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Murcko scaffold

Ring system with 3 rings and 13 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
21
With full pages
3
Scaffold SMILES

c1cc2cc3c(nc2s1)CCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc2cc3c(nc2s1)CCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile chemical structure, C12H11N3S, CAS 315248-92-1
3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile
CAS 315248-92-1C12H11N3S
3-Amino-N,N-diethyl-5,6,7,8-tetrahydrothieno(2,3-B)quinoline-2-carboxamide chemical structure, C16H21N3OS, CAS 400863-69-6
3-Amino-N,N-diethyl-5,6,7,8-tetrahydrothieno(2,3-B)quinoline-2-carboxamide
CAS 400863-69-6C16H21N3OS
3-Amino-5,6,7,8-tetrahydrothieno(2,3-b)quinoline-2-carboxamide chemical structure, C12H13N3OS, CAS 315248-91-0
3-Amino-5,6,7,8-tetrahydrothieno(2,3-b)quinoline-2-carboxamide
CAS 315248-91-0C12H13N3OS
AE-641/00355019 chemical structure, C11H12N2S, CAS 122914-50-5
AE-641/00355019
CAS 122914-50-5C11H12N2S
N-[(3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)carbonyl]glycine chemical structure, C14H15N3O3S, CAS 665001-30-9
N-[(3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)carbonyl]glycine
CAS 665001-30-9C14H15N3O3S
3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid chemical structure, C12H12N2O2S, CAS 352454-15-0
3-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid
CAS 352454-15-0C12H12N2O2S
Ethyl 3-amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate chemical structure, C14H16N2O2S, CAS 333769-64-5
Ethyl 3-amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate
CAS 333769-64-5C14H16N2O2S
3-Amino-6-ethyl-N-propan-2-yl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide chemical structure, C17H23N3OS, CAS 488095-88-1
3-Amino-6-ethyl-N-propan-2-yl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide
CAS 488095-88-1C17H23N3OS
Ethyl 3-amino-6-tert-butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate chemical structure, C18H24N2O2S, CAS 354793-47-8
Ethyl 3-amino-6-tert-butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate
CAS 354793-47-8C18H24N2O2S
3-Amino-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid chemical structure, C13H11F3N2O2S, CAS 610259-31-9
3-Amino-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid
CAS 610259-31-9C13H11F3N2O2S
3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile chemical structure, C14H15N3S, CAS 445382-05-8
3-Amino-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile
CAS 445382-05-8C14H15N3S
3-Amino-6-(tert-pentyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile chemical structure, C17H21N3S, CAS 665024-24-8
3-Amino-6-(tert-pentyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile
CAS 665024-24-8C17H21N3S
3-Amino-6-tert-butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile chemical structure, C16H19N3S, CAS 496785-43-4
3-Amino-6-tert-butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carbonitrile
CAS 496785-43-4C16H19N3S
4-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-5-ol chemical structure, C11H12N2OS, CAS 116481-91-5
4-Amino-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-5-ol
CAS 116481-91-5C11H12N2OS
3-Amino-6-ethyl-N-isopropyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide chemical structure, C18H22F3N3OS, CAS 939893-68-2
3-Amino-6-ethyl-N-isopropyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide
CAS 939893-68-2C18H22F3N3OS
2-({[3-Amino-6-ethyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]carbonyl}amino)acetic acid chemical structure, C17H18F3N3O3S, CAS 939893-70-6
2-({[3-Amino-6-ethyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]carbonyl}amino)acetic acid
CAS 939893-70-6C17H18F3N3O3S
Methyl 3-amino-6-tert-butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate chemical structure, C17H22N2O2S, CAS 354793-45-6
Methyl 3-amino-6-tert-butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate
CAS 354793-45-6C17H22N2O2S
6-tert-Butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline chemical structure, C15H19NS, CAS 910306-62-6
6-tert-Butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline
CAS 910306-62-6C15H19NS
Ethyl 3-amino-6-(trimethylsilyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate chemical structure, C17H24N2O2SSi, CAS 910307-34-5
Ethyl 3-amino-6-(trimethylsilyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate
CAS 910307-34-5C17H24N2O2SSi
(6-tert-Butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)urea chemical structure, C16H21N3OS, CAS 910306-80-8
(6-tert-Butyl-5,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl)urea
CAS 910306-80-8C16H21N3OS
N-Acetyl-N-(5,6,7,8-tetrahydrothieno[2,3-b]quinolin-4-yl)butanamide chemical structure, C17H20N2O2S, CAS 138299-97-5
N-Acetyl-N-(5,6,7,8-tetrahydrothieno[2,3-b]quinolin-4-yl)butanamide
CAS 138299-97-5C17H20N2O2S