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Murcko scaffold

Ring system with 3 rings and 21 atoms

77 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
77
With full pages
6
Scaffold SMILES

O=C(COc1ccccc1)N=Nc1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)N=Nc1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

3-(Phenoxyacetylhydrazono)-2-indolinone chemical structure, C16H13N3O3, CAS 154910-40-4
3-(Phenoxyacetylhydrazono)-2-indolinone
CAS 154910-40-4C16H13N3O3
3-((m-Methylphenoxyacetyhdrazono)-2-indolinone chemical structure, C17H15N3O3, CAS 154910-41-5
3-((m-Methylphenoxyacetyhdrazono)-2-indolinone
CAS 154910-41-5C17H15N3O3
N'-(5,7-Dibromo-2-oxoindolin-3-ylidene)-2-(2-isopropyl-5-methylphenoxy)acethydrazide chemical structure, C20H19Br2N3O3, CAS 327033-93-2
N'-(5,7-Dibromo-2-oxoindolin-3-ylidene)-2-(2-isopropyl-5-methylphenoxy)acethydrazide
CAS 327033-93-2C20H19Br2N3O3
3-(2-(4-Ethylphenoxy)acetylhydrazidyl)-2-oxoindoline chemical structure, C18H17N3O3, CAS 290835-24-4
3-(2-(4-Ethylphenoxy)acetylhydrazidyl)-2-oxoindoline
CAS 290835-24-4C18H17N3O3
(E)-2-(4-Chlorophenoxy)-N'-(2-oxoindolin-3-ylidene)acetohydrazide chemical structure, C16H12ClN3O3, CAS 125298-99-9
(E)-2-(4-Chlorophenoxy)-N'-(2-oxoindolin-3-ylidene)acetohydrazide
CAS 125298-99-9C16H12ClN3O3
(E)-N'-(2-Oxoindolin-3-ylidene)-2-(p-tolyloxy)acetohydrazide chemical structure, C17H15N3O3, CAS 125299-00-5
(E)-N'-(2-Oxoindolin-3-ylidene)-2-(p-tolyloxy)acetohydrazide
CAS 125299-00-5C17H15N3O3
3-(2-(4-Methoxyphenoxy)acetylhydrazidyl)-2-oxoindoline chemical structure, C17H15N3O4, CAS 328541-34-0
3-(2-(4-Methoxyphenoxy)acetylhydrazidyl)-2-oxoindoline
CAS 328541-34-0C17H15N3O4
2-(2-Methylphenoxy)-N'-[(3Z)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetohydrazide chemical structure, C17H15N3O3, CAS 125299-01-6
2-(2-Methylphenoxy)-N'-[(3Z)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetohydrazide
CAS 125299-01-6C17H15N3O3
2-(4-Chloro-2-methylphenoxy)-N'-[(3E)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetohydrazide chemical structure, C17H14ClN3O3, CAS 321966-67-0
2-(4-Chloro-2-methylphenoxy)-N'-[(3E)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetohydrazide
CAS 321966-67-0C17H14ClN3O3
2-(4-Methoxyphenoxy)-N-[(Z)-(1-methyl-2-oxo-indolin-3-ylidene)amino]acetamide chemical structure, C18H17N3O4, CAS 382161-27-5
2-(4-Methoxyphenoxy)-N-[(Z)-(1-methyl-2-oxo-indolin-3-ylidene)amino]acetamide
CAS 382161-27-5C18H17N3O4
2-(2-Chlorophenoxy)-N'-[(3E)-1-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetohydrazide chemical structure, C17H14ClN3O3, CAS 331656-75-8
2-(2-Chlorophenoxy)-N'-[(3E)-1-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetohydrazide
CAS 331656-75-8C17H14ClN3O3
3-(2-(2-Chlorophenoxy)acetylhydrazidyl)-2-oxoindoline chemical structure, C16H12ClN3O3, CAS 125299-05-0
3-(2-(2-Chlorophenoxy)acetylhydrazidyl)-2-oxoindoline
CAS 125299-05-0C16H12ClN3O3
