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Murcko scaffold

Ring system with 4 rings and 24 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
13
With full pages
1
Scaffold SMILES

c1ccc(-c2ccc(N3CCN(c4ncccn4)CC3)nn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccc(N3CCN(c4ncccn4)CC3)nn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Minozac free base chemical structure, C19H20N6, CAS 886208-65-7
Minozac free base
CAS 886208-65-7C19H20N6
4-Chloro-6-phenyl-3-(4-(pyrimidin-2-yl)piperazin-1-yl)pyridazine chemical structure, C18H17ClN6, CAS 886208-70-4
4-Chloro-6-phenyl-3-(4-(pyrimidin-2-yl)piperazin-1-yl)pyridazine
CAS 886208-70-4C18H17ClN6
2-(2-(4-(6-(4-Methoxyphenyl)-4,5-dimethylpyridazin-3-yl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)propan-2-ol chemical structure, C25H29F3N6O2, CAS 1204974-35-5
2-(2-(4-(6-(4-Methoxyphenyl)-4,5-dimethylpyridazin-3-yl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)propan-2-ol
CAS 1204974-35-5C25H29F3N6O2
Minozac chemical structure, C19H22Cl2N6, CAS 924909-75-1
Minozac
CAS 924909-75-1C19H22Cl2N6
3-(4-Fluorophenyl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine chemical structure, C18H17FN6, CAS 2337178-71-7
3-(4-Fluorophenyl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine
CAS 2337178-71-7C18H17FN6
3-[4-(5-Fluoropyrimidin-2-yl)piperazin-1-yl]-6-phenylpyridazine chemical structure, C18H17FN6, CAS 2380174-29-6
3-[4-(5-Fluoropyrimidin-2-yl)piperazin-1-yl]-6-phenylpyridazine
CAS 2380174-29-6C18H17FN6
3-[4-(4-Methylpyrimidin-2-yl)piperazin-1-yl]-6-phenylpyridazine chemical structure, C19H20N6, CAS 2331993-66-7
3-[4-(4-Methylpyrimidin-2-yl)piperazin-1-yl]-6-phenylpyridazine
CAS 2331993-66-7C19H20N6
3-[4-(5-Methylpyrimidin-2-yl)piperazin-1-yl]-6-phenylpyridazine chemical structure, C19H20N6, CAS 2380178-76-5
3-[4-(5-Methylpyrimidin-2-yl)piperazin-1-yl]-6-phenylpyridazine
CAS 2380178-76-5C19H20N6
3-(4-Fluorophenyl)-6-[4-(4-methylpyrimidin-2-yl)piperazin-1-yl]pyridazine chemical structure, C19H19FN6, CAS 2380081-01-4
3-(4-Fluorophenyl)-6-[4-(4-methylpyrimidin-2-yl)piperazin-1-yl]pyridazine
CAS 2380081-01-4C19H19FN6
3-(4-Ethoxyphenyl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine chemical structure, C20H22N6O, CAS 2380087-15-8
3-(4-Ethoxyphenyl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine
CAS 2380087-15-8C20H22N6O
3-(3-Fluorophenyl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine chemical structure, C18H17FN6, CAS 2380174-18-3
3-(3-Fluorophenyl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine
CAS 2380174-18-3C18H17FN6
3-(3-Fluorophenyl)-6-[4-(4-methylpyrimidin-2-yl)piperazin-1-yl]pyridazine chemical structure, C19H19FN6, CAS 2380141-85-3
3-(3-Fluorophenyl)-6-[4-(4-methylpyrimidin-2-yl)piperazin-1-yl]pyridazine
CAS 2380141-85-3C19H19FN6
3-(4-Ethoxyphenyl)-6-[4-(4-methylpyrimidin-2-yl)piperazin-1-yl]pyridazine chemical structure, C21H24N6O, CAS 2415634-43-2
3-(4-Ethoxyphenyl)-6-[4-(4-methylpyrimidin-2-yl)piperazin-1-yl]pyridazine
CAS 2415634-43-2C21H24N6O