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Murcko scaffold

Ring system with 3 rings and 22 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
14
With full pages
11
Scaffold SMILES

O=C(c1ccco1)N(Cc1ccccc1)C1CCS(=O)(=O)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccco1)N(Cc1ccccc1)C1CCS(=O)(=O)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N-[4-(Dimethylamino)benzyl]-N-(1,1-dioxidotetrahydro-3-thienyl)-2-furamide chemical structure, C18H22N2O4S, CAS 620561-17-3
N-[4-(Dimethylamino)benzyl]-N-(1,1-dioxidotetrahydro-3-thienyl)-2-furamide
CAS 620561-17-3C18H22N2O4S
N-[4-(Diethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)furan-2-carboxamide chemical structure, C20H26N2O4S, CAS 838894-93-2
N-[4-(Diethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)furan-2-carboxamide
CAS 838894-93-2C20H26N2O4S
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethoxybenzyl)furan-2-carboxamide chemical structure, C18H21NO5S, CAS 847377-48-4
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethoxybenzyl)furan-2-carboxamide
CAS 847377-48-4C18H21NO5S
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)furan-2-carboxamide chemical structure, C17H19NO5S, CAS 620555-93-3
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)furan-2-carboxamide
CAS 620555-93-3C17H19NO5S
N-(1,1-Dioxothiolan-3-yl)-N-[(4-methylphenyl)methyl]furan-2-carboxamide chemical structure, C17H19NO4S, CAS 839681-31-1
N-(1,1-Dioxothiolan-3-yl)-N-[(4-methylphenyl)methyl]furan-2-carboxamide
CAS 839681-31-1C17H19NO4S
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-fluorobenzyl)furan-2-carboxamide chemical structure, C16H16FNO4S, CAS 839682-04-1
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-fluorobenzyl)furan-2-carboxamide
CAS 839682-04-1C16H16FNO4S
N-(3-Chlorobenzyl)-N-(1,1-dioxidotetrahydro-3-thienyl)-2-furamide chemical structure, C16H16ClNO4S, CAS 620558-91-0
N-(3-Chlorobenzyl)-N-(1,1-dioxidotetrahydro-3-thienyl)-2-furamide
CAS 620558-91-0C16H16ClNO4S
N-(3-Bromobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)furan-2-carboxamide chemical structure, C16H16BrNO4S, CAS 850738-85-1
N-(3-Bromobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)furan-2-carboxamide
CAS 850738-85-1C16H16BrNO4S
N-(4-Chlorobenzyl)-N-(1,1-dioxidotetrahydro-3-thienyl)-2-furamide chemical structure, C16H16ClNO4S, CAS 620557-23-5
N-(4-Chlorobenzyl)-N-(1,1-dioxidotetrahydro-3-thienyl)-2-furamide
CAS 620557-23-5C16H16ClNO4S
N-(1,1-Dioxidotetrahydro-3-thienyl)-N-(4-isopropylbenzyl)-2-furamide chemical structure, C19H23NO4S, CAS 573932-77-1
N-(1,1-Dioxidotetrahydro-3-thienyl)-N-(4-isopropylbenzyl)-2-furamide
CAS 573932-77-1C19H23NO4S
N-(1,1-Dioxidotetrahydro-3-thienyl)-N-(4-ethylbenzyl)-2-furamide chemical structure, C18H21NO4S, CAS 620563-17-9
N-(1,1-Dioxidotetrahydro-3-thienyl)-N-(4-ethylbenzyl)-2-furamide
CAS 620563-17-9C18H21NO4S
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(2-fluorobenzyl)furan-2-carboxamide chemical structure, C16H16FNO4S, CAS 879949-76-5
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(2-fluorobenzyl)furan-2-carboxamide
CAS 879949-76-5C16H16FNO4S
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(3-fluorobenzyl)furan-2-carboxamide chemical structure, C16H16FNO4S, CAS 880785-19-3
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(3-fluorobenzyl)furan-2-carboxamide
CAS 880785-19-3C16H16FNO4S
N-(4-tert-Butylbenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)furan-2-carboxamide chemical structure, C20H25NO4S, CAS 866247-77-0
N-(4-tert-Butylbenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)furan-2-carboxamide
CAS 866247-77-0C20H25NO4S