Murcko scaffold
5,6,7,8-Tetrahydroindolizin-8-one scaffold
14 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 14
- With full pages
- 2
Scaffold SMILES
O=C1CCCn2cccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 14 of 14 chemicals
Ethyl 8-oxo-5,6,7,8-tetrahydroindolizine-5-carboxylate
CAS 259683-86-8C11H13NO3
Methyl 8-oxo-6,7-dihydro-5H-indolizine-5-carboxylate
CAS 318247-33-5C10H11NO3
5,6,7,8-Tetrahydroindolizin-8-one
CAS 54906-44-4C8H9NO
5-Methyl-6,7-dihydroindolizin-8(5H)-one
CAS 864426-31-3C9H11NO
3-(Hydroxymethyl)-6,7-dihydroindolizin-8(5H)-one
CAS 400715-63-1C9H11NO2
3-Indolizinecarboxaldehyde, 5,6,7,8-tetrahydro-8-oxo-
CAS 400715-60-8C9H9NO2
Kinganone
CAS 744198-33-2C13H19NO2
3-Bromo-6,7-dihydroindolizin-8(5H)-one
CAS 1199971-55-5C8H8BrNO
8-Oxo-5,6,7,8-tetrahydroindolizine-5-carboxylic acid
CAS 1218197-94-4C9H9NO3
2-Iodo-6,7-dihydroindolizin-8(5H)-one
CAS 1416221-39-0C8H8INO
2-Iodo-7,7-dimethyl-6,7-dihydroindolizin-8(5H)-one
CAS 1416221-72-1C10H12INO
3-Bromo-7,7-difluoro-1-(trifluoromethyl)-6,7-dihydroindolizin-8(5H)-one
CAS 2755402-06-1C9H5BrF5NO
3-Bromo-7-fluoro-1-(trifluoromethyl)-6,7-dihydroindolizin-8(5H)-one
CAS 2755402-05-0C9H6BrF4NO
cis-Procuramine
CAS 2763578-21-6C10H13NO2