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Murcko scaffold

Ring system with 4 rings and 27 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
7
With full pages
1
Scaffold SMILES

O=c1[nH]c2cc(NS(=O)(=O)c3ccccc3)c(Oc3ccccc3)cc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2cc(NS(=O)(=O)c3ccccc3)c(Oc3ccccc3)cc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

4-Ethyl-N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzene-1-sulfonamide chemical structure, C24H25N3O5S, CAS 1243049-38-8
4-Ethyl-N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzene-1-sulfonamide
CAS 1243049-38-8C24H25N3O5S
3,4-Dimethoxy-N-[6-(4-Methoxyphenoxy)-1,3-Dimethyl-2-Oxo-2,3-Dihydro-1H-Benzimidazol-5-Yl]benzenesulfonamide chemical structure, C24H25N3O7S, CAS 1242907-48-7
3,4-Dimethoxy-N-[6-(4-Methoxyphenoxy)-1,3-Dimethyl-2-Oxo-2,3-Dihydro-1H-Benzimidazol-5-Yl]benzenesulfonamide
CAS 1242907-48-7C24H25N3O7S
Iacs-9571 chemical structure, C32H42N4O8S, CAS 1800477-30-8
Iacs-9571
CAS 1800477-30-8C32H42N4O8S
IACS-9571 Trifluoroacetate chemical structure, C34H43F3N4O10S, CAS 1883598-69-3
IACS-9571 Trifluoroacetate
CAS 1883598-69-3C34H43F3N4O10S
IACS-7e chemical structure, C26H29N3O7S, CAS 1800477-13-7
IACS-7e
CAS 1800477-13-7C26H29N3O7S
3-(N-(1,3-Dimethyl-2-oxo-6-(3-propoxyphenoxy)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)sulfamoyl)benzoic acid chemical structure, C25H25N3O7S, CAS 1884199-58-9
3-(N-(1,3-Dimethyl-2-oxo-6-(3-propoxyphenoxy)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)sulfamoyl)benzoic acid
CAS 1884199-58-9C25H25N3O7S
IACS-9571 Hydrochloride chemical structure, C32H43ClN4O8S, CAS 2319611-93-1
IACS-9571 Hydrochloride
CAS 2319611-93-1C32H43ClN4O8S