CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 19 atoms

69 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
69
With full pages
7
Scaffold SMILES

O=c1ccn(C2CC2)c2cc(N3CCCC3)ccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(C2CC2)c2cc(N3CCCC3)ccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 69 chemicals

3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, hydrochloride (1:1) chemical structure, C17H18Cl2FN3O3, CAS 105956-99-8
3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, hydrochloride (1:1)
CAS 105956-99-8C17H18Cl2FN3O3
Clinafloxacin chemical structure, C17H17ClFN3O3, CAS 105956-97-6
Clinafloxacin
CAS 105956-97-6C17H17ClFN3O3
Premafloxacin chemical structure, C21H26FN3O4, CAS 143383-65-7
Premafloxacin
CAS 143383-65-7C21H26FN3O4
PD 117588 chemical structure, C20H23F2N3O3, CAS 99734-97-1
PD 117588
CAS 99734-97-1C20H23F2N3O3
7-(3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid chemical structure, C17H17F2N3O3, CAS 99734-98-2
7-(3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS 99734-98-2C17H17F2N3O3
3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo- chemical structure, C18H20FN3O4, CAS 112811-60-6
3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-
CAS 112811-60-6C18H20FN3O4
PD 124816 chemical structure, C17H18F2N4O3, CAS 112654-98-5
PD 124816
CAS 112654-98-5C17H18F2N4O3
7-(3-(1-Aminoethyl)-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-3-quinolinecarboxylic acid chemical structure, C20H21F4N3O3, CAS 118829-01-9
7-(3-(1-Aminoethyl)-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-3-quinolinecarboxylic acid
CAS 118829-01-9C20H21F4N3O3
7-(3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-3-quinolinecarboxylic acid chemical structure, C18H17F4N3O3, CAS 118829-10-0
7-(3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-3-quinolinecarboxylic acid
CAS 118829-10-0C18H17F4N3O3
7-((3S)-3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid chemical structure, C17H17F2N3O3, CAS 133298-78-9
7-((3S)-3-Amino-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS 133298-78-9C17H17F2N3O3
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]- chemical structure, C22H25F4N3O3, CAS 143382-87-0
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[3-[1-(ethylamino)ethyl]-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-8-(trifluoromethyl)-, [R-(R*,R*)]-
CAS 143382-87-0C22H25F4N3O3
(S-(R,S))-1-Cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid chemical structure, C22H28FN3O4, CAS 143382-96-1
(S-(R,S))-1-Cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
CAS 143382-96-1C22H28FN3O4
(R-(R,R))-1-Cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid chemical structure, C22H28FN3O4, CAS 143382-95-0
(R-(R,R))-1-Cyclopropyl-7-(3-(1-(ethylamino)ethyl)-1-pyrrolidinyl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
CAS 143382-95-0C22H28FN3O4
(S-(R,S))-1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(3-(1-(methylamino)ethyl)-1-pyrrolidinyl)-4-oxo-8-(trifluoromethyl)-3-quinolinecarboxylic acid chemical structure, C21H23F4N3O3, CAS 143383-67-9
(S-(R,S))-1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(3-(1-(methylamino)ethyl)-1-pyrrolidinyl)-4-oxo-8-(trifluoromethyl)-3-quinolinecarboxylic acid
CAS 143383-67-9C21H23F4N3O3
1-Cyclopropyl-6-fluoro-1, 4-dihydro-8-methoxy-7-(3-methyl-3-((methylamino)methyl)-1-pyrrolidinyl)-4-oxo-3-quinolinecarboxylic acid chemical structure, C21H26FN3O4, CAS 144633-97-6
1-Cyclopropyl-6-fluoro-1, 4-dihydro-8-methoxy-7-(3-methyl-3-((methylamino)methyl)-1-pyrrolidinyl)-4-oxo-3-quinolinecarboxylic acid
CAS 144633-97-6C21H26FN3O4
3-Quinolinecarboxylic acid, 1,4-dihydro-5-amino-1-cyclopropyl-6,8-difluoro-7-(3-methyl-3-((methylamino)methyl)-1-pyrrolidinyl)-4-oxo- chemical structure, C20H24F2N4O3, CAS 146981-03-5
3-Quinolinecarboxylic acid, 1,4-dihydro-5-amino-1-cyclopropyl-6,8-difluoro-7-(3-methyl-3-((methylamino)methyl)-1-pyrrolidinyl)-4-oxo-
CAS 146981-03-5C20H24F2N4O3
3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-, (S)- chemical structure, C18H20FN3O4, CAS 146981-06-8
3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-, (S)-
CAS 146981-06-8C18H20FN3O4
5-Amino-7-(3-(aminomethyl)-3-methyl-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid chemical structure, C20H25FN4O4, CAS 146981-08-0
5-Amino-7-(3-(aminomethyl)-3-methyl-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
CAS 146981-08-0C20H25FN4O4
3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-(1-amino-1-methylethyl)-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-, (R)- chemical structure, C20H23ClFN3O3, CAS 143158-17-2
3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-(1-amino-1-methylethyl)-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-, (R)-
CAS 143158-17-2C20H23ClFN3O3
3-Quinolinecarboxylic acid, 1,4-dihydro-5-amino-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-, (S)- chemical structure, C18H21FN4O4, CAS 146981-09-1
3-Quinolinecarboxylic acid, 1,4-dihydro-5-amino-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-, (S)-
CAS 146981-09-1C18H21FN4O4
3-Quinolinecarboxylic acid, 7-(3-((ethylamino)methyl)-1-pyrrolidinyl)-6,8-difluoro-1,4-dihydro-1-(1-methylcyclopropyl)-4-oxo- chemical structure, C21H25F2N3O3, CAS 99735-15-6
3-Quinolinecarboxylic acid, 7-(3-((ethylamino)methyl)-1-pyrrolidinyl)-6,8-difluoro-1,4-dihydro-1-(1-methylcyclopropyl)-4-oxo-
CAS 99735-15-6C21H25F2N3O3
3-Quinolinecarboxylic acid, 8-bromo-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-((methylamino)methyl)-1-pyrrolidinyl)-4-oxo- chemical structure, C19H21BrFN3O3, CAS 104456-05-5
3-Quinolinecarboxylic acid, 8-bromo-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-((methylamino)methyl)-1-pyrrolidinyl)-4-oxo-
CAS 104456-05-5C19H21BrFN3O3
1-Cyclopropyl-6-fluoro-8-methoxy-7-{3-[(methylamino)methyl]pyrrolidin-1-yl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chemical structure, C20H24FN3O4, CAS 112811-75-3
1-Cyclopropyl-6-fluoro-8-methoxy-7-{3-[(methylamino)methyl]pyrrolidin-1-yl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS 112811-75-3C20H24FN3O4
1-Cyclopropyl-8-ethoxy-6-fluoro-7-{3-[(methylamino)methyl]pyrrolidin-1-yl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chemical structure, C21H26FN3O4, CAS 182868-80-0
1-Cyclopropyl-8-ethoxy-6-fluoro-7-{3-[(methylamino)methyl]pyrrolidin-1-yl}-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS 182868-80-0C21H26FN3O4