CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 22 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
17
With full pages
12
Scaffold SMILES

O=C(c1cccs1)N(Cc1ccccc1)C1CCS(=O)(=O)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cccs1)N(Cc1ccccc1)C1CCS(=O)(=O)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

N-(3-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide chemical structure, C16H16ClNO3S2, CAS 620558-88-5
N-(3-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide
CAS 620558-88-5C16H16ClNO3S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-methylbenzyl)thiophene-2-carboxamide chemical structure, C17H19NO3S2, CAS 838876-02-1
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-methylbenzyl)thiophene-2-carboxamide
CAS 838876-02-1C17H19NO3S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethoxybenzyl)thiophene-2-carboxamide chemical structure, C18H21NO4S2, CAS 838880-01-6
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethoxybenzyl)thiophene-2-carboxamide
CAS 838880-01-6C18H21NO4S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-fluorobenzyl)thiophene-2-carboxamide chemical structure, C16H16FNO3S2, CAS 839681-60-6
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-fluorobenzyl)thiophene-2-carboxamide
CAS 839681-60-6C16H16FNO3S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)thiophene-2-carboxamide chemical structure, C17H19NO4S2, CAS 578732-61-3
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)thiophene-2-carboxamide
CAS 578732-61-3C17H19NO4S2
N-(3-Bromobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide chemical structure, C16H16BrNO3S2, CAS 850244-17-6
N-(3-Bromobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide
CAS 850244-17-6C16H16BrNO3S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethylbenzyl)thiophene-2-carboxamide chemical structure, C18H21NO3S2, CAS 620563-12-4
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethylbenzyl)thiophene-2-carboxamide
CAS 620563-12-4C18H21NO3S2
N-(4-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide chemical structure, C16H16ClNO3S2, CAS 620557-21-3
N-(4-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide
CAS 620557-21-3C16H16ClNO3S2
N-[4-(Diethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide chemical structure, C20H26N2O3S2, CAS 848687-51-4
N-[4-(Diethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide
CAS 848687-51-4C20H26N2O3S2
N-[4-(Dimethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide chemical structure, C18H22N2O3S2, CAS 620561-14-0
N-[4-(Dimethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide
CAS 620561-14-0C18H22N2O3S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-[4-(propan-2-yl)benzyl]thiophene-2-carboxamide chemical structure, C19H23NO3S2, CAS 620558-80-7
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-[4-(propan-2-yl)benzyl]thiophene-2-carboxamide
CAS 620558-80-7C19H23NO3S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-propoxybenzyl)thiophene-2-carboxamide chemical structure, C19H23NO4S2, CAS 879945-63-8
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-propoxybenzyl)thiophene-2-carboxamide
CAS 879945-63-8C19H23NO4S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(2-fluorobenzyl)thiophene-2-carboxamide chemical structure, C16H16FNO3S2, CAS 879949-90-3
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(2-fluorobenzyl)thiophene-2-carboxamide
CAS 879949-90-3C16H16FNO3S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(3,4,5-trimethoxybenzyl)thiophene-2-carboxamide chemical structure, C19H23NO6S2, CAS 879966-26-4
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(3,4,5-trimethoxybenzyl)thiophene-2-carboxamide
CAS 879966-26-4C19H23NO6S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(3-methoxybenzyl)thiophene-2-carboxamide chemical structure, C17H19NO4S2, CAS 880392-56-3
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(3-methoxybenzyl)thiophene-2-carboxamide
CAS 880392-56-3C17H19NO4S2
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(3-fluorobenzyl)thiophene-2-carboxamide chemical structure, C16H16FNO3S2, CAS 880785-17-1
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(3-fluorobenzyl)thiophene-2-carboxamide
CAS 880785-17-1C16H16FNO3S2
N-(4-tert-Butylbenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide chemical structure, C20H25NO3S2, CAS 866247-76-9
N-(4-tert-Butylbenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)thiophene-2-carboxamide
CAS 866247-76-9C20H25NO3S2