CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
12
With full pages
6
Scaffold SMILES

O=C(Cn1nnc2ccccc21)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1nnc2ccccc21)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

2-(Benzotriazol-1-yl)-N-[(E)-(2-methylphenyl)methylideneamino]acetamide chemical structure, C16H15N5O, CAS 315211-06-4
2-(Benzotriazol-1-yl)-N-[(E)-(2-methylphenyl)methylideneamino]acetamide
CAS 315211-06-4C16H15N5O
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(3,4-dimethoxybenzylidene)acetohydrazide chemical structure, C17H17N5O3, CAS 1029014-13-8
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(3,4-dimethoxybenzylidene)acetohydrazide
CAS 1029014-13-8C17H17N5O3
2-(1H-1,2,3-Benzotriazol-1-yl)-N'-[(1E)-1-phenylethylidene]acetohydrazide chemical structure, C16H15N5O, CAS 294649-46-0
2-(1H-1,2,3-Benzotriazol-1-yl)-N'-[(1E)-1-phenylethylidene]acetohydrazide
CAS 294649-46-0C16H15N5O
2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3,4-dimethoxybenzylidene)propanohydrazide chemical structure, C18H19N5O3, CAS 354542-45-3
2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3,4-dimethoxybenzylidene)propanohydrazide
CAS 354542-45-3C18H19N5O3
2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3-methoxybenzylidene)propanohydrazide chemical structure, C17H17N5O2, CAS 342039-21-8
2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3-methoxybenzylidene)propanohydrazide
CAS 342039-21-8C17H17N5O2
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(2-bromobenzylidene)acetohydrazide chemical structure, C15H12BrN5O, CAS 305353-46-2
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(2-bromobenzylidene)acetohydrazide
CAS 305353-46-2C15H12BrN5O
2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3-bromobenzylidene)propanohydrazide chemical structure, C16H14BrN5O, CAS 342038-86-2
2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3-bromobenzylidene)propanohydrazide
CAS 342038-86-2C16H14BrN5O
2-(1H-Benzotriazol-1-yl)-N'-[(E)-(2-hydroxy-3-methoxy-5-nitrophenyl)methylidene]acetohydrazide chemical structure, C16H14N6O5, CAS 345327-88-0
2-(1H-Benzotriazol-1-yl)-N'-[(E)-(2-hydroxy-3-methoxy-5-nitrophenyl)methylidene]acetohydrazide
CAS 345327-88-0C16H14N6O5
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(4-hydroxy-3-methoxybenzylidene)acetohydrazide chemical structure, C16H15N5O3, CAS 305353-54-2
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(4-hydroxy-3-methoxybenzylidene)acetohydrazide
CAS 305353-54-2C16H15N5O3
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(5-bromo-2-hydroxybenzylidene)acetohydrazide chemical structure, C15H12BrN5O2, CAS 305353-36-0
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(5-bromo-2-hydroxybenzylidene)acetohydrazide
CAS 305353-36-0C15H12BrN5O2
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(3,5-dibromo-2-hydroxybenzylidene)acetohydrazide chemical structure, C15H11Br2N5O2, CAS 315210-96-9
(E)-2-(1H-Benzo[d][1,2,3]triazol-1-yl)-N'-(3,5-dibromo-2-hydroxybenzylidene)acetohydrazide
CAS 315210-96-9C15H11Br2N5O2
(E)-N'-(3-Allyl-2-hydroxybenzylidene)-2-(1H-benzo[d][1,2,3]triazol-1-yl)acetohydrazide chemical structure, C18H17N5O2, CAS 305353-64-4
(E)-N'-(3-Allyl-2-hydroxybenzylidene)-2-(1H-benzo[d][1,2,3]triazol-1-yl)acetohydrazide
CAS 305353-64-4C18H17N5O2