Murcko scaffold
Ring system with 5 rings and 29 atoms
8 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 29
- Chemicals
- 8
- With full pages
- 3
Scaffold SMILES
O=C(Nc1ccccn1)c1ccc(-c2nc(C3CCCN3)n3ccncc23)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
![(S)-4-(8-Amino-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide chemical structure, C22H21N7O, CAS 1420478-90-5](/s/RWBYECCAYSUTDK-INIZCTEOSA-N.svg)
(S)-4-(8-Amino-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
CAS 1420478-90-5C22H21N7O
Acalabrutinib
CAS 1420477-60-6C26H23N7O2
Acalabrutinib enantiomer
CAS 1952316-43-6C26H23N7O2
Acalabrutinib maleate
CAS 2242394-65-4C30H27N7O6
Acalabrutinib-D4
CAS 2699608-18-7C26H23N7O2
Acalabrutinib dihydrate
CAS 2648852-74-6C26H27N7O4
Acalabrutinib maleate monohydrate
CAS 2641500-53-8C30H29N7O7
![tert-Butyl (S)-(1-(4-(pyridin-2-ylcarbamoyl)phenyl)-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-8-yl)carbamate chemical structure, C27H29N7O3, CAS 2170801-91-7](/s/ZZGZHXUEFBPRJI-IBGZPJMESA-N.svg)
tert-Butyl (S)-(1-(4-(pyridin-2-ylcarbamoyl)phenyl)-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-8-yl)carbamate
CAS 2170801-91-7C27H29N7O3