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Murcko scaffold

Ring system with 3 rings and 20 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
8
With full pages
5
Scaffold SMILES

c1ccc(CSc2nccc(N3CCOCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSc2nccc(N3CCOCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

4-{2-[(4-Methoxybenzyl)sulfanyl]-6-[(methylsulfanyl)methyl]-4-pyrimidinyl}morpholine chemical structure, C18H23N3O2S2, CAS 303985-02-6
4-{2-[(4-Methoxybenzyl)sulfanyl]-6-[(methylsulfanyl)methyl]-4-pyrimidinyl}morpholine
CAS 303985-02-6C18H23N3O2S2
4-[2-[(3,4-Dichlorophenyl)methylthio]-6-[(methylthio)methyl]-4-pyrimidinyl]morpholine chemical structure, C17H19Cl2N3OS2, CAS 341965-63-7
4-[2-[(3,4-Dichlorophenyl)methylthio]-6-[(methylthio)methyl]-4-pyrimidinyl]morpholine
CAS 341965-63-7C17H19Cl2N3OS2
4-{2-[(2,4-Dichlorobenzyl)sulfanyl]-6-[(methylsulfanyl)methyl]-4-pyrimidinyl}morpholine chemical structure, C17H19Cl2N3OS2, CAS 341965-72-8
4-{2-[(2,4-Dichlorobenzyl)sulfanyl]-6-[(methylsulfanyl)methyl]-4-pyrimidinyl}morpholine
CAS 341965-72-8C17H19Cl2N3OS2
4-[2-[(2,4-Dichlorophenyl)methylthio]-6-methyl-4-pyrimidinyl]morpholine chemical structure, C16H17Cl2N3OS, CAS 339017-82-2
4-[2-[(2,4-Dichlorophenyl)methylthio]-6-methyl-4-pyrimidinyl]morpholine
CAS 339017-82-2C16H17Cl2N3OS
Benzeneacetic acid, alpha-((4-methyl-6-(4-morpholinyl)-2-pyrimidinyl)thio)- chemical structure, C17H19N3O3S, CAS 87125-97-1
Benzeneacetic acid, alpha-((4-methyl-6-(4-morpholinyl)-2-pyrimidinyl)thio)-
CAS 87125-97-1C17H19N3O3S
4-[2-[(4-Chlorobenzyl)sulfanyl]-6-(methoxymethyl)-4-pyrimidinyl]morpholine chemical structure, C17H20ClN3O2S, CAS 478041-43-9
4-[2-[(4-Chlorobenzyl)sulfanyl]-6-(methoxymethyl)-4-pyrimidinyl]morpholine
CAS 478041-43-9C17H20ClN3O2S
Methyl 4-(((4-methyl-6-morpholinopyrimidin-2-yl)thio)methyl)benzoate chemical structure, C18H21N3O3S, CAS 946358-56-1
Methyl 4-(((4-methyl-6-morpholinopyrimidin-2-yl)thio)methyl)benzoate
CAS 946358-56-1C18H21N3O3S
4-(2-{[(4-Methoxyphenyl)methyl]sulfanyl}-6-methylpyrimidin-4-yl)morpholine chemical structure, C17H21N3O2S, CAS 1110968-57-4
4-(2-{[(4-Methoxyphenyl)methyl]sulfanyl}-6-methylpyrimidin-4-yl)morpholine
CAS 1110968-57-4C17H21N3O2S