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Murcko scaffold

Ring system with 3 rings and 27 atoms

42 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
42
With full pages
37
Scaffold SMILES

O=C(Oc1ccc(C=NNC(=S)Nc2ccccc2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Oc1ccc(C=NNC(=S)Nc2ccccc2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

2-Ethoxy-4-[[2-[[(4-methoxyphenyl)amino]thioxomethyl]hydrazinylidene]methyl]phenyl 2,4-dichlorobenzoate chemical structure, C24H21Cl2N3O4S, CAS 883572-51-8
2-Ethoxy-4-[[2-[[(4-methoxyphenyl)amino]thioxomethyl]hydrazinylidene]methyl]phenyl 2,4-dichlorobenzoate
CAS 883572-51-8C24H21Cl2N3O4S
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 2-fluorobenzoate chemical structure, C22H18FN3O2S, CAS 767314-19-2
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 2-fluorobenzoate
CAS 767314-19-2C22H18FN3O2S
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 2-bromobenzoate chemical structure, C22H18BrN3O2S, CAS 769152-38-7
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 2-bromobenzoate
CAS 769152-38-7C22H18BrN3O2S
4-(2-(Anilinocarbothioyl)carbohydrazonoyl)-2-methoxyphenyl 4-butoxybenzoate chemical structure, C26H27N3O4S, CAS 765274-42-8
4-(2-(Anilinocarbothioyl)carbohydrazonoyl)-2-methoxyphenyl 4-butoxybenzoate
CAS 765274-42-8C26H27N3O4S
4-(2-(Anilinocarbothioyl)carbohydrazonoyl)-2-methoxyphenyl 4-methylbenzoate chemical structure, C23H21N3O3S, CAS 769146-99-8
4-(2-(Anilinocarbothioyl)carbohydrazonoyl)-2-methoxyphenyl 4-methylbenzoate
CAS 769146-99-8C23H21N3O3S
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 4-methoxybenzoate chemical structure, C23H21N3O3S, CAS 767313-96-2
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 4-methoxybenzoate
CAS 767313-96-2C23H21N3O3S
2-Methoxy-4-(2-(3-toluidinocarbothioyl)carbohydrazonoyl)phenyl 2-chlorobenzoate chemical structure, C23H20ClN3O3S, CAS 769153-95-9
2-Methoxy-4-(2-(3-toluidinocarbothioyl)carbohydrazonoyl)phenyl 2-chlorobenzoate
CAS 769153-95-9C23H20ClN3O3S
4-(2-(Anilinocarbothioyl)carbohydrazonoyl)-2-methoxyphenyl 3-bromobenzoate chemical structure, C22H18BrN3O3S, CAS 769149-30-6
4-(2-(Anilinocarbothioyl)carbohydrazonoyl)-2-methoxyphenyl 3-bromobenzoate
CAS 769149-30-6C22H18BrN3O3S
4-{(E)-[2-(Anilinocarbothioyl)hydrazono]methyl}phenyl 3,4-dimethoxybenzoate chemical structure, C23H21N3O4S, CAS 767288-44-8
4-{(E)-[2-(Anilinocarbothioyl)hydrazono]methyl}phenyl 3,4-dimethoxybenzoate
CAS 767288-44-8C23H21N3O4S
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate chemical structure, C24H23N3O4S, CAS 769149-42-0
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate
CAS 769149-42-0C24H23N3O4S
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)phenyl 4-methoxybenzoate chemical structure, C22H18ClN3O3S, CAS 769146-52-3
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)phenyl 4-methoxybenzoate
CAS 769146-52-3C22H18ClN3O3S
4-(2-((4-Fluoroanilino)carbothioyl)carbohydrazonoyl)phenyl 2-bromobenzoate chemical structure, C21H15BrFN3O2S, CAS 769155-98-8
4-(2-((4-Fluoroanilino)carbothioyl)carbohydrazonoyl)phenyl 2-bromobenzoate
CAS 769155-98-8C21H15BrFN3O2S
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)-2-meo-PH 4-methylbenzoate chemical structure, C23H20ClN3O3S, CAS 764692-69-5
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)-2-meo-PH 4-methylbenzoate
CAS 764692-69-5C23H20ClN3O3S
4-{(E)-[2-(Anilinocarbothioyl)hydrazono]methyl}phenyl 2-methylbenzoate chemical structure, C22H19N3O2S, CAS 769146-36-3
4-{(E)-[2-(Anilinocarbothioyl)hydrazono]methyl}phenyl 2-methylbenzoate
CAS 769146-36-3C22H19N3O2S
2-Ethoxy-4-(2-((4-F-anilino)carbothioyl)carbohydrazonoyl)PH 4-methoxybenzoate chemical structure, C24H22FN3O4S, CAS 767305-78-2
2-Ethoxy-4-(2-((4-F-anilino)carbothioyl)carbohydrazonoyl)PH 4-methoxybenzoate
CAS 767305-78-2C24H22FN3O4S
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 4-butoxybenzoate chemical structure, C26H27N3O3S, CAS 765275-12-5
4-(2-(3-Toluidinocarbothioyl)carbohydrazonoyl)phenyl 4-butoxybenzoate
CAS 765275-12-5C26H27N3O3S
4-{(E)-[2-(3-Toluidinocarbothioyl)hydrazono]methyl}phenyl 4-propoxybenzoate chemical structure, C25H25N3O3S, CAS 767312-24-3
4-{(E)-[2-(3-Toluidinocarbothioyl)hydrazono]methyl}phenyl 4-propoxybenzoate
CAS 767312-24-3C25H25N3O3S
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate chemical structure, C23H20ClN3O4S, CAS 767320-31-0
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate
CAS 767320-31-0C23H20ClN3O4S
2-Methoxy-4-(2-(3-toluidinocarbothioyl)carbohydrazonoyl)phenyl 3-bromobenzoate chemical structure, C23H20BrN3O3S, CAS 769152-24-1
2-Methoxy-4-(2-(3-toluidinocarbothioyl)carbohydrazonoyl)phenyl 3-bromobenzoate
CAS 769152-24-1C23H20BrN3O3S
2-Ethoxy-4-(2-(3-toluidinocarbothioyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C24H22ClN3O3S, CAS 769153-97-1
2-Ethoxy-4-(2-(3-toluidinocarbothioyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 769153-97-1C24H22ClN3O3S
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)-2-meo-PH 4-butoxybenzoate chemical structure, C26H26ClN3O4S, CAS 764692-68-4
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)-2-meo-PH 4-butoxybenzoate
CAS 764692-68-4C26H26ClN3O4S
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)phenyl 2-bromobenzoate chemical structure, C21H15BrClN3O2S, CAS 769152-35-4
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)phenyl 2-bromobenzoate
CAS 769152-35-4C21H15BrClN3O2S
4-(2-(Anilinocarbothioyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C21H15Cl2N3O2S, CAS 340223-59-8
4-(2-(Anilinocarbothioyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 340223-59-8C21H15Cl2N3O2S
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)phenyl 4-propoxybenzoate chemical structure, C24H22ClN3O3S, CAS 767313-95-1
4-(2-((3-Chloroanilino)carbothioyl)carbohydrazonoyl)phenyl 4-propoxybenzoate
CAS 767313-95-1C24H22ClN3O3S