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Murcko scaffold

N-Benzylpyrazin-2-amine scaffold

93 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
93
With full pages
8
Scaffold SMILES

c1ccc(CNc2cnccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the n-Benzylpyrazin-2-amine page
Murcko scaffold c1ccc(CNc2cnccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 93 chemicals

5-(N-Ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride chemical structure, C16H19ClN8O4, CAS 123844-08-6
5-(N-Ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride
CAS 123844-08-6C16H19ClN8O4
n-Benzylpyrazin-2-amine chemical structure, C11H11N3, CAS 7375-45-3
n-Benzylpyrazin-2-amine
CAS 7375-45-3C11H11N3
Methyl 3-amino-5-(benzylamino)-6-chloropyrazine-2-carboxylate chemical structure, C13H13ClN4O2, CAS 1154-82-1
Methyl 3-amino-5-(benzylamino)-6-chloropyrazine-2-carboxylate
CAS 1154-82-1C13H13ClN4O2
N-(4-Methylbenzyl)-2-pyrazinamine chemical structure, C12H13N3, CAS 280117-03-5
N-(4-Methylbenzyl)-2-pyrazinamine
CAS 280117-03-5C12H13N3
N-(4-Chlorobenzyl)-N-(2-pyrazinyl)acetamide chemical structure, C13H12ClN3O, CAS 78675-55-5
N-(4-Chlorobenzyl)-N-(2-pyrazinyl)acetamide
CAS 78675-55-5C13H12ClN3O
N-[(4-Fluorophenyl)methyl]pyrazin-2-amine chemical structure, C11H10FN3, CAS 866151-20-4
N-[(4-Fluorophenyl)methyl]pyrazin-2-amine
CAS 866151-20-4C11H10FN3
N-(4-Chlorobenzyl)-2,2,2-trifluoro-N-(2-pyrazinyl)acetamide chemical structure, C13H9ClF3N3O, CAS 866042-29-7
N-(4-Chlorobenzyl)-2,2,2-trifluoro-N-(2-pyrazinyl)acetamide
CAS 866042-29-7C13H9ClF3N3O
N-[(2,4-Dichlorophenyl)methyl]pyrazin-2-amine chemical structure, C11H9Cl2N3, CAS 866151-19-1
N-[(2,4-Dichlorophenyl)methyl]pyrazin-2-amine
CAS 866151-19-1C11H9Cl2N3
N-[(3,4-Dichlorophenyl)methyl]pyrazin-2-amine chemical structure, C11H9Cl2N3, CAS 866151-70-4
N-[(3,4-Dichlorophenyl)methyl]pyrazin-2-amine
CAS 866151-70-4C11H9Cl2N3
N-[(4-Chlorophenyl)methyl]pyrazin-2-amine chemical structure, C11H10ClN3, CAS 78675-97-5
N-[(4-Chlorophenyl)methyl]pyrazin-2-amine
CAS 78675-97-5C11H10ClN3
4-[(2-Pyrazinylamino)methyl]benzenecarbonitrile chemical structure, C12H10N4, CAS 866042-52-6
4-[(2-Pyrazinylamino)methyl]benzenecarbonitrile
CAS 866042-52-6C12H10N4
N-(4-Chlorobenzyl)-2,2-dimethyl-N-(2-pyrazinyl)propanamide chemical structure, C16H18ClN3O, CAS 78675-25-9
N-(4-Chlorobenzyl)-2,2-dimethyl-N-(2-pyrazinyl)propanamide
CAS 78675-25-9C16H18ClN3O
2,2,2-Trifluoro-N-(4-methylbenzyl)-N-(2-pyrazinyl)acetamide chemical structure, C14H12F3N3O, CAS 866042-28-6
2,2,2-Trifluoro-N-(4-methylbenzyl)-N-(2-pyrazinyl)acetamide
CAS 866042-28-6C14H12F3N3O
3-(Benzylamino)pyrazine-2-carbonitrile chemical structure, C12H10N4, CAS 146779-37-5
3-(Benzylamino)pyrazine-2-carbonitrile
CAS 146779-37-5C12H10N4
N-(4-Bromobenzyl)pyrazin-2-amine chemical structure, C11H10BrN3, CAS 280117-02-4
N-(4-Bromobenzyl)pyrazin-2-amine
CAS 280117-02-4C11H10BrN3
2-(3-Fluorobenzylamino)-6-chloropyrazine chemical structure, C11H9ClFN3, CAS 874143-73-4
2-(3-Fluorobenzylamino)-6-chloropyrazine
CAS 874143-73-4C11H9ClFN3
N-Benzyl-6-chloropyrazin-2-amine chemical structure, C11H10ClN3, CAS 426829-61-0
N-Benzyl-6-chloropyrazin-2-amine
CAS 426829-61-0C11H10ClN3
3-(Benzylamino)pyrazine-2-carboxamide chemical structure, C12H12N4O, CAS 64344-97-4
3-(Benzylamino)pyrazine-2-carboxamide
CAS 64344-97-4C12H12N4O
3-(Benzylamino)-5,6-dimethylpyrazine-2-carboxamide chemical structure, C14H16N4O, CAS 64344-94-1
3-(Benzylamino)-5,6-dimethylpyrazine-2-carboxamide
CAS 64344-94-1C14H16N4O
N-[(2,4-Dichlorophenyl)methyl]-2,2-dimethyl-N-2-pyrazinylpropanamide chemical structure, C16H17Cl2N3O, CAS 84401-20-7
N-[(2,4-Dichlorophenyl)methyl]-2,2-dimethyl-N-2-pyrazinylpropanamide
CAS 84401-20-7C16H17Cl2N3O
N-Benzyl-6-chloro-N-methylpyrazin-2-amine chemical structure, C12H12ClN3, CAS 629657-99-4
N-Benzyl-6-chloro-N-methylpyrazin-2-amine
CAS 629657-99-4C12H12ClN3
N-(4-Methoxybenzyl)-6-chloropyrazin-2-amine chemical structure, C12H12ClN3O, CAS 355836-31-6
N-(4-Methoxybenzyl)-6-chloropyrazin-2-amine
CAS 355836-31-6C12H12ClN3O
3-[(6-Chloro-pyrazin-2-ylamino)-methyl]-benzonitrile chemical structure, C12H9ClN4, CAS 479685-47-7
3-[(6-Chloro-pyrazin-2-ylamino)-methyl]-benzonitrile
CAS 479685-47-7C12H9ClN4
(3-Chloro-benzyl)-(6-chloro-pyrazin-2-yl)-amine chemical structure, C11H9Cl2N3, CAS 479684-59-8
(3-Chloro-benzyl)-(6-chloro-pyrazin-2-yl)-amine
CAS 479684-59-8C11H9Cl2N3