N-(Aza(2-oxoindolin-3-ylidene)methyl)-2-(4-nitrophenoxy)ethanamide chemical structure, C16H12N4O5, CAS 81215-48-7
N-(Aza(2-oxoindolin-3-ylidene)methyl)-2-(4-nitrophenoxy)ethanamide
CAS 81215-48-7C16H12N4O5
2-(2,4-Dichlorophenoxy)-N'-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetohydrazide chemical structure, C16H11Cl2N3O3, CAS 325475-79-4
2-(2,4-Dichlorophenoxy)-N'-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetohydrazide
CAS 325475-79-4C16H11Cl2N3O3
N'-(4-Bromo-5-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-phenoxyacetohydrazide chemical structure, C17H14BrN3O3, CAS 5214-83-5
N'-(4-Bromo-5-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-phenoxyacetohydrazide
CAS 5214-83-5C17H14BrN3O3
N'-[(3Z)-5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-2-(4-chlorophenoxy)acetohydrazide chemical structure, C16H11BrClN3O3, CAS 84816-33-1
N'-[(3Z)-5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-2-(4-chlorophenoxy)acetohydrazide
CAS 84816-33-1C16H11BrClN3O3
N'-[(3Z)-5,7-Dibromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-2-(2,4-dichlorophenoxy)acetohydrazide chemical structure, C16H9Br2Cl2N3O3, CAS 5225-78-5
N'-[(3Z)-5,7-Dibromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-2-(2,4-dichlorophenoxy)acetohydrazide
CAS 5225-78-5C16H9Br2Cl2N3O3
N-(5-Bromo-2-hydroxy-1-methylindol-3-yl)imino-2-(5-methyl-2-propan-2-ylphenoxy)acetamide chemical structure, C21H22BrN3O3, CAS 297137-70-3
N-(5-Bromo-2-hydroxy-1-methylindol-3-yl)imino-2-(5-methyl-2-propan-2-ylphenoxy)acetamide
CAS 297137-70-3C21H22BrN3O3
(E)-N'-(5,7-Dibromo-2-oxoindolin-3-ylidene)-2-(4-methoxyphenoxy)acetohydrazide chemical structure, C17H13Br2N3O4, CAS 328541-35-1
(E)-N'-(5,7-Dibromo-2-oxoindolin-3-ylidene)-2-(4-methoxyphenoxy)acetohydrazide
CAS 328541-35-1C17H13Br2N3O4
(Z)-N'-(5-Bromo-2-oxoindolin-3-ylidene)-2-(o-tolyloxy)acetohydrazide chemical structure, C17H14BrN3O3, CAS 303127-44-8
(Z)-N'-(5-Bromo-2-oxoindolin-3-ylidene)-2-(o-tolyloxy)acetohydrazide
CAS 303127-44-8C17H14BrN3O3
5-Bromo-3-(2-(2-chlorophenoxy)acetylhydrazidyl)-2-oxoindoline chemical structure, C16H11BrClN3O3, CAS 330572-72-0
5-Bromo-3-(2-(2-chlorophenoxy)acetylhydrazidyl)-2-oxoindoline
CAS 330572-72-0C16H11BrClN3O3
2-(4-Bromophenoxy)-N'-[(3E)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]acetohydrazide chemical structure, C16H12BrN3O3, CAS 299165-91-6
2-(4-Bromophenoxy)-N'-[(3E)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]acetohydrazide
CAS 299165-91-6C16H12BrN3O3
(E)-N'-(5-Bromo-2-oxoindolin-3-ylidene)-2-phenoxyacetohydrazide chemical structure, C16H12BrN3O3, CAS 84816-32-0
(E)-N'-(5-Bromo-2-oxoindolin-3-ylidene)-2-phenoxyacetohydrazide
CAS 84816-32-0C16H12BrN3O3
2-(2-Bromo-4,6-dimethylphenoxy)-N'-(1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetohydrazide chemical structure, C20H20BrN3O3, CAS 328913-73-1
2-(2-Bromo-4,6-dimethylphenoxy)-N'-(1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetohydrazide
CAS 328913-73-1C20H20BrN3O3