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Murcko scaffold

N-[3-(1-Piperazinyl)phenyl]benzenemethanamine scaffold

42 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
42
With full pages
14
Scaffold SMILES

c1ccc(CNc2cccc(N3CCNCC3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[3-(1-Piperazinyl)phenyl]benzenemethanamine page
Murcko scaffold c1ccc(CNc2cccc(N3CCNCC3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

N-Benzyl-2-nitro-5-piperazin-1-ylaniline chemical structure, C17H20N4O2, CAS 346704-07-2
N-Benzyl-2-nitro-5-piperazin-1-ylaniline
CAS 346704-07-2C17H20N4O2
N-Benzyl-5-(4-methylpiperazin-1-yl)-2-nitroaniline chemical structure, C18H22N4O2, CAS 330634-15-6
N-Benzyl-5-(4-methylpiperazin-1-yl)-2-nitroaniline
CAS 330634-15-6C18H22N4O2
2-[4-[3-(Benzylamino)-4-nitrophenyl]piperazin-1-yl]ethanol chemical structure, C19H24N4O3, CAS 330634-16-7
2-[4-[3-(Benzylamino)-4-nitrophenyl]piperazin-1-yl]ethanol
CAS 330634-16-7C19H24N4O3
N-Benzyl-5-(3-methylpiperazin-1-yl)-2-nitroaniline chemical structure, C18H22N4O2, CAS 330177-55-4
N-Benzyl-5-(3-methylpiperazin-1-yl)-2-nitroaniline
CAS 330177-55-4C18H22N4O2
2-[4-[3-[(4-Chlorophenyl)methylamino]-4-nitrophenyl]piperazin-1-yl]ethanol chemical structure, C19H23ClN4O3, CAS 330177-37-2
2-[4-[3-[(4-Chlorophenyl)methylamino]-4-nitrophenyl]piperazin-1-yl]ethanol
CAS 330177-37-2C19H23ClN4O3
5-(4-Methylsulfonylpiperazin-1-yl)-2-nitro-N-[(4-propan-2-ylphenyl)methyl]aniline chemical structure, C21H28N4O4S, CAS 347353-81-5
5-(4-Methylsulfonylpiperazin-1-yl)-2-nitro-N-[(4-propan-2-ylphenyl)methyl]aniline
CAS 347353-81-5C21H28N4O4S
N-[1-(4-Bromophenyl)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline chemical structure, C19H23BrN4O2, CAS 347354-29-4
N-[1-(4-Bromophenyl)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline
CAS 347354-29-4C19H23BrN4O2
2-[4-[3-[1-(4-Bromophenyl)ethylamino]-4-nitrophenyl]piperazin-1-yl]ethanol chemical structure, C20H25BrN4O3, CAS 347353-87-1
2-[4-[3-[1-(4-Bromophenyl)ethylamino]-4-nitrophenyl]piperazin-1-yl]ethanol
CAS 347353-87-1C20H25BrN4O3
N-[(4-Chlorophenyl)methyl]-5-(4-methylsulfonylpiperazin-1-yl)-2-nitroaniline chemical structure, C18H21ClN4O4S, CAS 347356-07-4
N-[(4-Chlorophenyl)methyl]-5-(4-methylsulfonylpiperazin-1-yl)-2-nitroaniline
CAS 347356-07-4C18H21ClN4O4S
5-(4-Methylsulfonylpiperazin-1-yl)-2-nitro-N-(1-phenylethyl)aniline chemical structure, C19H24N4O4S, CAS 347310-97-8
5-(4-Methylsulfonylpiperazin-1-yl)-2-nitro-N-(1-phenylethyl)aniline
CAS 347310-97-8C19H24N4O4S
1-[4-[3-(Benzylamino)-4-nitrophenyl]piperazin-1-yl]ethanone chemical structure, C19H22N4O3, CAS 347356-35-8
1-[4-[3-(Benzylamino)-4-nitrophenyl]piperazin-1-yl]ethanone
CAS 347356-35-8C19H22N4O3
1-[4-[3-[(4-Chlorophenyl)methylamino]-4-nitrophenyl]piperazin-1-yl]ethanone chemical structure, C19H21ClN4O3, CAS 347356-37-0
