Murcko scaffold
4-(1-Benzylbenzimidazol-2-yl)-1-phenylpyrrolidin-2-one scaffold
107 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 28
- Chemicals
- 107
- With full pages
- 3
Scaffold SMILES
O=C1CC(c2nc3ccccc3n2Cc2ccccc2)CN1c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 107 chemicals
4-(1-Benzylbenzimidazol-2-yl)-1-phenylpyrrolidin-2-one
CAS 637322-15-7C24H21N3O
![4-[1-[(2-Fluorophenyl)methyl]benzimidazol-2-yl]-1-phenylpyrrolidin-2-one chemical structure, C24H20FN3O, CAS 637754-73-5](/s/ZDQAMGBZVJEZID-UHFFFAOYSA-N.svg)
4-[1-[(2-Fluorophenyl)methyl]benzimidazol-2-yl]-1-phenylpyrrolidin-2-one
CAS 637754-73-5C24H20FN3O
4-(1-Benzylbenzimidazol-2-yl)-1-(4-ethoxyphenyl)pyrrolidin-2-one
CAS 637322-17-9C26H25N3O2
![1-(2,4-Dimethylphenyl)-4-[1-[(4-methylphenyl)methyl]benzimidazol-2-yl]pyrrolidin-2-one chemical structure, C27H27N3O, CAS 708285-92-1](/s/PINFVJUTMWOGSJ-UHFFFAOYSA-N.svg)
1-(2,4-Dimethylphenyl)-4-[1-[(4-methylphenyl)methyl]benzimidazol-2-yl]pyrrolidin-2-one
CAS 708285-92-1C27H27N3O
![1-(2,4-Dimethylphenyl)-4-[1-[(2-methylphenyl)methyl]benzimidazol-2-yl]pyrrolidin-2-one chemical structure, C27H27N3O, CAS 709002-04-0](/s/RFJBOXILXRCHQF-UHFFFAOYSA-N.svg)
1-(2,4-Dimethylphenyl)-4-[1-[(2-methylphenyl)methyl]benzimidazol-2-yl]pyrrolidin-2-one
CAS 709002-04-0C27H27N3O
4-(1-Benzyl-1H-1,3-benzodiazol-2-yl)-1-(2-methylphenyl)pyrrolidin-2-one
CAS 577787-09-8C25H23N3O
![4-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(m-tolyl)pyrrolidin-2-one chemical structure, C25H22FN3O, CAS 847177-07-5](/s/HWRBFGOYOBZVPX-UHFFFAOYSA-N.svg)
4-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(m-tolyl)pyrrolidin-2-one
CAS 847177-07-5C25H22FN3O
![4-[1-[(4-Fluorophenyl)methyl]benzimidazol-2-yl]-1-(2-methoxyphenyl)pyrrolidin-2-one chemical structure, C25H22FN3O2, CAS 850735-99-8](/s/BVGVUOYMFVICDX-UHFFFAOYSA-N.svg)
4-[1-[(4-Fluorophenyl)methyl]benzimidazol-2-yl]-1-(2-methoxyphenyl)pyrrolidin-2-one
CAS 850735-99-8C25H22FN3O2
![4-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(o-tolyl)pyrrolidin-2-one chemical structure, C25H22FN3O, CAS 573974-88-6](/s/MEFYXGXCBDLLFL-UHFFFAOYSA-N.svg)
4-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(o-tolyl)pyrrolidin-2-one
CAS 573974-88-6C25H22FN3O
![4-(1-(2-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(p-tolyl)pyrrolidin-2-one chemical structure, C25H22FN3O, CAS 844448-37-9](/s/RAZXWEGHLYKBDP-UHFFFAOYSA-N.svg)
4-(1-(2-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(p-tolyl)pyrrolidin-2-one
CAS 844448-37-9C25H22FN3O
![4-(1-(4-Methylbenzyl)-1H-benzo[d]imidazol-2-yl)-1-(p-tolyl)pyrrolidin-2-one chemical structure, C26H25N3O, CAS 840496-43-7](/s/FKTJMEIPXFCFJI-UHFFFAOYSA-N.svg)
4-(1-(4-Methylbenzyl)-1H-benzo[d]imidazol-2-yl)-1-(p-tolyl)pyrrolidin-2-one
CAS 840496-43-7C26H25N3O
![4-(1-(4-Chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(3-methoxyphenyl)pyrrolidin-2-one chemical structure, C25H22ClN3O2, CAS 844858-03-3](/s/NBUUMQWGGAJHQQ-UHFFFAOYSA-N.svg)
4-(1-(4-Chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(3-methoxyphenyl)pyrrolidin-2-one
