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Murcko scaffold

Ring system with 4 rings and 20 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
8
With full pages
2
Scaffold SMILES

c1ccc(CN2CCc3c([nH]c4ccccc34)C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CN2CCc3c([nH]c4ccccc34)C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-[(3-Methylphenyl)methyl]-1,3,4,9-tetrahydropyrido[3,4-b]indole chemical structure, C19H20N2, CAS 376379-24-7
2-[(3-Methylphenyl)methyl]-1,3,4,9-tetrahydropyrido[3,4-b]indole
CAS 376379-24-7C19H20N2
1H-Pyrido(3,4-b)indole, 2,3,4,9-tetrahydro-1-((3,4-dimethoxyphenyl)methyl)- chemical structure, C20H22N2O2, CAS 68861-49-4
1H-Pyrido(3,4-b)indole, 2,3,4,9-tetrahydro-1-((3,4-dimethoxyphenyl)methyl)-
CAS 68861-49-4C20H22N2O2
2-[(2-Fluorophenyl)methyl]-1,3,4,9-tetrahydropyrido[3,4-b]indole chemical structure, C18H17FN2, CAS 5284-72-0
2-[(2-Fluorophenyl)methyl]-1,3,4,9-tetrahydropyrido[3,4-b]indole
CAS 5284-72-0C18H17FN2
2-(4-Methoxy-3-methylbenzyl)-2,3,4,9-tetrahydro-1H-beta-carboline chemical structure, C20H22N2O, CAS 5285-15-4
2-(4-Methoxy-3-methylbenzyl)-2,3,4,9-tetrahydro-1H-beta-carboline
CAS 5285-15-4C20H22N2O
2-[(4-Propan-2-ylphenyl)methyl]-1,3,4,9-tetrahydropyrido[3,4-b]indole chemical structure, C21H24N2, CAS 4505-80-0
2-[(4-Propan-2-ylphenyl)methyl]-1,3,4,9-tetrahydropyrido[3,4-b]indole
CAS 4505-80-0C21H24N2
Methyl 2,3,4,9-tetrahydro-9-methyl-2-(phenylmethyl)-1H-pyrido[3,4-b]indole-1-acetate chemical structure, C22H24N2O2, CAS 169120-74-5
Methyl 2,3,4,9-tetrahydro-9-methyl-2-(phenylmethyl)-1H-pyrido[3,4-b]indole-1-acetate
CAS 169120-74-5C22H24N2O2
2-Benzyl-9-methyl-2,3,4,9-tetrahydro-1H-beta-carboline chemical structure, C19H20N2, CAS 65967-54-6
2-Benzyl-9-methyl-2,3,4,9-tetrahydro-1H-beta-carboline
CAS 65967-54-6C19H20N2
Callophycin A chemical structure, C19H18N2O3, CAS 1345674-93-2
Callophycin A
CAS 1345674-93-2C19H18N2O3