1-[4-[3-[(4-Chlorophenyl)methylamino]-4-nitrophenyl]piperazin-1-yl]ethanone
CAS 347356-37-0C19H21ClN4O3
1-[4-[4-Nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]ethanone chemical structure, C20H24N4O3, CAS 347313-80-8
1-[4-[4-Nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]ethanone
CAS 347313-80-8C20H24N4O3
2-[4-[4-Nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]ethanol chemical structure, C20H26N4O3, CAS 430457-19-5
2-[4-[4-Nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]ethanol
CAS 430457-19-5C20H26N4O3
5-(4-Methylpiperazin-1-yl)-2-nitro-N-(1-phenylethyl)aniline chemical structure, C19H24N4O2, CAS 430458-53-0
5-(4-Methylpiperazin-1-yl)-2-nitro-N-(1-phenylethyl)aniline
CAS 430458-53-0C19H24N4O2
5-(4-Ethylsulfonylpiperazin-1-yl)-2-nitro-N-(1-phenylethyl)aniline chemical structure, C20H26N4O4S, CAS 430446-82-5
5-(4-Ethylsulfonylpiperazin-1-yl)-2-nitro-N-(1-phenylethyl)aniline
CAS 430446-82-5C20H26N4O4S
N-Benzyl-5-(4-ethylsulfonylpiperazin-1-yl)-2-nitroaniline chemical structure, C19H24N4O4S, CAS 430449-03-9
N-Benzyl-5-(4-ethylsulfonylpiperazin-1-yl)-2-nitroaniline
CAS 430449-03-9C19H24N4O4S
1-[4-[3-(Benzylamino)-4-nitrophenyl]piperazin-1-yl]propan-1-one chemical structure, C20H24N4O3, CAS 433329-16-9
1-[4-[3-(Benzylamino)-4-nitrophenyl]piperazin-1-yl]propan-1-one
CAS 433329-16-9C20H24N4O3
1-[4-[4-Nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]propan-1-one chemical structure, C21H26N4O3, CAS 433702-89-7
1-[4-[4-Nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]propan-1-one
CAS 433702-89-7C21H26N4O3
N,N-Dimethyl-4-[4-nitro-3-(1-phenylethylamino)phenyl]piperazine-1-sulfonamide chemical structure, C20H27N5O4S, CAS 434295-08-6
N,N-Dimethyl-4-[4-nitro-3-(1-phenylethylamino)phenyl]piperazine-1-sulfonamide
CAS 434295-08-6C20H27N5O4S
1-[4-[4-Nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]butan-1-one chemical structure, C22H28N4O3, CAS 509113-54-6
1-[4-[4-Nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]butan-1-one
CAS 509113-54-6C22H28N4O3
4-[3-(Benzylamino)-4-nitrophenyl]-N,N-dimethylpiperazine-1-sulfonamide chemical structure, C19H25N5O4S, CAS 524033-65-6
4-[3-(Benzylamino)-4-nitrophenyl]-N,N-dimethylpiperazine-1-sulfonamide
CAS 524033-65-6C19H25N5O4S
2,2-Dimethyl-1-[4-[4-nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]propan-1-one chemical structure, C23H30N4O3, CAS 524033-60-1
2,2-Dimethyl-1-[4-[4-nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]propan-1-one
CAS 524033-60-1C23H30N4O3
3-Methyl-1-[4-[4-nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]butan-1-one chemical structure, C23H30N4O3, CAS 591736-21-9
3-Methyl-1-[4-[4-nitro-3-(1-phenylethylamino)phenyl]piperazin-1-yl]butan-1-one
CAS 591736-21-9C23H30N4O3