CompoundList
Sign in
Murcko scaffold

1-Benzyl-2-thiophen-2-ylbenzimidazole scaffold

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
8
With full pages
2
Scaffold SMILES

c1ccc(Cn2c(-c3cccs3)nc3ccccc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-2-thiophen-2-ylbenzimidazole page
Murcko scaffold c1ccc(Cn2c(-c3cccs3)nc3ccccc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

1-(3-Methylbenzyl)-2-thien-2-yl-1H-benzimidazole chemical structure, C19H16N2S, CAS 500273-04-1
1-(3-Methylbenzyl)-2-thien-2-yl-1H-benzimidazole
CAS 500273-04-1C19H16N2S
1-(4-Methylbenzyl)-2-(thiophen-2-yl)-1H-benzo[d]imidazole chemical structure, C19H16N2S, CAS 488090-16-0
1-(4-Methylbenzyl)-2-(thiophen-2-yl)-1H-benzo[d]imidazole
CAS 488090-16-0C19H16N2S
1-(4-Chlorobenzyl)-2-(thiophen-2-yl)-1H-benzo[d]imidazole chemical structure, C18H13ClN2S, CAS 488812-52-8
1-(4-Chlorobenzyl)-2-(thiophen-2-yl)-1H-benzo[d]imidazole
CAS 488812-52-8C18H13ClN2S
1-[(2-Fluorophenyl)methyl]-2-(thiophen-2-yl)-1H-1,3-benzodiazole chemical structure, C18H13FN2S, CAS 638140-59-7
1-[(2-Fluorophenyl)methyl]-2-(thiophen-2-yl)-1H-1,3-benzodiazole
CAS 638140-59-7C18H13FN2S
1-Benzyl-2-thiophen-2-ylbenzimidazole chemical structure, C18H14N2S, CAS 488813-95-2
1-Benzyl-2-thiophen-2-ylbenzimidazole
CAS 488813-95-2C18H14N2S
1-[(4-Fluorophenyl)methyl]-2-(thiophen-2-yl)-1H-1,3-benzodiazole chemical structure, C18H13FN2S, CAS 615281-45-3
1-[(4-Fluorophenyl)methyl]-2-(thiophen-2-yl)-1H-1,3-benzodiazole
CAS 615281-45-3C18H13FN2S
1-[(2-Methylphenyl)methyl]-2-(thiophen-2-yl)-1H-1,3-benzodiazole chemical structure, C19H16N2S, CAS 615281-43-1
1-[(2-Methylphenyl)methyl]-2-(thiophen-2-yl)-1H-1,3-benzodiazole
CAS 615281-43-1C19H16N2S
RefChem:382803 chemical structure, C19H15ClN2S, CAS 852956-06-0
RefChem:382803
CAS 852956-06-0C19H15ClN2S