CAS 844858-03-3C25H22ClN3O2
![4-[1-(2-Methylbenzyl)-1H-benzimidazol-2-yl]-1-phenylpyrrolidin-2-one chemical structure, C25H23N3O, CAS 637754-66-6](/s/DPSXVQGIDKCCSY-UHFFFAOYSA-N.svg)
4-[1-(2-Methylbenzyl)-1H-benzimidazol-2-yl]-1-phenylpyrrolidin-2-one
CAS 637754-66-6C25H23N3O
![4-[1-(3-Methylbenzyl)-1H-benzimidazol-2-yl]-1-phenylpyrrolidin-2-one chemical structure, C25H23N3O, CAS 637754-67-7](/s/XHNUHXFFHLIKJY-UHFFFAOYSA-N.svg)
4-[1-(3-Methylbenzyl)-1H-benzimidazol-2-yl]-1-phenylpyrrolidin-2-one
CAS 637754-67-7C25H23N3O
![4-(1-(2-Chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(3-methoxyphenyl)pyrrolidin-2-one chemical structure, C25H22ClN3O2, CAS 844834-21-5](/s/ZTCGBWNJRGFJEO-UHFFFAOYSA-N.svg)
4-(1-(2-Chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(3-methoxyphenyl)pyrrolidin-2-one
CAS 844834-21-5C25H22ClN3O2
![1-(3-Methoxyphenyl)-4-(1-(4-methylbenzyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C26H25N3O2, CAS 842956-07-4](/s/XWKYOYYVWAOZGC-UHFFFAOYSA-N.svg)
1-(3-Methoxyphenyl)-4-(1-(4-methylbenzyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 842956-07-4C26H25N3O2
![4-(1-(4-Chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(2-methoxyphenyl)pyrrolidin-2-one chemical structure, C25H22ClN3O2, CAS 579440-28-1](/s/COKVFQXVIVPJSY-UHFFFAOYSA-N.svg)
4-(1-(4-Chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(2-methoxyphenyl)pyrrolidin-2-one
CAS 579440-28-1C25H22ClN3O2
![1-(4-Methoxyphenyl)-4-{1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazol-2-yl}pyrrolidin-2-one chemical structure, C26H25N3O2, CAS 844454-29-1](/s/XYVMFOBZCKPSDJ-UHFFFAOYSA-N.svg)
1-(4-Methoxyphenyl)-4-{1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazol-2-yl}pyrrolidin-2-one
CAS 844454-29-1C26H25N3O2
![4-(1-(2-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(o-tolyl)pyrrolidin-2-one chemical structure, C25H22FN3O, CAS 840517-08-0](/s/CEVIKXAWIKDHGV-UHFFFAOYSA-N.svg)
4-(1-(2-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(o-tolyl)pyrrolidin-2-one
CAS 840517-08-0C25H22FN3O
![4-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(p-tolyl)pyrrolidin-2-one chemical structure, C25H22FN3O, CAS 844464-78-4](/s/DLMORAPRGUFPPF-UHFFFAOYSA-N.svg)
4-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(p-tolyl)pyrrolidin-2-one
CAS 844464-78-4C25H22FN3O
![4-(1-(4-Chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(4-methoxyphenyl)pyrrolidin-2-one chemical structure, C25H22ClN3O2, CAS 862208-08-0](/s/ACNYPHBPSPDGNO-UHFFFAOYSA-N.svg)
4-(1-(4-Chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(4-methoxyphenyl)pyrrolidin-2-one
CAS 862208-08-0C25H22ClN3O2
![4-(1-(3-Methylbenzyl)-1H-benzo[d]imidazol-2-yl)-1-(p-tolyl)pyrrolidin-2-one chemical structure, C26H25N3O, CAS 573942-11-7](/s/QGPIIJOONWFFHO-UHFFFAOYSA-N.svg)
4-(1-(3-Methylbenzyl)-1H-benzo[d]imidazol-2-yl)-1-(p-tolyl)pyrrolidin-2-one
CAS 573942-11-7C26H25N3O
![1-(2-Methoxyphenyl)-4-(1-(4-methylbenzyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one chemical structure, C26H25N3O2, CAS 840485-39-4](/s/JRIZSAMQKBLQGM-UHFFFAOYSA-N.svg)
