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Murcko scaffold

Ring system with 3 rings and 27 atoms

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
22
With full pages
19
Scaffold SMILES

O=C(Cc1ccccc1)NN=Cc1ccc(OC(=O)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)NN=Cc1ccc(OC(=O)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

4-{(E)-[2-(Phenylacetyl)hydrazinylidene]methyl}phenyl benzoate chemical structure, C22H18N2O3, CAS 341973-60-2
4-{(E)-[2-(Phenylacetyl)hydrazinylidene]methyl}phenyl benzoate
CAS 341973-60-2C22H18N2O3
4-(2-(HO(Phenyl)acetyl)carbohydrazonoyl)-2-methoxyphenyl 2,4-dichlorobenzoate chemical structure, C23H18Cl2N2O5, CAS 328571-72-8
4-(2-(HO(Phenyl)acetyl)carbohydrazonoyl)-2-methoxyphenyl 2,4-dichlorobenzoate
CAS 328571-72-8C23H18Cl2N2O5
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 2-bromobenzoate chemical structure, C22H17BrN2O4, CAS 342778-06-7
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 2-bromobenzoate
CAS 342778-06-7C22H17BrN2O4
4-(2-(Phenylacetyl)carbohydrazonoyl)phenyl 2-bromobenzoate chemical structure, C22H17BrN2O3, CAS 683253-54-5
4-(2-(Phenylacetyl)carbohydrazonoyl)phenyl 2-bromobenzoate
CAS 683253-54-5C22H17BrN2O3
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl benzoate chemical structure, C24H22N2O5, CAS 392730-53-9
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl benzoate
CAS 392730-53-9C24H22N2O5
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate chemical structure, C22H16Cl2N2O4, CAS 303131-22-8
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 2,4-dichlorobenzoate
CAS 303131-22-8C22H16Cl2N2O4
2-Methoxy-4-(2-(phenylacetyl)carbohydrazonoyl)phenyl 4-propoxybenzoate chemical structure, C26H26N2O5, CAS 765275-80-7
2-Methoxy-4-(2-(phenylacetyl)carbohydrazonoyl)phenyl 4-propoxybenzoate
CAS 765275-80-7C26H26N2O5
4-(2-(Phenylacetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate chemical structure, C24H22N2O4, CAS 767320-54-7
4-(2-(Phenylacetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate
CAS 767320-54-7C24H22N2O4
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate chemical structure, C24H22N2O6, CAS 764692-58-2
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 3,4-dimethoxybenzoate
CAS 764692-58-2C24H22N2O6
2-Ethoxy-4-(2-(phenylacetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate chemical structure, C26H26N2O5, CAS 765276-51-5
2-Ethoxy-4-(2-(phenylacetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate
CAS 765276-51-5C26H26N2O5
2-Methoxy-4-(2-(phenylacetyl)carbohydrazonoyl)phenyl 2-chlorobenzoate chemical structure, C23H19ClN2O4, CAS 341973-66-8
2-Methoxy-4-(2-(phenylacetyl)carbohydrazonoyl)phenyl 2-chlorobenzoate
CAS 341973-66-8C23H19ClN2O4
2-Ethoxy-4-{(E)-[(phenylacetyl)hydrazono]methyl}phenyl 2,4-dichlorobenzoate chemical structure, C24H20Cl2N2O4, CAS 357300-63-1
2-Ethoxy-4-{(E)-[(phenylacetyl)hydrazono]methyl}phenyl 2,4-dichlorobenzoate
CAS 357300-63-1C24H20Cl2N2O4
4-{(E)-[2-(2-Hydroxy-2-phenylacetyl)hydrazono]methyl}phenyl 4-ethoxybenzoate chemical structure, C24H22N2O5, CAS 769146-39-6
4-{(E)-[2-(2-Hydroxy-2-phenylacetyl)hydrazono]methyl}phenyl 4-ethoxybenzoate
CAS 769146-39-6C24H22N2O5
2-Methoxy-4-(2-(phenylacetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate chemical structure, C25H24N2O5, CAS 767332-54-7
2-Methoxy-4-(2-(phenylacetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate
CAS 767332-54-7C25H24N2O5
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 3-methylbenzoate chemical structure, C23H20N2O4, CAS 765296-87-5
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 3-methylbenzoate
CAS 765296-87-5C23H20N2O4
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 4-propoxybenzoate chemical structure, C27H28N2O6, CAS 767308-20-3
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 4-propoxybenzoate
CAS 767308-20-3C27H28N2O6
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate chemical structure, C26H26N2O6, CAS 765911-94-2
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 4-ethoxybenzoate
CAS 765911-94-2C26H26N2O6
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)-2-methoxyphenyl 4-ethoxybenzoate chemical structure, C25H24N2O6, CAS 765907-68-4
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)-2-methoxyphenyl 4-ethoxybenzoate
CAS 765907-68-4C25H24N2O6
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 2,4-DI-CL-benzoate chemical structure, C24H20Cl2N2O5, CAS 882037-64-1
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 2,4-DI-CL-benzoate
CAS 882037-64-1C24H20Cl2N2O5
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate chemical structure, C24H21ClN2O5, CAS 882037-76-5
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 4-chlorobenzoate
CAS 882037-76-5C24H21ClN2O5
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 4-methoxybenzoate chemical structure, C25H24N2O6, CAS 881456-47-9
2-Ethoxy-4-(2-(hydroxy(phenyl)acetyl)carbohydrazonoyl)phenyl 4-methoxybenzoate
CAS 881456-47-9C25H24N2O6
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)-2-methoxyphenyl 2-chlorobenzoate chemical structure, C23H19ClN2O5, CAS 553629-54-2
4-(2-(Hydroxy(phenyl)acetyl)carbohydrazonoyl)-2-methoxyphenyl 2-chlorobenzoate
CAS 553629-54-2C23H19ClN2O5