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Murcko scaffold

Ring system with 1 ring and 7 atoms

25 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
25
With full pages
2
Scaffold SMILES

C=C1C=CC(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffold
Murcko scaffold C=C1C=CC(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

Methyl 2-(chloromethylidene)-4-(2-methoxy-2-oxoethyl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate chemical structure, C10H10ClNO5, CAS 77978-75-7
Methyl 2-(chloromethylidene)-4-(2-methoxy-2-oxoethyl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate
CAS 77978-75-7C10H10ClNO5
Magnesidin A chemical structure, C32H44MgN2O8, CAS 63593-55-5
Magnesidin A
CAS 63593-55-5C32H44MgN2O8
(Z)-2-(3-Ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanamide chemical structure, C9H10N2O2, CAS 1451878-43-5
(Z)-2-(3-Ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanamide
CAS 1451878-43-5C9H10N2O2
(2E)-2-(4-Ethenyl-3-methyl-5-oxopyrrol-2-ylidene)acetamide chemical structure, C9H10N2O2
(2E)-2-(4-Ethenyl-3-methyl-5-oxopyrrol-2-ylidene)acetamide
C9H10N2O2
1H-Pyrrole-3-carbonitrile, 2,5-dihydro-4-methyl-5-methylene-2-oxo- chemical structure, C7H6N2O, CAS 195155-69-2
1H-Pyrrole-3-carbonitrile, 2,5-dihydro-4-methyl-5-methylene-2-oxo-
CAS 195155-69-2C7H6N2O
Pulchellalactam chemical structure, C9H13NO, CAS 209802-54-0
Pulchellalactam
CAS 209802-54-0C9H13NO
1-Methyl-5-(propan-2-ylidene)-1,5-dihydro-2H-pyrrol-2-one chemical structure, C8H11NO, CAS 78210-72-7
1-Methyl-5-(propan-2-ylidene)-1,5-dihydro-2H-pyrrol-2-one
CAS 78210-72-7C8H11NO
3,4-Dimethyl-5-methylene-3-pyrrolin-2-one chemical structure, C7H9NO, CAS 89686-46-4
3,4-Dimethyl-5-methylene-3-pyrrolin-2-one
CAS 89686-46-4C7H9NO
5-Methylidene-1-prop-2-enylpyrrol-2-one chemical structure, C8H9NO, CAS 169170-66-5
5-Methylidene-1-prop-2-enylpyrrol-2-one
CAS 169170-66-5C8H9NO
(E)-3-Methyl-5-(2-methylpropylidene)-1H-pyrrol-2(5H)-one chemical structure, C9H13NO, CAS 713496-33-4
(E)-3-Methyl-5-(2-methylpropylidene)-1H-pyrrol-2(5H)-one
CAS 713496-33-4C9H13NO
(Z)-3-Methyl-5-(2-methylpropylidene)-1H-pyrrol-2(5H)-one chemical structure, C9H13NO, CAS 713496-32-3
(Z)-3-Methyl-5-(2-methylpropylidene)-1H-pyrrol-2(5H)-one
CAS 713496-32-3C9H13NO
2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-5-methylene- chemical structure, C7H9NO, CAS 78210-71-6
2H-Pyrrol-2-one, 3-ethyl-1,5-dihydro-5-methylene-
CAS 78210-71-6C7H9NO
3,4-Dimethyl-5-propan-2-ylidenepyrrol-2-one chemical structure, C9H13NO, CAS 37012-27-4
3,4-Dimethyl-5-propan-2-ylidenepyrrol-2-one
CAS 37012-27-4C9H13NO
2-(3-Ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)acetamide chemical structure, C9H10N2O2, CAS 329314-76-3
2-(3-Ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)acetamide
CAS 329314-76-3C9H10N2O2
2-(4-Ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)acetamide chemical structure, C9H10N2O2, CAS 329314-75-2
2-(4-Ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)acetamide
CAS 329314-75-2C9H10N2O2
2-[(2Z)-4-Ethenyl-3-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene]acetamide chemical structure, C9H10N2O2, CAS 1634653-34-1
2-[(2Z)-4-Ethenyl-3-methyl-5-oxo-2,5-dihydro-1H-pyrrol-2-ylidene]acetamide
CAS 1634653-34-1C9H10N2O2
2H-Pyrrol-2-one, 5-ethylidene-1,5-dihydro-4-methyl- chemical structure, C7H9NO, CAS 664336-22-5
2H-Pyrrol-2-one, 5-ethylidene-1,5-dihydro-4-methyl-
CAS 664336-22-5C7H9NO
5-(Bromomethylidene)-4-ethyl-3-methyl-1,5-dihydro-2H-pyrrol-2-one chemical structure, C8H10BrNO, CAS 57097-09-3
5-(Bromomethylidene)-4-ethyl-3-methyl-1,5-dihydro-2H-pyrrol-2-one
CAS 57097-09-3C8H10BrNO
5-Butylidene-1-methylpyrrol-2-one chemical structure, C9H13NO, CAS 87884-58-0
5-Butylidene-1-methylpyrrol-2-one
CAS 87884-58-0C9H13NO
(Z)-5-(2-Hydroxyvinyl)-2H-pyrrol-2-one chemical structure, C6H5NO2, CAS 922179-84-8
(Z)-5-(2-Hydroxyvinyl)-2H-pyrrol-2-one
CAS 922179-84-8C6H5NO2
2-(3-Cyano-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)malononitrile chemical structure, C9H4N4O, CAS 902465-05-8
2-(3-Cyano-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)malononitrile
CAS 902465-05-8C9H4N4O
5MP-Propargyl chemical structure, C8H7NO, CAS 2100286-15-3
5MP-Propargyl
CAS 2100286-15-3C8H7NO
5-Ethylidene-4-hydroxy-1H-pyrrol-2(5H)-one chemical structure, C6H7NO2, CAS 63592-07-4
5-Ethylidene-4-hydroxy-1H-pyrrol-2(5H)-one
CAS 63592-07-4C6H7NO2
(2E)-2-(5-Oxopyrrol-2-ylidene)acetaldehyde chemical structure, C6H5NO2
(2E)-2-(5-Oxopyrrol-2-ylidene)acetaldehyde
C6H5NO2