1-(2-Methoxyphenyl)-4-(1-(4-methylbenzyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one
CAS 840485-39-4C26H25N3O2
![4-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(4-methoxyphenyl)pyrrolidin-2-one chemical structure, C25H22FN3O2, CAS 848869-18-1](/s/UQCUBRVAKLLNER-UHFFFAOYSA-N.svg)
4-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(4-methoxyphenyl)pyrrolidin-2-one
CAS 848869-18-1C25H22FN3O2
- 4-(1-(2-Chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(2-methoxyphenyl)pyrrolidin-2-one848684-37-7C25H22ClN3O2
- 4-[1-(4-Methylbenzyl)-1H-benzimidazol-2-yl]-1-phenylpyrrolidin-2-one637754-68-8C25H23N3O
- 4-(1-(2-Methylbenzyl)-1H-benzo[d]imidazol-2-yl)-1-(p-tolyl)pyrrolidin-2-one845800-51-3C26H25N3O
- 4-(1-Benzyl-1H-benzo[d]imidazol-2-yl)-1-(4-methoxyphenyl)pyrrolidin-2-one847377-24-6C25H23N3O2
- 4-(1-(2-Methylbenzyl)-1H-benzo[d]imidazol-2-yl)-1-(m-tolyl)pyrrolidin-2-one848209-06-3C26H25N3O
- 1-Phenyl-4-[1-(1-phenylethyl)-1H-1,3-benzodiazol-2-yl]pyrrolidin-2-one637754-65-5C25H23N3O
- 4-{1-[(2,5-Dimethylphenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1-phenylpyrrolidin-2-one637754-71-3C26H25N3O
- 4-{1-[(2-Chlorophenyl)methyl]benzimidazol-2-yl}-1-phenylpyrrolidin-2-one637754-77-9C24H20ClN3O
- 4-[1-[(4-Chlorophenyl)methyl]benzimidazol-2-yl]-1-phenylpyrrolidin-2-one637754-81-5C24H20ClN3O
- 1-(3-Methoxyphenyl)-4-(1-(3-methylbenzyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one848221-18-1C26H25N3O2
- 4-(1-(2,5-Dimethylbenzyl)-1H-benzo[d]imidazol-2-yl)-1-(2-methoxyphenyl)pyrrolidin-2-one840479-25-6C27H27N3O2
- 4-(1-(2-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(3-methoxyphenyl)pyrrolidin-2-one847379-84-4C25H22FN3O2
- 1-(2-Methoxyphenyl)-4-(1-(2-methylbenzyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one846600-47-3C26H25N3O2
- 4-[1-[(2-Fluorophenyl)methyl]benzimidazol-2-yl]-1-(2-methoxyphenyl)pyrrolidin-2-one848729-11-3C25H22FN3O2
- 1-(3-Methoxyphenyl)-4-(1-(2-methylbenzyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one844664-57-9C26H25N3O2
- 4-(1-(2,5-Dimethylbenzyl)-1H-benzo[d]imidazol-2-yl)-1-(4-methoxyphenyl)pyrrolidin-2-one848867-51-6C27H27N3O2
- 4-(1-(2-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1-(m-tolyl)pyrrolidin-2-one848063-89-8C25H22FN3O
- 4-(1-Benzyl-1H-benzimidazol-2-yl)-1-(2,4-dimethylphenyl)pyrrolidin-2-one847394-33-6C26H25N3O
- 1-(2,4-Dimethylphenyl)-4-[1-[(2-fluorophenyl)methyl]benzimidazol-2-yl]pyrrolidin-2-one847394-34-7C26H24FN3O
- 4-(1-Benzylbenzimidazol-2-yl)-1-(4-ethylphenyl)pyrrolidin-2-one847394-67-6C26H25N3O
- 4-(1-Benzylbenzimidazol-2-yl)-1-(3,4-dimethylphenyl)pyrrolidin-2-one847394-88-1C26H25N3O
- 1-(3,4-Dimethylphenyl)-4-[1-[(2-fluorophenyl)methyl]benzimidazol-2-yl]pyrrolidin-2-one847394-89-2C26H24FN3O
- 1-(3,4-Dimethylphenyl)-4-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one847394-90-5C26H24FN3O
- 4-(1-Benzyl-1H-benzimidazol-2-yl)-1-(2,5-dimethylphenyl)pyrrolidin-2-one862828-16-8C26H25N3O