethyl thiazolo[4,5-b]pyrazin-2-ylcarbamate chemical structure, C8H8N4O2S, CAS 112342-69-5
Ethyl thiazolo[4,5-b]pyrazin-2-ylcarbamate
CAS 112342-69-5C8H8N4O2S
Ethyl (6-bromothiazolo[4,5-b]pyrazin-2-yl)carbamate chemical structure, C8H7BrN4O2S, CAS 112342-70-8
Ethyl (6-bromothiazolo[4,5-b]pyrazin-2-yl)carbamate
CAS 112342-70-8C8H7BrN4O2S
[1,3]Thiazolo[4,5-b]pyrazin-2-amine chemical structure, C5H4N4S, CAS 112342-71-9
[1,3]Thiazolo[4,5-b]pyrazin-2-amine
CAS 112342-71-9C5H4N4S
2-Amino-6-bromothiazolo[4,5-B]pyrazine chemical structure, C5H3BrN4S, CAS 112342-72-0
2-Amino-6-bromothiazolo[4,5-B]pyrazine
CAS 112342-72-0C5H3BrN4S
6-Bromo-2-methylthiazolo[4,5-b]pyrazine chemical structure, C6H4BrN3S, CAS 87444-41-5
6-Bromo-2-methylthiazolo[4,5-b]pyrazine
CAS 87444-41-5C6H4BrN3S
5,6-Dichloro-2-methyl[1,3]thiazolo[4,5-b]pyrazine chemical structure, C6H3Cl2N3S, CAS 66490-64-0
5,6-Dichloro-2-methyl[1,3]thiazolo[4,5-b]pyrazine
CAS 66490-64-0C6H3Cl2N3S
5,6-Dichlorothiazolo(4,5-b)pyrazine chemical structure, C5HCl2N3S, CAS 66490-66-2
5,6-Dichlorothiazolo(4,5-b)pyrazine
CAS 66490-66-2C5HCl2N3S
Thiazolo[4,5-b]pyrazine chemical structure, C5H3N3S, CAS 274-00-0
Thiazolo[4,5-b]pyrazine
CAS 274-00-0C5H3N3S
2-Methylthiazolo[4,5-b]pyrazine chemical structure, C6H5N3S, CAS 87444-21-1
2-Methylthiazolo[4,5-b]pyrazine
CAS 87444-21-1C6H5N3S
Thiazolo[4,5-B]pyrazine, trimethyl-(9CI) chemical structure, C8H9N3S, CAS 87444-32-4
Thiazolo[4,5-B]pyrazine, trimethyl-(9CI)
CAS 87444-32-4C8H9N3S
6-Bromothiazolo[5,4-b]pyrazine chemical structure, C5H2BrN3S, CAS 87444-40-4
6-Bromothiazolo[5,4-b]pyrazine
CAS 87444-40-4C5H2BrN3S
6-Chloro-2-methyl-(1,3)thiazolo(4,5-b)pyrazine chemical structure, C6H4ClN3S, CAS 1292369-28-8
6-Chloro-2-methyl-(1,3)thiazolo(4,5-b)pyrazine
CAS 1292369-28-8C6H4ClN3S
2-Chloro-[1,3]thiazolo[4,5-b]pyrazine chemical structure, C5H2ClN3S, CAS 1190927-25-3
2-Chloro-[1,3]thiazolo[4,5-b]pyrazine
CAS 1190927-25-3C5H2ClN3S
Dimethyl (6-bromothiazolo[4,5-b]pyrazin-2-yl)carbonimidodithioate chemical structure, C8H7BrN4S3, CAS 1192814-60-0
Dimethyl (6-bromothiazolo[4,5-b]pyrazin-2-yl)carbonimidodithioate
CAS 1192814-60-0C8H7BrN4S3
6-Bromo-2-chloro-[1,3]thiazolo[4,5-b]pyrazine chemical structure, C5HBrClN3S, CAS 1221932-29-1
6-Bromo-2-chloro-[1,3]thiazolo[4,5-b]pyrazine
CAS 1221932-29-1C5HBrClN3S
Dimethyl (6-methylthiazolo[4,5-b]pyrazin-2-yl)carbonimidodithioate chemical structure, C9H10N4S3, CAS 1221974-34-0
Dimethyl (6-methylthiazolo[4,5-b]pyrazin-2-yl)carbonimidodithioate
CAS 1221974-34-0C9H10N4S3
6-Methylthiazolo[4,5-b]pyrazin-2-amine chemical structure, C6H6N4S, CAS 1221974-33-9
6-Methylthiazolo[4,5-b]pyrazin-2-amine
CAS 1221974-33-9C6H6N4S
Ethyl (6-ethynyl[1,3]thiazolo[4,5-b]pyrazin-2-yl)carbamate chemical structure, C10H8N4O2S, CAS 1220449-32-0
Ethyl (6-ethynyl[1,3]thiazolo[4,5-b]pyrazin-2-yl)carbamate
CAS 1220449-32-0C10H8N4O2S
6-Bromo-N-isopropyl[1,3]thiazolo[4,5-b]pyrazin-2-amine chemical structure, C8H9BrN4S, CAS 1400636-74-9
6-Bromo-N-isopropyl[1,3]thiazolo[4,5-b]pyrazin-2-amine
CAS 1400636-74-9C8H9BrN4S
6-Bromo-N-ethyl[1,3]thiazolo[4,5-b]pyrazin-2-amine chemical structure, C7H7BrN4S, CAS 1400635-41-7
6-Bromo-N-ethyl[1,3]thiazolo[4,5-b]pyrazin-2-amine
CAS 1400635-41-7C7H7BrN4S
5-Bromothiazolo[4,5-b]pyrazin-2-amine chemical structure, C5H3BrN4S, CAS 1256785-29-1
5-Bromothiazolo[4,5-b]pyrazin-2-amine
CAS 1256785-29-1C5H3BrN4S