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Murcko scaffold

Ring system with 2 rings and 8 atoms

75 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
75
With full pages
23
Scaffold SMILES

C1COB(C2CC2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1COB(C2CC2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 75 of 75 chemicals

rac-tert-Butyldimethyl{2-[(1R,2S)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl]ethoxy}silane chemical structure, C17H35BO3Si, CAS 2170724-18-0
rac-tert-Butyldimethyl{2-[(1R,2S)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl]ethoxy}silane
CAS 2170724-18-0C17H35BO3Si
4,4,5,5-Tetramethyl-2-[(1R,2R)-2-propan-2-ylcyclopropyl]-1,3,2-dioxaborolane chemical structure, C12H23BO2, CAS 2375816-13-8
4,4,5,5-Tetramethyl-2-[(1R,2R)-2-propan-2-ylcyclopropyl]-1,3,2-dioxaborolane
CAS 2375816-13-8C12H23BO2
2-((1R,2R)-2-Ethylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C11H21BO2, CAS 2375816-12-7
2-((1R,2R)-2-Ethylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 2375816-12-7C11H21BO2
2-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropane-1-carboxylic acid chemical structure, C10H17BO4, CAS 2769113-99-5
2-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropane-1-carboxylic acid
CAS 2769113-99-5C10H17BO4
2-(2,2-Difluorocyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C9H15BF2O2, CAS 2411405-92-8
2-(2,2-Difluorocyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 2411405-92-8C9H15BF2O2
rac-[(1R,2R)-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl]methanol chemical structure, C10H19BO3, CAS 2287240-96-2
rac-[(1R,2R)-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl]methanol
CAS 2287240-96-2C10H19BO3
2-[(1S,2S)-2-Ethylcyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C11H21BO2, CAS 2375816-24-1
2-[(1S,2S)-2-Ethylcyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 2375816-24-1C11H21BO2
2-((1S,2S)-2-Isopropylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C12H23BO2, CAS 2375816-28-5
2-((1S,2S)-2-Isopropylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 2375816-28-5C12H23BO2
rel-tert-Butyl (1R,2R)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropane-1-carboxylate chemical structure, C14H25BO4, CAS 2382719-62-0
rel-tert-Butyl (1R,2R)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropane-1-carboxylate
CAS 2382719-62-0C14H25BO4
rac-tert-Butyldimethyl{[(1R,2R)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl]methoxy}silane chemical structure, C16H33BO3Si, CAS 1424376-24-8
rac-tert-Butyldimethyl{[(1R,2R)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl]methoxy}silane
CAS 1424376-24-8C16H33BO3Si
2,2-Difluoro-1-methyl-cyclopropaneboronic acid pinacol ester chemical structure, C10H17BF2O2, CAS 3082750-26-0
2,2-Difluoro-1-methyl-cyclopropaneboronic acid pinacol ester
CAS 3082750-26-0C10H17BF2O2
4,4,5,5-Tetramethyl-2-[(1S,2S)-2-methylcyclopropyl]-1,3,2-dioxaborolane chemical structure, C10H19BO2, CAS 1417175-72-4
4,4,5,5-Tetramethyl-2-[(1S,2S)-2-methylcyclopropyl]-1,3,2-dioxaborolane
CAS 1417175-72-4C10H19BO2
4,4,5,5-Tetramethyl-2-[cis-2-methylcyclopropyl]-1,3,2-dioxaborolane chemical structure, C10H19BO2, CAS 1309366-00-4
4,4,5,5-Tetramethyl-2-[cis-2-methylcyclopropyl]-1,3,2-dioxaborolane
CAS 1309366-00-4C10H19BO2
2-((1S,2S)-2-(Difluoromethyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C10H17BF2O2, CAS 2766566-18-9
2-((1S,2S)-2-(Difluoromethyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 2766566-18-9C10H17BF2O2
2-((1S,2S)-2-(Fluoromethyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C10H18BFO2, CAS 2766566-87-2
2-((1S,2S)-2-(Fluoromethyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 2766566-87-2C10H18BFO2
2-(1-Ethenylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C11H19BO2, CAS 2412452-97-0
2-(1-Ethenylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 2412452-97-0C11H19BO2
cis-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropanecarboxylic acid chemical structure, C10H17BO4
cis-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropanecarboxylic acid
C10H17BO4
rel-2-((1R,2R)-2-Decylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C19H37BO2, CAS 925895-20-1
rel-2-((1R,2R)-2-Decylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS 925895-20-1C19H37BO2
tert-Butyldimethyl(((1S,2S)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)methoxy)silane chemical structure, C16H33BO3Si, CAS 2763710-15-0
tert-Butyldimethyl(((1S,2S)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)methoxy)silane
CAS 2763710-15-0C16H33BO3Si
trans-2-(Pivalamidomethyl)cyclopropylboronic Acid Pinacol Ester chemical structure, C30H56B2N2O6, CAS 1422542-02-6
trans-2-(Pivalamidomethyl)cyclopropylboronic Acid Pinacol Ester
CAS 1422542-02-6C30H56B2N2O6
(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)methanol chemical structure, C10H19BO3, CAS 2888707-66-0
(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)methanol
CAS 2888707-66-0C10H19BO3
N-(2-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)pivalamide chemical structure, C15H28BNO3, CAS 2241865-16-5
N-(2-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)pivalamide
CAS 2241865-16-5C15H28BNO3
rel-N-(((1R,2R)-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)methyl)pivalamide chemical structure, C15H28BNO3
rel-N-(((1R,2R)-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)methyl)pivalamide
C15H28BNO3
rel-((1R,2S)-2-Butyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)methanol chemical structure, C14H27BO3, CAS 2847906-42-5
rel-((1R,2S)-2-Butyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl)methanol
CAS 2847906-42-5C14H27BO3