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Murcko scaffold

Ring system with 4 rings and 25 atoms

17 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
17
With full pages
1
Scaffold SMILES

O=c1c2sccc2nc(SCc2ccccc2)n1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2sccc2nc(SCc2ccccc2)n1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

Spl-334 chemical structure, C22H15N3O3S2, CAS 688347-51-5
Spl-334
CAS 688347-51-5C22H15N3O3S2
2-((2-Chlorobenzyl)thio)-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C20H14ClFN2OS2, CAS 440326-40-9
2-((2-Chlorobenzyl)thio)-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 440326-40-9C20H14ClFN2OS2
3-(2-Fluorobenzyl)-2-((2-fluorobenzyl)thio)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C20H14F2N2OS2, CAS 440326-53-4
3-(2-Fluorobenzyl)-2-((2-fluorobenzyl)thio)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 440326-53-4C20H14F2N2OS2
3-(2-Fluorobenzyl)-2-[(2-methylbenzyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C21H17FN2OS2, CAS 1326907-43-0
3-(2-Fluorobenzyl)-2-[(2-methylbenzyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326907-43-0C21H17FN2OS2
3-(2-Fluorobenzyl)-2-[(3-methylbenzyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C21H17FN2OS2, CAS 1326926-74-2
3-(2-Fluorobenzyl)-2-[(3-methylbenzyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326926-74-2C21H17FN2OS2
3-(2-Fluorobenzyl)-2-[(4-methylbenzyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C21H17FN2OS2, CAS 1326888-47-4
3-(2-Fluorobenzyl)-2-[(4-methylbenzyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326888-47-4C21H17FN2OS2
2-[(2,5-Dimethylbenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C22H19FN2OS2, CAS 1326853-32-0
2-[(2,5-Dimethylbenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326853-32-0C22H19FN2OS2
2-[(3,4-Dimethylbenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C22H19FN2OS2, CAS 1326914-63-9
2-[(3,4-Dimethylbenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326914-63-9C22H19FN2OS2
2-[(4-tert-Butylbenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C24H23FN2OS2, CAS 1326907-60-1
2-[(4-tert-Butylbenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326907-60-1C24H23FN2OS2
2-[(4-Ethenylbenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C22H17FN2OS2, CAS 2117746-40-2
2-[(4-Ethenylbenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 2117746-40-2C22H17FN2OS2
3-(2-Fluorobenzyl)-2-[(3-methoxybenzyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C21H17FN2O2S2, CAS 1326840-82-7
3-(2-Fluorobenzyl)-2-[(3-methoxybenzyl)sulfanyl]thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326840-82-7C21H17FN2O2S2
3-({[3-(2-Fluorobenzyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}methyl)benzonitrile chemical structure, C21H14FN3OS2, CAS 1326932-66-4
3-({[3-(2-Fluorobenzyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}methyl)benzonitrile
CAS 1326932-66-4C21H14FN3OS2
2-[(3,5-Difluorobenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C20H13F3N2OS2, CAS 1326870-40-9
2-[(3,5-Difluorobenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326870-40-9C20H13F3N2OS2
2-[(2-Chloro-6-fluorobenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C20H13ClF2N2OS2, CAS 1326916-16-8
2-[(2-Chloro-6-fluorobenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326916-16-8C20H13ClF2N2OS2
3-(2-Fluorobenzyl)-2-{[3-(trifluoromethyl)benzyl]sulfanyl}thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C21H14F4N2OS2, CAS 1326820-43-2
3-(2-Fluorobenzyl)-2-{[3-(trifluoromethyl)benzyl]sulfanyl}thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326820-43-2C21H14F4N2OS2
2-[(3,4-Difluorobenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C20H13F3N2OS2, CAS 1326827-80-8
2-[(3,4-Difluorobenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326827-80-8C20H13F3N2OS2
2-[(2,4-Difluorobenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C20H13F3N2OS2, CAS 1326861-52-2
2-[(2,4-Difluorobenzyl)sulfanyl]-3-(2-fluorobenzyl)thieno[3,2-d]pyrimidin-4(3H)-one
CAS 1326861-52-2C20H13F3N2OS2