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Murcko scaffold

Ring system with 3 rings and 19 atoms

82 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
82
With full pages
3
Scaffold SMILES

O=c1cc(NCc2ccccc2)c2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(NCc2ccccc2)c2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 82 chemicals

4-(Benzylamino)-1-methyl-3-nitro-2(1H)-quinolinone chemical structure, C17H15N3O3, CAS 141945-52-0
4-(Benzylamino)-1-methyl-3-nitro-2(1H)-quinolinone
CAS 141945-52-0C17H15N3O3
4-[Benzyl(methyl)amino]-1-methyl-3-nitroquinolin-2-one chemical structure, C18H17N3O3, CAS 850803-28-0
4-[Benzyl(methyl)amino]-1-methyl-3-nitroquinolin-2-one
CAS 850803-28-0C18H17N3O3
4-((4-Methoxybenzyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one chemical structure, C18H17N3O4, CAS 849924-11-4
4-((4-Methoxybenzyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one
CAS 849924-11-4C18H17N3O4
4-((2-Chlorobenzyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one chemical structure, C17H14ClN3O3, CAS 850189-09-2
4-((2-Chlorobenzyl)amino)-1-methyl-3-nitroquinolin-2(1H)-one
CAS 850189-09-2C17H14ClN3O3
1-Methyl-3-nitro-4-((1-phenylethyl)amino)quinolin-2(1H)-one chemical structure, C18H17N3O3, CAS 850719-57-2
1-Methyl-3-nitro-4-((1-phenylethyl)amino)quinolin-2(1H)-one
CAS 850719-57-2C18H17N3O3
4-(Benzyl(2-hydroxyethyl)amino)-1-ethyl-3-nitroquinolin-2(1H)-one chemical structure, C20H21N3O4, CAS 886160-88-9
4-(Benzyl(2-hydroxyethyl)amino)-1-ethyl-3-nitroquinolin-2(1H)-one
CAS 886160-88-9C20H21N3O4
Ethyl 4-((2-methoxybenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C20H20N2O4, CAS 1251625-12-3
Ethyl 4-((2-methoxybenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251625-12-3C20H20N2O4
Ethyl 4-((3-chlorobenzyl)amino)-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C19H16ClFN2O3, CAS 1251686-94-8
Ethyl 4-((3-chlorobenzyl)amino)-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251686-94-8C19H16ClFN2O3
Ethyl 4-(benzylamino)-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C19H17FN2O3, CAS 1251595-92-2
Ethyl 4-(benzylamino)-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251595-92-2C19H17FN2O3
Ethyl 6-fluoro-4-((2-methoxybenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C20H19FN2O4, CAS 1251616-90-6
Ethyl 6-fluoro-4-((2-methoxybenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251616-90-6C20H19FN2O4
Ethyl 4-((4-chlorobenzyl)amino)-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C19H16ClFN2O3, CAS 1251562-07-8
Ethyl 4-((4-chlorobenzyl)amino)-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251562-07-8C19H16ClFN2O3
Ethyl 6-fluoro-4-((4-methoxybenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C20H19FN2O4, CAS 1251602-01-3
Ethyl 6-fluoro-4-((4-methoxybenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251602-01-3C20H19FN2O4
Ethyl 6-fluoro-4-((4-methylbenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C20H19FN2O3, CAS 1251595-97-7
Ethyl 6-fluoro-4-((4-methylbenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251595-97-7C20H19FN2O3
Ethyl 6-fluoro-4-((2-fluorobenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C19H16F2N2O3, CAS 1251675-96-3
Ethyl 6-fluoro-4-((2-fluorobenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251675-96-3C19H16F2N2O3
Ethyl 6-fluoro-4-((3-methoxybenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C20H19FN2O4, CAS 1251609-80-9
Ethyl 6-fluoro-4-((3-methoxybenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251609-80-9C20H19FN2O4
Ethyl 6-fluoro-4-((4-(methylthio)benzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C20H19FN2O3S, CAS 1251543-44-8
Ethyl 6-fluoro-4-((4-(methylthio)benzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251543-44-8C20H19FN2O3S
Ethyl 4-((2,4-difluorobenzyl)amino)-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C19H15F3N2O3, CAS 1251625-17-8
Ethyl 4-((2,4-difluorobenzyl)amino)-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251625-17-8C19H15F3N2O3
Ethyl 6-fluoro-4-((2-methylbenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C20H19FN2O3, CAS 1251670-71-9
Ethyl 6-fluoro-4-((2-methylbenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251670-71-9C20H19FN2O3
Ethyl 4-{[(4-ethylphenyl)methyl]amino}-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C21H21FN2O3, CAS 1243044-24-7
Ethyl 4-{[(4-ethylphenyl)methyl]amino}-6-fluoro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1243044-24-7C21H21FN2O3
Ethyl 4-((2-methoxybenzyl)amino)-8-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C21H22N2O4, CAS 1251596-07-2
Ethyl 4-((2-methoxybenzyl)amino)-8-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251596-07-2C21H22N2O4
Ethyl 4-((4-chlorobenzyl)amino)-8-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C20H19ClN2O3, CAS 1243005-35-7
Ethyl 4-((4-chlorobenzyl)amino)-8-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1243005-35-7C20H19ClN2O3
Ethyl 4-((4-methoxybenzyl)amino)-8-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C21H22N2O4, CAS 1251596-09-4
Ethyl 4-((4-methoxybenzyl)amino)-8-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251596-09-4C21H22N2O4
Ethyl 8-methyl-4-((4-methylbenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C21H22N2O3, CAS 1242866-44-9
Ethyl 8-methyl-4-((4-methylbenzyl)amino)-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1242866-44-9C21H22N2O3
Ethyl 4-((2-fluorobenzyl)amino)-8-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate chemical structure, C20H19FN2O3, CAS 1251670-89-9
Ethyl 4-((2-fluorobenzyl)amino)-8-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS 1251670-89-9C20H19FN2O3