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Murcko scaffold

Ring system with 4 rings and 21 atoms

21 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
21
With full pages
3
Scaffold SMILES

O=C1C(=Cc2ccccc2)CCc2c1[nH]c1ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=Cc2ccccc2)CCc2c1[nH]c1ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

(2E)-2-[(2-Chlorophenyl)methylidene]-6-methyl-4,9-dihydro-3H-carbazol-1-one chemical structure, C20H16ClNO, CAS 352549-34-9
(2E)-2-[(2-Chlorophenyl)methylidene]-6-methyl-4,9-dihydro-3H-carbazol-1-one
CAS 352549-34-9C20H16ClNO
2-Benzylidene-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one chemical structure, C20H17NO, CAS 1164540-75-3
2-Benzylidene-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one
CAS 1164540-75-3C20H17NO
2-{(Z)-[2-(Trifluoromethyl)phenyl]methylidene}-4,9-dihydro-1H-carbazol-1(3H)-one chemical structure, C20H14F3NO
2-{(Z)-[2-(Trifluoromethyl)phenyl]methylidene}-4,9-dihydro-1H-carbazol-1(3H)-one
C20H14F3NO
2-[(4-Chlorophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C19H14ClNO
2-[(4-Chlorophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one
C19H14ClNO
2-[(4-Methylphenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C20H17NO, CAS 866149-13-5
2-[(4-Methylphenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one
CAS 866149-13-5C20H17NO
(2E)-2-[(2-Methoxyphenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C20H17NO2, CAS 866138-43-4
(2E)-2-[(2-Methoxyphenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one
CAS 866138-43-4C20H17NO2
(2E)-2-[[2-(Trifluoromethyl)phenyl]methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C20H14F3NO
(2E)-2-[[2-(Trifluoromethyl)phenyl]methylidene]-4,9-dihydro-3H-carbazol-1-one
C20H14F3NO
(2Z)-2-[(4-Chlorophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C19H14ClNO, CAS 866149-10-2
(2Z)-2-[(4-Chlorophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one
CAS 866149-10-2C19H14ClNO
(2E)-2-[(4-Methylphenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C20H17NO
(2E)-2-[(4-Methylphenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one
C20H17NO
(2E)-2-[(4-Methoxyphenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C20H17NO2, CAS 1147118-58-8
(2E)-2-[(4-Methoxyphenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one
CAS 1147118-58-8C20H17NO2
(2E)-2-[(2-Chlorophenyl)methylidene]-2,3,4,9-tetrahydro-1H-carbazol-1-one chemical structure, C19H14ClNO, CAS 866138-45-6
(2E)-2-[(2-Chlorophenyl)methylidene]-2,3,4,9-tetrahydro-1H-carbazol-1-one
CAS 866138-45-6C19H14ClNO
(2E)-2-[(3,4-Dichlorophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C19H13Cl2NO, CAS 866149-08-8
(2E)-2-[(3,4-Dichlorophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one
CAS 866149-08-8C19H13Cl2NO
(2E)-2-[(3-Nitrophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C19H14N2O3, CAS 866138-42-3
(2E)-2-[(3-Nitrophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one
CAS 866138-42-3C19H14N2O3
(2E)-2-[(3-Fluorophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one chemical structure, C19H14FNO, CAS 866138-41-2
(2E)-2-[(3-Fluorophenyl)methylidene]-4,9-dihydro-3H-carbazol-1-one
CAS 866138-41-2C19H14FNO
2-[(Z)-(4-Methylphenyl)methylidene]-4,9-dihydro-1H-carbazol-1(3H)-one chemical structure, C20H17NO, CAS 1164469-52-6
2-[(Z)-(4-Methylphenyl)methylidene]-4,9-dihydro-1H-carbazol-1(3H)-one
CAS 1164469-52-6C20H17NO
2-[(Z)-Phenylmethylidene]-4,9-dihydro-1H-carbazol-1(3H)-one chemical structure, C19H15NO, CAS 1164562-06-4
2-[(Z)-Phenylmethylidene]-4,9-dihydro-1H-carbazol-1(3H)-one
CAS 1164562-06-4C19H15NO
(2Z)-2-{[2-(Trifluoromethyl)phenyl]methylidene}-2,3,4,9-tetrahydro-1H-carbazol-1-one chemical structure, C20H14F3NO, CAS 866149-09-9
(2Z)-2-{[2-(Trifluoromethyl)phenyl]methylidene}-2,3,4,9-tetrahydro-1H-carbazol-1-one
CAS 866149-09-9C20H14F3NO
(2Z)-2-[(2-Fluorophenyl)methylidene]-2,3,4,9-tetrahydro-1H-carbazol-1-one chemical structure, C19H14FNO, CAS 1351509-64-2
(2Z)-2-[(2-Fluorophenyl)methylidene]-2,3,4,9-tetrahydro-1H-carbazol-1-one
CAS 1351509-64-2C19H14FNO
2-[(Z)-(4-Chlorophenyl)methylidene]-4,9-dihydro-1H-carbazol-1(3H)-one chemical structure, C19H14ClNO
2-[(Z)-(4-Chlorophenyl)methylidene]-4,9-dihydro-1H-carbazol-1(3H)-one
C19H14ClNO
2-Benzylidene-7-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one chemical structure, C20H17NO, CAS 344930-76-3
2-Benzylidene-7-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one
CAS 344930-76-3C20H17NO
2-Benzylidene-8-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one chemical structure, C20H17NO, CAS 344930-75-2
2-Benzylidene-8-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one
CAS 344930-75-2C20H17NO