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Murcko scaffold

Ring system with 4 rings and 24 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
8
With full pages
1
Scaffold SMILES

O=C1C(=Cc2ccccc2)C(c2ccccc2)Oc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=Cc2ccccc2)C(c2ccccc2)Oc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

3-[(2-Nitrophenyl)methylidene]-2-phenylchromen-4-one chemical structure, C22H15NO4, CAS 6327-80-6
3-[(2-Nitrophenyl)methylidene]-2-phenylchromen-4-one
CAS 6327-80-6C22H15NO4
(3Z)-3-[(4-Bromophenyl)methylidene]-2-phenylchromen-4-one chemical structure, C22H15BrO2, CAS 112014-60-5
(3Z)-3-[(4-Bromophenyl)methylidene]-2-phenylchromen-4-one
CAS 112014-60-5C22H15BrO2
3-(4-Ethoxybenzylidene)-2-phenyl-2,3-dihydro-4H-chromen-4-one chemical structure, C24H20O3, CAS 155131-00-3
3-(4-Ethoxybenzylidene)-2-phenyl-2,3-dihydro-4H-chromen-4-one
CAS 155131-00-3C24H20O3
3-(2-Nitrobenzylidene)-2-phenylchroman-4-one chemical structure, C22H15NO4
3-(2-Nitrobenzylidene)-2-phenylchroman-4-one
C22H15NO4
2,3-Dihydro-3-(3-hydroxybenzylidene)flavone chemical structure, C22H16O3, CAS 67570-40-5
2,3-Dihydro-3-(3-hydroxybenzylidene)flavone
CAS 67570-40-5C22H16O3
(3E)-3-[(2-Nitrophenyl)methylidene]-2-phenylchromen-4-one chemical structure, C22H15NO4
(3E)-3-[(2-Nitrophenyl)methylidene]-2-phenylchromen-4-one
C22H15NO4
[(3E)-2-(4-Methoxyphenyl)-3-[(4-methoxyphenyl)methylidene]-4-oxochromen-6-yl] dihydrogen phosphate chemical structure, C24H21O8P, CAS 119413-57-9
[(3E)-2-(4-Methoxyphenyl)-3-[(4-methoxyphenyl)methylidene]-4-oxochromen-6-yl] dihydrogen phosphate
CAS 119413-57-9C24H21O8P
Lyase, citrate chemical structure, C66H40Cl6F2O9, CAS 9012-83-3
Lyase, citrate
CAS 9012-83-3C66H40Cl6F2O9