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Murcko scaffold

Ring system with 4 rings and 25 atoms

17 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
17
With full pages
3
Scaffold SMILES

O=C(CC1C(=O)N(Cc2ccccc2)c2ccccc21)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CC1C(=O)N(Cc2ccccc2)c2ccccc21)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

1-(4-Chlorobenzyl)-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one chemical structure, C21H16ClNO4, CAS 1147208-40-9
1-(4-Chlorobenzyl)-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one
CAS 1147208-40-9C21H16ClNO4
1-(2-Chlorobenzyl)-3-[2-(2-furyl)-2-oxoethyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one chemical structure, C21H16ClNO4, CAS 355428-90-9
1-(2-Chlorobenzyl)-3-[2-(2-furyl)-2-oxoethyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one
CAS 355428-90-9C21H16ClNO4
3-[2-(Furan-2-yl)-2-oxoethyl]-3-hydroxy-1-[(2-methylphenyl)methyl]indol-2-one chemical structure, C22H19NO4, CAS 356081-07-7
3-[2-(Furan-2-yl)-2-oxoethyl]-3-hydroxy-1-[(2-methylphenyl)methyl]indol-2-one
CAS 356081-07-7C22H19NO4
1-Benzyl-3-hydroxy-3-[2-(5-methyl-2-furyl)-2-oxoethyl]-1,3-dihydro-2H-indol-2-one chemical structure, C22H19NO4, CAS 439092-02-1
1-Benzyl-3-hydroxy-3-[2-(5-methyl-2-furyl)-2-oxoethyl]-1,3-dihydro-2H-indol-2-one
CAS 439092-02-1C22H19NO4
1-Benzyl-5-bromo-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one chemical structure, C22H18BrNO4, CAS 439092-00-9
1-Benzyl-5-bromo-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one
CAS 439092-00-9C22H18BrNO4
5-Chloro-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxy-1-[(4-methylphenyl)methyl]indol-2-one chemical structure, C22H18ClNO4, CAS 688037-19-6
5-Chloro-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxy-1-[(4-methylphenyl)methyl]indol-2-one
CAS 688037-19-6C22H18ClNO4
1-[(3,4-Dimethoxyphenyl)methyl]-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one chemical structure, C24H23NO6, CAS 688333-80-4
1-[(3,4-Dimethoxyphenyl)methyl]-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one
CAS 688333-80-4C24H23NO6
1-[(3,4-Dimethoxyphenyl)methyl]-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one chemical structure, C23H21NO6, CAS 708243-11-2
1-[(3,4-Dimethoxyphenyl)methyl]-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one
CAS 708243-11-2C23H21NO6
1-Benzyl-5-bromo-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one chemical structure, C21H16BrNO4, CAS 689755-38-2
1-Benzyl-5-bromo-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one
CAS 689755-38-2C21H16BrNO4
5-Chloro-1-[(4-chlorophenyl)methyl]-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one chemical structure, C21H15Cl2NO4, CAS 690221-95-5
5-Chloro-1-[(4-chlorophenyl)methyl]-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one
CAS 690221-95-5C21H15Cl2NO4
1-Benzyl-5-chloro-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one chemical structure, C22H18ClNO4, CAS 690220-94-1
1-Benzyl-5-chloro-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one
CAS 690220-94-1C22H18ClNO4
1-(3-Fluorobenzyl)-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one chemical structure, C21H16FNO4, CAS 838895-48-0
1-(3-Fluorobenzyl)-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one
CAS 838895-48-0C21H16FNO4
1-(2,5-Dimethylbenzyl)-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one chemical structure, C23H21NO4, CAS 839685-57-3
1-(2,5-Dimethylbenzyl)-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxy-1,3-dihydro-2H-indol-2-one
CAS 839685-57-3C23H21NO4
1-[(2,4-Dimethylphenyl)methyl]-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one chemical structure, C23H21NO4, CAS 839690-53-8
1-[(2,4-Dimethylphenyl)methyl]-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one
CAS 839690-53-8C23H21NO4
1-Benzyl-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one chemical structure, C21H17NO4, CAS 353466-97-4
1-Benzyl-3-[2-(furan-2-yl)-2-oxoethyl]-3-hydroxyindol-2-one
CAS 353466-97-4C21H17NO4
1-[(2,4-Dimethylphenyl)methyl]-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one chemical structure, C24H23NO4, CAS 896649-20-0
1-[(2,4-Dimethylphenyl)methyl]-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one
CAS 896649-20-0C24H23NO4
1-[(4-Chlorophenyl)methyl]-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one chemical structure, C22H18ClNO4, CAS 688038-51-9
1-[(4-Chlorophenyl)methyl]-3-hydroxy-3-[2-(5-methylfuran-2-yl)-2-oxoethyl]indol-2-one
CAS 688038-51-9C22H18ClNO4